Detalhe da pesquisa
1.
The ketone body ß-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-ß oligomer-induced inflammation in human microglia.
FASEB J
; 37(11): e23261, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878335
2.
Dimethyl fumarate dose-dependently increases mitochondrial gene expression and function in muscle and brain of Friedreich's ataxia model mice.
Hum Mol Genet
; 29(24): 3954-3965, 2021 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33432356
3.
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern.
Environ Sci Technol
; 57(20): 7645-7665, 2023 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37157132
4.
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection.
Proc Natl Acad Sci U S A
; 116(49): 24819-24829, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740620
5.
Nonphagocytic Activation of NOX2 Is Implicated in Progressive Nonalcoholic Steatohepatitis During Aging.
Hepatology
; 72(4): 1204-1218, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31950520
6.
Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice.
J Biochem Mol Toxicol
; 35(10): e22876, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34369032
7.
Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules.
Hum Mol Genet
; 26(24): 4929-4936, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29040550
8.
Frataxin deficiency impairs mitochondrial biogenesis in cells, mice and humans.
Hum Mol Genet
; 26(14): 2627-2633, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444186
9.
Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans.
Hum Mol Genet
; 26(15): 2864-2873, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28460056
10.
Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition.
Pharmacol Res
; 137: 89-103, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290222
11.
p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.
J Biol Chem
; 291(24): 12575-12585, 2016 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27059956
12.
Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism.
Neurobiol Dis
; 100: 30-38, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28042097
13.
Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse.
Hum Mol Genet
; 24(10): 2848-60, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25652399
14.
Galectin-3 regulates inflammasome activation in cholestatic liver injury.
FASEB J
; 30(12): 4202-4213, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630169
15.
A descriptive pilot study of cytokine production following stimulation of ex-vivo whole blood with commercial therapeutic feline hydrolyzed diets in individual healthy immunotolerant cats.
BMC Vet Res
; 13(1): 297, 2017 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985721
16.
Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity.
J Neurosci
; 35(6): 2516-29, 2015 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25673846
17.
Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.
Hum Mol Genet
; 23(25): 6838-47, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25104852
18.
Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.
Hum Mol Genet
; 23(25): 6848-62, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25113747
19.
Lactate and Pyruvate Are Major Sources of Energy for Stallion Sperm with Dose Effects on Mitochondrial Function, Motility, and ROS Production.
Biol Reprod
; 95(2): 34, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27335066
20.
HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.
Hum Mol Genet
; 21(7): 1457-69, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22171070