Detalhe da pesquisa
1.
Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management.
Neurosignals
; 22(1): 52-63, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25095809
2.
Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types.
Planta Med
; 78(2): 115-21, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22083896
3.
Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.
J Immunol
; 181(10): 7400-6, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18981163
4.
Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.
Oncogene
; 24(33): 5262-8, 2005 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15940257
5.
A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
Cancer Res
; 63(14): 3931-9, 2003 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12873987
6.
In vitro intestinal absorption and first-pass intestinal and hepatic metabolism of cycloastragenol, a potent small molecule telomerase activator.
Drug Metab Pharmacokinet
; 25(5): 477-86, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20877137
7.
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
Hepatology
; 42(5): 1127-36, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16114043
8.
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Blood
; 103(1): 258-66, 2004 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12969977