Vastus medialis motor unit properties in knee osteoarthritis.

BACKGROUND: Maximal isometric quadriceps strength deficits have been widely reported in studies of knee osteoarthritis (OA), however little is known about the effect of osteoarthritis knee pain on submaximal quadriceps neuromuscular function. The purpose of this study was to measure vastus medialis motor unit (MU) properties in participants with knee OA, during submaximal isometric contractions. METHODS: Vastus medialis motor unit potential (MUP) parameters were assessed in 8 patients with knee OA and 8 healthy, sex and age-matched controls during submaximal isometric contractions (20% of maximum isometric torque). Unpaired t-tests were used to compare groups for demographic and muscle parameters. RESULTS: Maximum knee extension torque was ~22% lower in the OA group, a difference that was not statistically significantly (p = 0.11). During submaximal contractions, size related parameters of the needle MUPs (e.g. negative peak duration and amplitude-to-area ratio) were greater in the OA group (p < 0.05), with a rightward shift in the frequency distribution of surface MUP negative peak amplitude. MUP firing rates were significantly lower in the OA group (p < 0.05). CONCLUSIONS: Changes in MU recruitment and rate coding strategies in OA may reflect a chronic reinnervation process or a compensatory strategy in the presence of chronic knee pain associated with OA.

Glenoid vault endosteal dimensions: an anthropometric study with special interest in implant design.

An understanding of the morphology of the glenoid is important from the viewpoint of implant design and selection. This study describes the endosteal dimensions and shape of the glenoid and correlates these results with age, gender, and the presence of osteoarthritis. This study used 72 scapulae. Data were obtained from computed tomography scans of both cadaveric and in vivo glenoids. The glenoid is relatively straight-sided in the coronal plane and more highly fluted in the transverse plane. The endosteal dimensions were larger for male specimens, but there was no difference in endosteal shape with respect to gender. These findings were not influenced by age or the presence of osteoarthritis. This study suggests that traditional glenoid component designs may not be optimal. To maximize fixation, a rectangular keel may be most effective in the coronal plane and a triangular keel may be most effective in the transverse plane.

The influence of implant articular thickness and glenohumeral conformity on stability of an all-metal glenoid component.

The objective of this study was to determine the effect of implant thickness and glenohumeral conformity on fixation of an all-metal glenoid component. A stainless steel glenoid component was designed and implanted in 10 cadaveric scapulae. A testing apparatus capable of producing a loading vector at various angles, magnitudes, and directions was used. The independent variables included 6 directions and 3 angles of joint load, 3 implant thicknesses, and 4 glenohumeral conformities. Implant micromotion relative to bone was measured by use of 4 displacement transducers at the superior, inferior, anterior, and posterior sites. The components displayed a consistent response to loading of ipsilateral compression and contralateral distraction. Stability decreased as the load application angle increased (P < .05). A decrease in the implant thickness and glenohumeral conformity resulted in increased implant stability (P < .05). Decreasing implant thickness and glenohumeral conformity reduce the eccentric component of loading and may improve the durability of glenoid implants.

Effect of polyethylene component thickness on range of motion and stability in primary total knee arthroplasty.

Total knee arthroplasty (TKA) is a common procedure with good survivorship and functional results. Optimal results are dependent on proper osseous cuts and soft tissue balancing. Soft tissue tensioning via the polyethylene spacer thickness is an important component of soft tissue balancing. Increased thickness increases soft tissue tension and, therefore, has the potential to increase stability but decrease range of motion (ROM). Decreased polyethylene thickness may decrease soft tissue tension and has the potential to increase ROM but decrease stability. Using computer-based navigation, the intraoperative effect of increasing and decreasing polyethylene thickness in 1-mm increments on ROM and coronal stability throughout the ROM of 35 patients was examined. It was found that increasing the polyethylene thickness by 1-mm increments had a statistically significant impact on the ability to achieve full extension but had no impact on flexion. Increased polyethylene thickness decreased coronal plane motion. Coronal plane laxity increased with increased flexion irrespective of polyethylene thickness. In this patient cohort, lateral laxity became >1° when the knee was flexed. However, medial structures prevented valgus angulation of >1° in all scenarios except when the polyethylene was diminished by 2 mm. Changes in polyethylene thickness had an impact on the ability to gain full extension and coronal plane motion.

Wear rate of highly cross-linked polyethylene in total hip arthroplasty. A randomized controlled trial.

BACKGROUND: Highly cross-linked polyethylene was introduced for clinical use in total hip arthroplasty with the expectation that it would exhibit less wear when compared with conventional polyethylene. The purpose of this study was to report the clinical and radiographic results, after a minimum of five years of follow-up, of a randomized, blinded, controlled trial comparing a conventional polyethylene with a first-generation highly cross-linked polyethylene. METHODS: One hundred patients were enrolled in a prospective, randomized controlled study comparing highly cross-linked and conventional polyethylene acetabular liners in total hip arthroplasty. Fifty patients were in each group. At the time of follow-up, clinical outcomes were assessed and steady-state femoral head penetration rates (after bedding-in) for each patient were calculated with use of a validated radiographic technique. In addition, a statistical comparison of polyethylene wear between groups was performed with use of generalized estimating equations. RESULTS: At a mean of 6.8 years postoperatively, there were no differences between the two polyethylene groups with regard to the Harris hip score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), or Short Form-12 (SF-12) score. The mean femoral head penetration rate in the first through fifth years was found to be significantly lower in the group treated with the highly cross-linked polyethylene (0.003 mm/yr [95% confidence interval, +/-0.027]) than it was in the group treated with conventional polyethylene (0.051 mm/yr [95% confidence interval, +/-0.022]) (p=0.006). Men treated with a conventional polyethylene liner had a significantly higher (p

Computer-assisted gap equalization in total knee arthroplasty.

This in vitro biomechanical study compared a conventional balancing technique in knee arthroplasty to a technique using computer assistance. The experimental technique used a soft tissue tensioner instrumented with computer-monitored load cells to quantify soft tissue tension. To assess outcome, a tibial load transducer measured medial and lateral compartment forces and tibial rotation. An electromagnetic tracking system quantified knee position under simulated muscle loading. The computer-assisted technique improved knee balance before insertion of components. However, once components were implanted, there was no difference in knee load balance between the 2 techniques. No correlation was shown between compartmental load balance and tibial rotation or mechanical axis misalignment. Although computer-assisted surgery may improve technical accuracy, further work is necessary to achieve an optimal final knee load balance.

Load balance in total knee arthroplasty: an in vitro analysis.

BACKGROUND: One of the goals of total knee arthroplasty (TKA) is to balance the loads between the compartments of the knee. An instrumented load cell that measures compartment loads in real time is utilized to evaluate conventional, qualitative methods of achieving this balance. METHODS: TKA was performed on 10 cadaveric knees. Prior to and after load balancing, compartment forces were measured at flexion angles of 0-90 degrees. Knees were randomly assigned into one of two groups, based upon whether or not the surgeons could visualize the load cell's output during balancing. RESULTS: Prior to attempting load balance, there were significant differences between the medial and lateral compartment loads for all knees (p < 0.05). After attempting balance with the aid of the load cell, there was equal load balance at all angles studied. Without the aid of the load cell, balance was not consistently achieved at every angle. CONCLUSIONS: Conventional load balancing techniques in TKA are not perfect.

Does keel size, the use of screws, and the use of bone cement affect fixation of a metal glenoid implant?

The objective of this study was to determine the effect of screws and keel size on the fixation of an all-metal glenoid component. A prototype stainless-steel glenoid component was designed and implanted in 10 cadaveric scapulae. A testing apparatus capable of producing a loading vector at various angles, magnitudes, and directions was used. The independent variables included six directions and three angles of joint load, and five fixation modalities-three different-sized cross-keels (small, medium, and large), screws, and bone cement. Implant micromotion relative to bone was measured by four displacement transducers at the superior, inferior, anterior, and posterior sites. The components displayed a consistent response to loading of ipsilateral compression and contralateral distraction. Use of progressively larger keels did not significantly improve implant stability. Stability decreased as the angle of load application increased (P <.05). Screw and cement fixation resulted in the most stable fixation (P <.05).

Patellar position after total knee arthroplasty: influence of femoral component malposition.

Patellar shift, tilt, and rotation were analyzed in 7 cadaveric knee specimens during simulated quadriceps loading, in the intact knee, and after implant reconstruction. Femoral component medialization, lateralization, and external rotation were also investigated. Relative motion of the patella with respect to the femur was measured using an electromagnetic tracking system. The spatial position of the patella did not change with standardized total knee arthroplasty (P <.05). After malpositioning of the femoral component, patellar rotation also did not change (P >.05); however, patellar tilt was altered by femoral component external rotation malposition (P <.05), and patellar shift was affected by all femoral component malpositions (P <.05). The spatial position of the patella relative to the femoral shaft was changed with any femoral component malposition, suggesting that the soft tissues were abnormally tensioned. This could result in subsequent wear on the patellar component and, therefore, early failure.