Detalhe da pesquisa
1.
Miniproteins as a Powerful Modality in Drug Development.
Trends Biochem Sci
; 45(4): 332-346, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014389
2.
Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice.
Proc Natl Acad Sci U S A
; 109(19): 7487-92, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529362
3.
CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect.
bioRxiv
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712232
4.
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med
; 14(645): eabn0402, 2022 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584229
5.
Mammalian Surface Display Screening of Diverse Cystine-Dense Peptide Libraries for Difficult-to-Drug Targets.
Methods Mol Biol
; 2070: 363-396, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625107
6.
A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.
J Mol Biol
; 432(14): 3989-4009, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32304700
7.
Publisher Correction: Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets.
Nat Commun
; 9(1): 1072, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523778
8.
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets.
Nat Commun
; 8(1): 2244, 2017 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269835
9.
Surveying the landscape of Huntington's disease mechanisms, measurements, and medicines.
J Huntingtons Dis
; 2(4): 405-36, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25062729
10.
In vivo identification of therapeutic constructs from pooled candidates in HD model mice.
J Huntingtons Dis
; 2(4): 437-41, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25062730
11.
Huntington's disease: can mice lead the way to treatment?
Neuron
; 69(3): 423-35, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21315254