Detalhe da pesquisa
1.
Hydrophobicity of Lipid-Conjugated siRNAs Predicts Productive Loading to Small Extracellular Vesicles.
Mol Ther
; 26(6): 1520-1528, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29699940
2.
Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles.
Mol Ther
; 26(8): 1973-1982, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29937418
3.
Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity.
Mol Ther
; 26(12): 2838-2847, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341012
4.
Visualization of self-delivering hydrophobically modified siRNA cellular internalization.
Nucleic Acids Res
; 45(1): 15-25, 2017 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899655
5.
Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing.
Mol Ther
; 24(10): 1836-1847, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27506293
6.
A novel function for fragile X mental retardation protein in translational activation.
PLoS Biol
; 7(1): e16, 2009 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19166269
7.
Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains.
Brain Commun
; 4(6): fcac248, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458209
8.
The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer.
Nucleic Acids Res
; 36(15): 4902-12, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18653529
9.
Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition.
iScience
; 16: 230-241, 2019 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31195240
10.
Loading of Extracellular Vesicles with Hydrophobically Modified siRNAs.
Methods Mol Biol
; 1740: 199-214, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29388146
11.
Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin.
Cell Rep
; 24(10): 2553-2560.e5, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30184490
12.
Loading of Extracellular Vesicles with Chemically Stabilized Hydrophobic siRNAs for the Treatment of Disease in the Central Nervous System.
Bio Protoc
; 7(20)2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28868334
13.
A High-throughput Assay for mRNA Silencing in Primary Cortical Neurons in vitro with Oligonucleotide Therapeutics.
Bio Protoc
; 7(16)2017 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28966945
14.
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles
; 5: 32570, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27863537
15.
Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain.
Mol Ther Nucleic Acids
; 4: e266, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26623938
16.
Glucocorticoid receptor ligands modulate Cardiovirus encephalomyocarditis virus internal ribosome entry site activity.
Assay Drug Dev Technol
; 11(6): 355-66, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23906347
17.
Identification of cardiac glycoside molecules as inhibitors of c-Myc IRES-mediated translation.
J Biomol Screen
; 18(4): 407-19, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150017
18.
Latent hit series hidden in high-throughput screening data.
J Med Chem
; 55(3): 1161-70, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22185196
19.
Multiplexed reporter gene assays: monitoring the cell viability and the compound kinetics on luciferase activity.
J Biomol Screen
; 16(7): 786-93, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21693766
20.
Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly.
Mol Biol Cell
; 20(1): 428-37, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19005212