Detalhe da pesquisa
1.
Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis.
EMBO J
; 38(13): e100926, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31268602
2.
HRMAn 2.0: Next-generation artificial intelligence-driven analysis for broad host-pathogen interactions.
Cell Microbiol
; 23(7): e13349, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33930228
3.
K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells.
PLoS Pathog
; 12(11): e1006027, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875583
4.
Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii.
Cell Microbiol
; 18(8): 1056-64, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26874079
5.
Human immunity to Toxoplasma gondii.
PLoS Pathog
; 15(12): e1008097, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31830133
6.
Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.
Antimicrob Agents Chemother
; 58(10): 6032-43, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070106
7.
Differential development of antibiotic resistance and virulence between Acinetobacter species.
mSphere
; 9(5): e0010924, 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38578105
8.
Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication.
Infect Immun
; 81(12): 4341-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24042117
9.
Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).
Bioorg Med Chem Lett
; 23(10): 3064-9, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23570789
10.
Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues.
Bioorg Med Chem Lett
; 23(21): 6019-24, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035097
11.
Human guanylate-binding proteins in intracellular pathogen detection, destruction, and host cell death induction.
Curr Opin Immunol
; 84: 102373, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37536111
12.
p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells.
mSphere
; 8(6): e0051123, 2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975677
13.
PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Science
; 382(6666): eadg2253, 2023 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797010
14.
Toxoplasma-proximal and distal control by GBPs in human macrophages.
Pathog Dis
; 79(9)2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931666
15.
Image-Based Quantitation of Host Cell-Toxoplasma gondii Interplay Using HRMAn: A Host Response to Microbe Analysis Pipeline.
Methods Mol Biol
; 2071: 411-433, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31758464
16.
Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection.
mSphere
; 5(5)2020 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907956
17.
Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death.
Cell Rep
; 32(6): 108008, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32783936
18.
C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo.
Wellcome Open Res
; 4: 124, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544161
19.
Defining host-pathogen interactions employing an artificial intelligence workflow.
Elife
; 82019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744806
20.
The Toxoplasma Parasitophorous Vacuole: An Evolving Host-Parasite Frontier.
Trends Parasitol
; 33(6): 473-488, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28330745