Pesquisa | BVS Violência e Saúde

1.

The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation.

Gatsiou, Aikaterini; Tual-Chalot, Simon; Napoli, Matteo; Ortega-Gomez, Almudena; Regen, Tommy; Badolia, Rachit; Cesarini, Valeriana; Garcia-Gonzalez, Claudia; Chevre, Raphael; Ciliberti, Giorgia; Silvestre-Roig, Carlos; Martini, Maurizio; Hoffmann, Jedrzej; Hamouche, Rana; Visker, Joseph R; Diakos, Nikolaos; Wietelmann, Astrid; Silvestris, Domenico Alessandro; Georgiopoulos, Georgios; Moshfegh, Ali; Schneider, Andre; Chen, Wei; Guenther, Stefan; Backs, Johannes; Kwak, Shin; Selzman, Craig H; Stamatelopoulos, Kimon; Rose-John, Stefan; Trautwein, Christian; Spyridopoulos, Ioakim; Braun, Thomas; Waisman, Ari; Gallo, Angela; Drakos, Stavros G; Dimmeler, Stefanie; Sperandio, Markus; Soehnlein, Oliver; Stellos, Konstantinos.

Immunity ; 56(5): 979-997.e11, 2023 05 09.

Artigo em Inglês | MEDLINE | ID: mdl-37100060

2.

Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis.

Tamiato, Anita; Tombor, Lukas S; Fischer, Ariane; Muhly-Reinholz, Marion; Vanicek, Leah Rebecca; Togru, Büsra Nur; Neitz, Jessica; Glaser, Simone Franziska; Merten, Maximilian; Rodriguez Morales, David; Kwon, Jeonghyeon; Klatt, Stephan; Schumacher, Bianca; Günther, Stefan; Abplanalp, Wesley T; John, David; Fleming, Ingrid; Wettschureck, Nina; Dimmeler, Stefanie; Luxán, Guillermo.

Circ Res ; 134(10): 1240-1255, 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38563133

3.

Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia.

de Oliveira Freitas Machado, Camila; Schafranek, Michal; Brüggemann, Mirko; Hernández Cañás, María Clara; Keller, Mario; Di Liddo, Antonella; Brezski, Andre; Blümel, Nicole; Arnold, Benjamin; Bremm, Anja; Wittig, Ilka; Jaé, Nicolas; McNicoll, François; Dimmeler, Stefanie; Zarnack, Kathi; Müller-McNicoll, Michaela.

Nucleic Acids Res ; 51(2): 870-890, 2023 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-36620874

4.

CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes.

Zhu, Chaonan; Baumgarten, Nina; Wu, Meiqian; Wang, Yue; Das, Arka Provo; Kaur, Jaskiran; Ardakani, Fatemeh Behjati; Duong, Thanh Thuy; Pham, Minh Duc; Duda, Maria; Dimmeler, Stefanie; Yuan, Ting; Schulz, Marcel H; Krishnan, Jaya.

Hum Genomics ; 17(1): 69, 2023 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-37491351

5.

Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses.

Heumüller, Andreas W; Jones, Alisha N; Mourão, André; Klangwart, Marius; Shi, Chenyue; Wittig, Ilka; Fischer, Ariane; Muhly-Reinholz, Marion; Buchmann, Giulia K; Dieterich, Christoph; Potente, Michael; Braun, Thomas; Grote, Phillip; Jaé, Nicolas; Sattler, Michael; Dimmeler, Stefanie.

Circ Res ; 130(1): 67-79, 2022 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-34789007

6.

The splicing-regulatory lncRNA NTRAS sustains vascular integrity.

Fouani, Youssef; Kirchhof, Luisa; Stanicek, Laura; Luxán, Guillermo; Heumüller, Andreas W; Knau, Andrea; Fischer, Ariane; Devraj, Kavi; John, David; Neumann, Philipp; Bindereif, Albrecht; Boon, Reinier A; Liebner, Stefan; Wittig, Ilka; Mogler, Carolin; Karimova, Madina; Dimmeler, Stefanie; Jaé, Nicolas.

EMBO Rep ; 23(6): e54157, 2022 06 07.

Artigo em Inglês | MEDLINE | ID: mdl-35527520

7.

[Heart and blood: clonal hematopoiesis]. / Herz und Blut: klonale Hämatopoese.

Dimmeler, Stefanie; Zeiher, Andreas.

Herz ; 49(2): 105-110, 2024 Mar.

Artigo em Alemão | MEDLINE | ID: mdl-38424288

8.

Mosaic loss of Y chromosome in monocytes is associated with lower survival after transcatheter aortic valve replacement.

Mas-Peiro, Silvia; Abplanalp, Wesley T; Rasper, Tina; Berkowitsch, Alexander; Leistner, David M; Dimmeler, Stefanie; Zeiher, Andreas M.

Eur Heart J ; 44(21): 1943-1952, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36932691

9.

Cardiomyocyte hyperplasia and immaturity but not hypertrophy are characteristic features of patients with RASopathies.

Drenckhahn, Jörg-Detlef; Nicin, Luka; Akhouaji, Sara; Krück, Svenja; Blank, Anna Eva; Schänzer, Anne; Yörüker, Uygar; Jux, Christian; Tombor, Lukas; Abplanalp, Wesley; John, David; Zeiher, Andreas M; Dimmeler, Stefanie; Rupp, Stefan.

J Mol Cell Cardiol ; 178: 22-35, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36948385

10.

Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure.

Schierwagen, Robert; Gu, Wenyi; Brieger, Angela; Brüne, Bernhard; Ciesek, Sandra; Dikic, Ivan; Dimmeler, Stefanie; Geisslinger, Gerd; Greten, Florian R; Hermann, Eva; Hildt, Eberhard; Kempf, Volkhard A J; Klein, Sabine; Koch, Ina; Mühl, Heiko; Müller, Volker; Peiffer, Kai-Henrik; Kestner, Roxane-Isabelle; Piiper, Albrecht; Rohde, Gernot; Scholich, Klaus; Schulz, Marcel H; Storf, Holger; Toptan, Tuna; Vasa-Nicotera, Mariuca; Vehreschild, Maria J G T; Weigert, Andreas; Wild, Peter J; Zeuzem, Stefan; Engelmann, Cornelius; Schaefer, Liliana; Welsch, Christoph; Trebicka, Jonel.

Am J Physiol Cell Physiol ; 325(1): C129-C140, 2023 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-37273239

11.

Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure.

Abplanalp, Wesley Tyler; Cremer, Sebastian; John, David; Hoffmann, Jedrzej; Schuhmacher, Bianca; Merten, Maximillian; Rieger, Michael A; Vasa-Nicotera, Mariuca; Zeiher, Andreas M; Dimmeler, Stefanie.

Circ Res ; 128(2): 216-228, 2021 01 22.

Artigo em Inglês | MEDLINE | ID: mdl-33155517

12.

The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition.

Glaser, Simone F; Heumüller, Andreas W; Tombor, Lukas; Hofmann, Patrick; Muhly-Reinholz, Marion; Fischer, Ariane; Günther, Stefan; Kokot, Karoline E; Hassel, David; Kumar, Sandeep; Jo, Hanjoong; Boon, Reinier A; Abplanalp, Wesley; John, David; Boeckel, Jes-Niels; Dimmeler, Stefanie.

Proc Natl Acad Sci U S A ; 117(8): 4180-4187, 2020 02 25.

Artigo em Inglês | MEDLINE | ID: mdl-32034099

13.

Single-cell technologies to decipher cardiovascular diseases.

Abplanalp, Wesley Tyler; Tucker, Nathan; Dimmeler, Stefanie.

Eur Heart J ; 43(43): 4536-4547, 2022 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-35265972

14.

Single Nuclei Sequencing Reveals Novel Insights Into the Regulation of Cellular Signatures in Children With Dilated Cardiomyopathy.

Nicin, Luka; Abplanalp, Wesley T; Schänzer, Anne; Sprengel, Anke; John, David; Mellentin, Hannah; Tombor, Lukas; Keuper, Matthias; Ullrich, Evelyn; Klingel, Karin; Dettmeyer, Reinhard B; Hoffmann, Jedrzej; Akintuerk, Hakan; Jux, Christian; Schranz, Dietmar; Zeiher, Andreas M; Rupp, Stefan; Dimmeler, Stefanie.

Circulation ; 143(17): 1704-1719, 2021 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-33618539

15.

Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function.

Bibli, Sofia-Iris; Hu, Jiong; Looso, Mario; Weigert, Andreas; Ratiu, Corina; Wittig, Janina; Drekolia, Maria Kyriaki; Tombor, Lukas; Randriamboavonjy, Voahanginirina; Leisegang, Matthias S; Goymann, Philipp; Delgado Lagos, Fredy; Fisslthaler, Beate; Zukunft, Sven; Kyselova, Anastasia; Justo, Alberto Fernando Oliveira; Heidler, Juliana; Tsilimigras, Diamantis; Brandes, Ralf P; Dimmeler, Stefanie; Papapetropoulos, Andreas; Knapp, Stefan; Offermanns, Stefan; Wittig, Ilka; Nishimura, Stephen L; Sigala, Fragiska; Fleming, Ingrid.

Circulation ; 143(9): 935-948, 2021 03 02.

Artigo em Inglês | MEDLINE | ID: mdl-33307764

16.

Why is endothelial resilience key to maintain cardiac health?

Tombor, Lukas S; Dimmeler, Stefanie.

Basic Res Cardiol ; 117(1): 35, 2022 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-35834003

17.

Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.

Kokot, Karoline E; Kneuer, Jasmin M; John, David; Rebs, Sabine; Möbius-Winkler, Maximilian N; Erbe, Stephan; Müller, Marion; Andritschke, Michael; Gaul, Susanne; Sheikh, Bilal N; Haas, Jan; Thiele, Holger; Müller, Oliver J; Hille, Susanne; Leuschner, Florian; Dimmeler, Stefanie; Streckfuss-Bömeke, Katrin; Meder, Benjamin; Laufs, Ulrich; Boeckel, Jes-Niels.

Basic Res Cardiol ; 117(1): 32, 2022 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-35737129

18.

Noncoding RNAs in Vascular Diseases.

Jaé, Nicolas; Dimmeler, Stefanie.

Circ Res ; 126(9): 1127-1145, 2020 04 24.

Artigo em Inglês | MEDLINE | ID: mdl-32324505

19.

Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations.

Assmus, Birgit; Cremer, Sebastian; Kirschbaum, Klara; Culmann, David; Kiefer, Katharina; Dorsheimer, Lena; Rasper, Tina; Abou-El-Ardat, Khalil; Herrmann, Eva; Berkowitsch, Alexander; Hoffmann, Jedrzej; Seeger, Florian; Mas-Peiro, Silvia; Rieger, Michael A; Dimmeler, Stefanie; Zeiher, Andreas M.

Eur Heart J ; 42(3): 257-265, 2021 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-33241418

20.

Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants.

Wagner, Julian U G; Bojkova, Denisa; Shumliakivska, Mariana; Luxán, Guillermo; Nicin, Luka; Aslan, Galip S; Milting, Hendrik; Kandler, Joshua D; Dendorfer, Andreas; Heumueller, Andreas W; Fleming, Ingrid; Bibli, Sofia-Iris; Jakobi, Tobias; Dieterich, Christoph; Zeiher, Andreas M; Ciesek, Sandra; Cinatl, Jindrich; Dimmeler, Stefanie.

Basic Res Cardiol ; 116(1): 42, 2021 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-34224022

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