Detalhe da pesquisa
1.
Blood and cerebellar abundance of ATXN3 splice variants in spinocerebellar ataxia type 3/Machado-Joseph disease.
Neurobiol Dis
; 193: 106456, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423193
2.
Altered retinal structure and function in Spinocerebellar ataxia type 3.
Neurobiol Dis
; 170: 105774, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35605759
3.
Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia type 3 disease protein.
Neurobiol Dis
; 137: 104697, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31783119
4.
Recent therapeutic prospects for Machado-Joseph disease.
Curr Opin Neurol
; 33(4): 519-526, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32657894
5.
In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3.
Mov Disord
; 35(10): 1774-1786, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32621646
6.
Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.
Hum Mol Genet
; 26(8): 1419-1431, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28158474
7.
Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.
Hum Mol Genet
; 24(1): 100-17, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25143392
8.
A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.
Hum Mol Genet
; 24(5): 1211-24, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320121
9.
Unbiased screen identifies aripiprazole as a modulator of abundance of the polyglutamine disease protein, ataxin-3.
Brain
; 139(11): 2891-2908, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645800
10.
Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.
Neurobiol Dis
; 82: 281-288, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26141599
11.
Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.
Mol Ther
; 21(10): 1909-18, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23820820
12.
Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Mol Ther
; 21(10): 1898-908, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23765441
13.
Regional and age-dependent changes in ubiquitination in cellular and mouse models of spinocerebellar ataxia type 3.
Front Mol Neurosci
; 16: 1154203, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122622
14.
Regional and age-dependent changes in ubiquitination in cellular and mouse models of Spinocerebellar ataxia type 3.
bioRxiv
; 2023 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36891289
15.
Tissue-Specific Vulnerability to Apoptosis in Machado-Joseph Disease.
Cells
; 12(10)2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37408238
16.
Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3.
Dis Model Mech
; 16(9)2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37664882
17.
Sleep Alterations in a Mouse Model of Spinocerebellar Ataxia Type 3.
Cells
; 11(19)2022 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36231095
18.
Increased transcript diversity: novel splicing variants of Machado-Joseph disease gene (ATXN3).
Neurogenetics
; 11(2): 193-202, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19714377
19.
Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products.
Neurobiol Dis
; 40(1): 163-76, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20510362
20.
The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina.
Cell Rep
; 33(6): 108360, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33176149