Detalhe da pesquisa
1.
Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor.
Bioorg Med Chem Lett
; 107: 129769, 2024 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670537
2.
Preparation and evaluation of fenbendazole methyl-ß-cyclodextrin inclusion complexes.
BMC Vet Res
; 20(1): 214, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38769544
3.
Randomly Methylated ß-Cyclodextrin Inclusion Complex with Ketoconazole: Preparation, Characterization, and Improvement of Pharmacological Profiles.
Molecules
; 29(9)2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731409
4.
The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole.
Molecules
; 28(21)2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37959715
5.
Solubility and Pharmacokinetic Profile Improvement of Griseofulvin through Supercritical Carbon Dioxide-Assisted Complexation with HP-γ-Cyclodextrin.
Molecules
; 28(21)2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37959779
6.
Safety, Tolerability, and Pharmacokinetics of the Novel Hepatitis B Virus Expression Inhibitor GST-HG131 in Healthy Chinese Subjects: a First-in-Human Single- and Multiple-Dose Escalation Trial.
Antimicrob Agents Chemother
; 66(5): e0009422, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404074
7.
Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent.
Bioorg Med Chem Lett
; 71: 128824, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35636648
8.
Discovery and preclinical evaluations of JBD0131, a novel nitrodihydro-imidazooxazole anti-tuberculosis agent.
Bioorg Med Chem Lett
; 72: 128871, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35777718
9.
Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD).
Bioorg Med Chem Lett
; 66: 128734, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35436589
10.
Discovery and preclinical evaluations of WX-0593, a novel ALK inhibitor targeting crizotinib-resistant mutations.
Bioorg Med Chem Lett
; 66: 128730, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35421578
11.
Discovery and preclinical evaluations of GST-HG131, a novel HBV antigen inhibitor for the treatment of chronic hepatitis B infection.
Bioorg Med Chem Lett
; 75: 128977, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36089112
12.
Therapeutic Effect and Mechanisms of the Novel Monosulfactam 0073.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32718961
13.
Design, syntheses and evaluations of novel indole derivatives as orally selective estrogen receptor degraders (SERD).
Bioorg Med Chem Lett
; 30(22): 127601, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035677
14.
Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria.
Molecules
; 25(10)2020 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32456032
15.
Discovery and evaluation of novel nitrodihydroimidazooxazoles as promising anti-tuberculosis agents.
Bioorg Med Chem Lett
; 29(17): 2511-2515, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353295
16.
Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase.
Antimicrob Agents Chemother
; 60(10): 6271-80, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503647
17.
Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Bioorg Med Chem Lett
; 25(1): 75-82, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25466195
18.
Synthesis and biological evaluation of novel pyrrolidine acid analogs as potent dual PPARα/γ agonists.
Bioorg Med Chem Lett
; 25(6): 1196-205, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25686852
19.
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase.
Bioorg Med Chem Lett
; 24(24): 5683-5687, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467161
20.
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Bioorg Med Chem Lett
; 24(16): 3764-71, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25037916