Detalhe da pesquisa
1.
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Hum Mol Genet
; 26(6): 1115-1132, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104789
2.
Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease.
BMC Biol
; 16(1): 58, 2018 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945611
3.
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.
Hum Mol Genet
; 25(17): 3654-3675, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378694
4.
BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep.
Neuron
; 111(22): 3604-3618.e11, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657440
5.
DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease.
Front Cell Neurosci
; 14: 590569, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33250715