Detalhe da pesquisa
1.
Drug transporters in drug disposition - the year 2022 in review.
Drug Metab Rev
; 55(4): 343-370, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644867
2.
Innovations, Opportunities, and Challenges for Predicting Alteration in Drug-Metabolizing Enzyme and Transporter Activity in Specific Populations.
Drug Metab Dispos
; 51(12): 1547-1550, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775331
3.
Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.
Drug Metab Dispos
; 51(10): 1391-1402, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524541
4.
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome.
Mol Pharm
; 20(7): 3505-3518, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37283406
5.
Novel insights in drug transporter sciences: the year 2021 in review.
Drug Metab Rev
; 54(3): 299-317, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35762758
6.
Sinusoidal Uptake Determines the Hepatic Clearance of Pevonedistat (TAK-924) as Explained by Extended Clearance Model.
Drug Metab Dispos
; 50(7): 980-988, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545257
7.
Recent advances in drug transporter sciences: highlights from the year 2020.
Drug Metab Rev
; 53(3): 321-349, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34346798
8.
Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes.
Drug Metab Dispos
; 49(4): 314-321, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472814
9.
Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2).
Mol Pharm
; 16(8): 3569-3576, 2019 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31194565
10.
Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers.
Biochim Biophys Acta Biomembr
; 1860(3): 645-653, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29198943
11.
Assessment of Transporter-Mediated and Passive Hepatic Uptake Clearance Using Rifamycin-SV as a Pan-Inhibitor of Active Uptake.
Mol Pharm
; 15(10): 4677-4688, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29996058
12.
Quantitative Prediction of CYP3A4 Induction: Impact of Measured, Free, and Intracellular Perpetrator Concentrations from Human Hepatocyte Induction Studies on Drug-Drug Interaction Predictions.
Drug Metab Dispos
; 45(6): 692-705, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28336578
13.
Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes.
Drug Metab Dispos
; 44(12): 1910-1919, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27655038
14.
Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).
Biochem J
; 459(2): 301-12, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24498857
15.
Toward improved predictions of pharmacokinetics of transported drugs in hepatic impairment: Insights from the extended clearance model.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 118-131, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833845
16.
Identification of novel breast cancer resistance protein (BCRP) inhibitors by virtual screening.
Mol Pharm
; 10(4): 1236-48, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418667
17.
Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes.
CPT Pharmacometrics Syst Pharmacol
; 12(2): 261-273, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36540952
18.
Utilization of OATP1B Biomarker Coproporphyrin-I to Guide Drug-Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry.
Clin Pharmacol Ther
; 114(6): 1170-1183, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37750401
19.
Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate.
Glia
; 60(3): 333-42, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072423
20.
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans.
Pharmacol Ther
; 238: 108271, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002079