Detalhe da pesquisa
1.
Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype.
Hum Mol Genet
; 28(1): 105-123, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30239717
2.
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.
Mol Ther
; 25(11): 2546-2560, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28807567
3.
Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8.
Biotechnol Bioeng
; 113(12): 2712-2724, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259396
4.
Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice.
Mol Ther
; 23(1): 7-16, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25095892
5.
Repair of rhodopsin mRNA by spliceosome-mediated RNA trans-splicing: a new approach for autosomal dominant retinitis pigmentosa.
Mol Ther
; 23(5): 918-930, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25619725
6.
Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina.
Mol Ther Methods Clin Dev
; 31: 101107, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37868206
7.
Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models.
Sci Adv
; 8(42): eabm4295, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36260685
8.
Substantial restoration of night vision in adult mice with congenital stationary night blindness.
Mol Ther Methods Clin Dev
; 22: 15-25, 2021 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34401402
9.
Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness.
Invest Ophthalmol Vis Sci
; 62(3): 24, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33729473
10.
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates.
Commun Biol
; 4(1): 125, 2021 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504896
11.
Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery.
Methods Mol Biol
; 1715: 225-238, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188517
12.
Noninvasive gene delivery to foveal cones for vision restoration.
JCI Insight
; 3(2)2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367457
13.
Red-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.
EMBO Mol Med
; 8(11): 1248-1264, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27679671
14.
A single intravenous AAV9 injection mediates bilateral gene transfer to the adult mouse retina.
PLoS One
; 8(4): e61618, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23613884