Detalhe da pesquisa
1.
Christian Personalism versus Utilitarianism: An Analysis of Their Approaches to Love and Suffering.
Linacre Q
; 87(4): 425-437, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-33100390
2.
Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.
Mol Ther
; 26(9): 2282-2294, 2018 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30196853
3.
Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice.
Mol Ther
; 26(2): 496-509, 2018 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29292164
4.
Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity.
Stroke
; 48(5): 1420-1423, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325846
5.
Long-term rescue of cone photoreceptor degeneration in retinitis pigmentosa 2 (RP2)-knockout mice by gene replacement therapy.
Hum Mol Genet
; 24(22): 6446-58, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26358772
6.
A long-term efficacy study of gene replacement therapy for RPGR-associated retinal degeneration.
Hum Mol Genet
; 24(14): 3956-70, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25877300
7.
Diabetes enhances the efficacy of AAV2 vectors in the retina: therapeutic effect of AAV2 encoding vasoinhibin and soluble VEGF receptor 1.
Lab Invest
; 96(3): 283-95, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26568297
8.
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Proc Natl Acad Sci U S A
; 107(27): 12216-21, 2010 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566880
9.
Application of in-vitro-cultured primary hepatocytes to evaluate species translatability and AAV transduction mechanisms of action.
Mol Ther Methods Clin Dev
; 26: 61-71, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35782594
10.
Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.
J Biol Chem
; 285(20): 15500-15510, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231273
11.
Effect of genome size on AAV vector packaging.
Mol Ther
; 18(1): 80-6, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19904234
12.
Bill of rights for children.
Linacre Q
; 81(4): 298-301, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25473129
13.
A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration.
Cell Rep
; 25(3): 611-623.e6, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332642
14.
Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography.
J Virol Methods
; 140(1-2): 183-92, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17196264
15.
Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis: Dose-Dependent Expression and Improved Retinal Structure and Function.
Hum Gene Ther
; 27(5): 376-89, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27036983
16.
Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice.
Mol Ther Methods Clin Dev
; 5: 16011, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27626041
17.
Laser photocoagulation enhances adeno-associated viral vector transduction of mouse retina.
Hum Gene Ther Methods
; 25(1): 83-91, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24191872
18.
Preclinical safety evaluation of a recombinant AAV8 vector for X-linked retinoschisis after intravitreal administration in rabbits.
Hum Gene Ther Clin Dev
; 25(4): 202-11, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211193
19.
Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.
PLoS One
; 7(5): e35865, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563472
20.
Vasoinhibin gene transfer by adenoassociated virus type 2 protects against VEGF- and diabetes-induced retinal vasopermeability.
Invest Ophthalmol Vis Sci
; 52(12): 8944-50, 2011 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22003113