Detalhe da pesquisa
1.
Accelerating therapeutics development during a pandemic: population pharmacokinetics of the long-acting antibody combination AZD7442 (tixagevimab/cilgavimab) in the prophylaxis and treatment of COVID-19.
Antimicrob Agents Chemother
; 68(5): e0158723, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38534112
2.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152087
3.
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
; 506(7489): 503-6, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463523
4.
Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets.
Proc Natl Acad Sci U S A
; 114(26): E5094-E5102, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607050
5.
Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138566
6.
Use of precision cut lung slices as a translational model for the study of lung biology.
Respir Res
; 20(1): 162, 2019 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31324219
7.
The Neutrophilic Response to Pseudomonas Damages the Airway Barrier, Promoting Infection by Klebsiella pneumoniae.
Am J Respir Cell Mol Biol
; 59(6): 745-756, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109945
8.
Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice.
Antimicrob Agents Chemother
; 62(3)2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311091
9.
Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage.
PLoS Pathog
; 11(4): e1004820, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25880560
10.
Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4.
PLoS Pathog
; 9(10): e1003682, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24098127
11.
Serum AZD7442 (tixagevimab-cilgavimab) concentrations and in vitroIC50 values predict SARS-CoV-2 neutralising antibody titres.
Clin Transl Immunology
; 13(6): e1517, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38873124
12.
Safety, Efficacy and Pharmacokinetics of AZD7442 (Tixagevimab/Cilgavimab) for Treatment of Mild-to-Moderate COVID-19: 15-Month Final Analysis of the TACKLE Trial.
Infect Dis Ther
; 13(3): 521-533, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38403865
13.
Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH.
Biochim Biophys Acta Mol Basis Dis
; 1869(6): 166697, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37054999
14.
Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells.
Am J Respir Cell Mol Biol
; 46(1): 6-13, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21778412
15.
Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity.
J Biol Chem
; 286(41): 35891-35898, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21878647
16.
Resident macrophages of the lung and liver: The guardians of our tissues.
Front Immunol
; 13: 1029085, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36532044
17.
Serum levels of anti-PF4 IgG after AZD1222 (ChAdOx1 nCoV-19) vaccination.
Sci Rep
; 12(1): 7961, 2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35562373
18.
SARS-CoV-2 Spike Protein Expression In Vitro and Hematologic Effects in Mice Vaccinated With AZD1222 (ChAdOx1 nCoV-19).
Front Immunol
; 13: 836492, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35493482
19.
Therapeutic potential of plasma gelsolin administration in a rat model of sepsis.
Cytokine
; 54(3): 235-8, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21420877
20.
Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen.
Microorganisms
; 9(7)2021 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209573