Detalhe da pesquisa
1.
Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes.
Pharm Res
; 30(2): 342-51, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22983644
2.
Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs.
Chem Phys Lipids
; 243: 105178, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122738
3.
Development of an mRNA replacement therapy for phenylketonuria.
Mol Ther Nucleic Acids
; 28: 87-98, 2022 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35356682
4.
Lipid nanoparticle delivers phenylalanine ammonia lyase mRNA to the liver leading to catabolism and clearance of phenylalanine in a phenylketonuria mouse model.
Mol Genet Metab Rep
; 32: 100882, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35600090
5.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Mol Metab
; 60: 101487, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378329
6.
Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS.
Mol Ther Nucleic Acids
; 24: 1-10, 2021 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33738134
7.
Property-Driven Design and Development of Lipids for Efficient Delivery of siRNA.
J Med Chem
; 63(21): 12992-13012, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33119286
8.
Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models.
Front Microbiol
; 11: 832, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32508764
9.
CD8+ T cells mediate protection against Zika virus induced by an NS3-based vaccine.
Sci Adv
; 6(45)2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148638
10.
Immune modulatory nanoparticle therapeutics for intracerebral glioma.
Neuro Oncol
; 19(3): 372-382, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27765835
11.
Synthesis and characterization of novel aromatic azo bond-containing pH-sensitive and hydrolytically cleavable IPN hydrogels.
Biomaterials
; 27(7): 1140-51, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098577
12.
Effect of molecular weight of PGG-paclitaxel conjugates on in vitro and in vivo efficacy.
J Control Release
; 161(1): 124-31, 2012 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22521595
13.
Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel.
J Control Release
; 140(3): 277-83, 2009 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19699770