Detalhe da pesquisa
1.
Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration.
J Pharmacol Exp Ther
; 351(3): 527-37, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232192
2.
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.
Nat Chem Biol
; 7(1): 41-50, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21113169
3.
Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys.
Drug Metab Dispos
; 38(4): 600-5, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071453
4.
Species-dependent serum interference in a sandwich ELISA for Apo2L/TRAIL.
J Immunol Methods
; 320(1-2): 58-69, 2007 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17280683
5.
Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.
JCI Insight
; 2(7): e90111, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28405610
6.
Characterization of a sensitive mouse Aß40 PD biomarker assay for Alzheimer's disease drug development in wild-type mice.
Bioanalysis
; 8(10): 1067-75, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27094761
7.
Substrate capacity considerations in developing kinase assays.
Assay Drug Dev Technol
; 2(2): 131-40, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15165509
8.
Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys.
MAbs
; 5(6): 896-903, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492343
9.
Micro-volume wall-less immunoassays using patterned planar plates.
Lab Chip
; 13(7): 1342-50, 2013 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23380873
10.
A case study on Sema3E-Fc aggregation and assay-dependent differences in quantitation.
Bioanalysis
; 4(6): 703-11, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22452261
11.
Subcutaneous bioavailability of therapeutic antibodies as a function of FcRn binding affinity in mice.
MAbs
; 4(1): 101-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22327433
12.
Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration.
Invest Ophthalmol Vis Sci
; 53(10): 6628-37, 2012 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22930722
13.
Evaluation of heterophilic antibody blocking agents in reducing false positive interference in immunoassays for IL-17AA, IL-17FF, and IL-17AF.
J Immunol Methods
; 362(1-2): 70-81, 2010 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833179
14.
Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study.
J Immunol Methods
; 345(1-2): 17-28, 2009 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345224
15.
Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.
Blood
; 110(12): 3959-67, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17687108
16.
Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood
; 108(9): 3103-11, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16840730