Pesquisa | BVS Violência e Saúde

1.

Principles and therapeutic applications of adaptive immunity.

Chi, Hongbo; Pepper, Marion; Thomas, Paul G.

Cell ; 187(9): 2052-2078, 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38670065

2.

Polyamine: A metabolic compass for T helper cell fate direction.

Shi, Hao; Chi, Hongbo.

Cell ; 184(16): 4109-4112, 2021 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-34358466

3.

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8⁺ T cell fate decisions.

Huang, Hongling; Zhou, Peipei; Wei, Jun; Long, Lingyun; Shi, Hao; Dhungana, Yogesh; Chapman, Nicole M; Fu, Guotong; Saravia, Jordy; Raynor, Jana L; Liu, Shaofeng; Palacios, Gustavo; Wang, Yong-Dong; Qian, Chenxi; Yu, Jiyang; Chi, Hongbo.

Cell ; 184(5): 1245-1261.e21, 2021 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-33636132

4.

CXCR6 orchestrates brain CD8⁺ T cell residency and limits mouse Alzheimer's disease pathology.

Su, Wei; Saravia, Jordy; Risch, Isabel; Rankin, Sherri; Guy, Cliff; Chapman, Nicole M; Shi, Hao; Sun, Yu; Kc, Anil; Li, Wei; Huang, Hongling; Lim, Seon Ah; Hu, Haoran; Wang, Yan; Liu, Danting; Jiao, Yun; Chen, Ping-Chung; Soliman, Hadeer; Yan, Koon-Kiu; Zhang, Jonathan; Vogel, Peter; Liu, Xueyan; Serrano, Geidy E; Beach, Thomas G; Yu, Jiyang; Peng, Junmin; Chi, Hongbo.

Nat Immunol ; 24(10): 1735-1747, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37679549

5.

Universal Principled Review: A Community-Driven Method to Improve Peer Review.

Krummel, Matthew; Blish, Catherine; Kuhns, Michael; Cadwell, Ken; Oberst, Andrew; Goldrath, Ananda; Ansel, K Mark; Chi, Hongbo; O'Connell, Ryan; Wherry, E John; Pepper, Marion.

Cell ; 179(7): 1441-1445, 2019 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-31835023

6.

Novel specialized cell state and spatial compartments within the germinal center.

Kennedy, Domenick E; Okoreeh, Michael K; Maienschein-Cline, Mark; Ai, Junting; Veselits, Margaret; McLean, Kaitlin C; Dhungana, Yogesh; Wang, Hong; Peng, Junmin; Chi, Hongbo; Mandal, Malay; Clark, Marcus R.

Nat Immunol ; 21(6): 660-670, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32341509

7.

Metabolic adaptation of lymphocytes in immunity and disease.

Chapman, Nicole M; Chi, Hongbo.

Immunity ; 55(1): 14-30, 2022 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-35021054

8.

Maintenance of CD4 T cell fitness through regulation of Foxo1.

Newton, Ryan H; Shrestha, Sharad; Sullivan, Jenna M; Yates, Kathleen B; Compeer, Ewoud B; Ron-Harel, Noga; Blazar, Bruce R; Bensinger, Steven J; Haining, W Nicholas; Dustin, Michael L; Campbell, Daniel J; Chi, Hongbo; Turka, Laurence A.

Nat Immunol ; 19(8): 838-848, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29988091

9.

mTORC2 forms iron-clad defense to guard memory.

Saravia, Jordy; Chi, Hongbo.

Nat Immunol ; 23(2): 155-156, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35058617

10.

Preventing Ubiquitination Improves CAR T Cell Therapy via 'CAR Merry-Go-Around'.

Chapman, Nicole M; Gottschalk, Stephen; Chi, Hongbo.

Immunity ; 53(2): 243-245, 2020 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-32814023

11.

Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer.

Zhou, Peipei; Shi, Hao; Huang, Hongling; Sun, Xiang; Yuan, Sujing; Chapman, Nicole M; Connelly, Jon P; Lim, Seon Ah; Saravia, Jordy; Kc, Anil; Pruett-Miller, Shondra M; Chi, Hongbo.

Nature ; 624(7990): 154-163, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37968405

12.

SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.

Guo, Chuansheng; You, Zhiyuan; Shi, Hao; Sun, Yu; Du, Xingrong; Palacios, Gustavo; Guy, Cliff; Yuan, Sujing; Chapman, Nicole M; Lim, Seon Ah; Sun, Xiang; Saravia, Jordy; Rankin, Sherri; Dhungana, Yogesh; Chi, Hongbo.

Nature ; 620(7972): 200-208, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37407815

13.

Metabolic programs of T cell tissue residency empower tumour immunity.

Reina-Campos, Miguel; Heeg, Maximilian; Kennewick, Kelly; Mathews, Ian T; Galletti, Giovanni; Luna, Vida; Nguyen, Quynhanh; Huang, Hongling; Milner, J Justin; Hu, Kenneth H; Vichaidit, Amy; Santillano, Natalie; Boland, Brigid S; Chang, John T; Jain, Mohit; Sharma, Sonia; Krummel, Matthew F; Chi, Hongbo; Bensinger, Steven J; Goldrath, Ananda W.

Nature ; 621(7977): 179-187, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37648857

14.

Trans-vaccenic acid reprograms CD8⁺ T cells and anti-tumour immunity.

Fan, Hao; Xia, Siyuan; Xiang, Junhong; Li, Yuancheng; Ross, Matthew O; Lim, Seon Ah; Yang, Fan; Tu, Jiayi; Xie, Lishi; Dougherty, Urszula; Zhang, Freya Q; Zheng, Zhong; Zhang, Rukang; Wu, Rong; Dong, Lei; Su, Rui; Chen, Xiufen; Althaus, Thomas; Riedell, Peter A; Jonker, Patrick B; Muir, Alexander; Lesinski, Gregory B; Rafiq, Sarwish; Dhodapkar, Madhav V; Stock, Wendy; Odenike, Olatoyosi; Patel, Anand A; Opferman, Joseph; Tsuji, Takemasa; Matsuzaki, Junko; Shah, Hardik; Faubert, Brandon; Elf, Shannon E; Layden, Brian; Bissonnette, B Marc; He, Yu-Ying; Kline, Justin; Mao, Hui; Odunsi, Kunle; Gao, Xue; Chi, Hongbo; He, Chuan; Chen, Jing.

Nature ; 623(7989): 1034-1043, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37993715

15.

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis.

Wei, Jun; Long, Lingyun; Yang, Kai; Guy, Cliff; Shrestha, Sharad; Chen, Zuojia; Wu, Chuan; Vogel, Peter; Neale, Geoffrey; Green, Douglas R; Chi, Hongbo.

Nat Immunol ; 17(3): 277-85, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26808230

16.

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.

Shi, Hao; Chapman, Nicole M; Wen, Jing; Guy, Cliff; Long, Lingyun; Dhungana, Yogesh; Rankin, Sherri; Pelletier, Stephane; Vogel, Peter; Wang, Hong; Peng, Junmin; Guan, Kun-Liang; Chi, Hongbo.

Immunity ; 51(6): 1012-1027.e7, 2019 12 17.

Artigo em Inglês | MEDLINE | ID: mdl-31668641

17.

cBAF complex components and MYC cooperate early in CD8⁺ T cell fate.

Guo, Ao; Huang, Hongling; Zhu, Zhexin; Chen, Mark J; Shi, Hao; Yuan, Sujing; Sharma, Piyush; Connelly, Jon P; Liedmann, Swantje; Dhungana, Yogesh; Li, Zhenrui; Haydar, Dalia; Yang, Mao; Beere, Helen; Yustein, Jason T; DeRenzo, Christopher; Pruett-Miller, Shondra M; Crawford, Jeremy Chase; Krenciute, Giedre; Roberts, Charles W M; Chi, Hongbo; Green, Douglas R.

Nature ; 607(7917): 135-141, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35732731

18.

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

Shrestha, Sharad; Yang, Kai; Guy, Cliff; Vogel, Peter; Neale, Geoffrey; Chi, Hongbo.

Nat Immunol ; 16(2): 178-87, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25559258

19.

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Shi, Hao; Liu, Chaohong; Tan, Haiyan; Li, Yuxin; Nguyen, Thanh-Long M; Dhungana, Yogesh; Guy, Cliff; Vogel, Peter; Neale, Geoffrey; Rankin, Sherri; Feng, Yongqiang; Peng, Junmin; Tao, Wufan; Chi, Hongbo.

Immunity ; 49(5): 899-914.e6, 2018 11 20.

Artigo em Inglês | MEDLINE | ID: mdl-30413360

20.

Lipid signalling enforces functional specialization of T_reg cells in tumours.

Lim, Seon Ah; Wei, Jun; Nguyen, Thanh-Long M; Shi, Hao; Su, Wei; Palacios, Gustavo; Dhungana, Yogesh; Chapman, Nicole M; Long, Lingyun; Saravia, Jordy; Vogel, Peter; Chi, Hongbo.

Nature ; 591(7849): 306-311, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33627871

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