Pesquisa | BVS Violência e Saúde

1.

SnapShot: Cell size control.

Futcher, Bruce; Kellogg, Douglas R.

Cell ; 187(11): 2896-2896.e1, 2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38788693

2.

Super-enhancers include classical enhancers and facilitators to fully activate gene expression.

Blayney, Joseph W; Francis, Helena; Rampasekova, Alexandra; Camellato, Brendan; Mitchell, Leslie; Stolper, Rosa; Cornell, Lucy; Babbs, Christian; Boeke, Jef D; Higgs, Douglas R; Kassouf, Mira.

Cell ; 186(26): 5826-5839.e18, 2023 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-38101409

3.

Sublethal cytochrome c release generates drug-tolerant persister cells.

Kalkavan, Halime; Chen, Mark J; Crawford, Jeremy C; Quarato, Giovanni; Fitzgerald, Patrick; Tait, Stephen W G; Goding, Colin R; Green, Douglas R.

Cell ; 185(18): 3356-3374.e22, 2022 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-36055199

4.

Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.

Piehl, Natalie; van Olst, Lynn; Ramakrishnan, Abhirami; Teregulova, Victoria; Simonton, Brooke; Zhang, Ziyang; Tapp, Emma; Channappa, Divya; Oh, Hamilton; Losada, Patricia M; Rutledge, Jarod; Trelle, Alexandra N; Mormino, Elizabeth C; Elahi, Fanny; Galasko, Douglas R; Henderson, Victor W; Wagner, Anthony D; Wyss-Coray, Tony; Gate, David.

Cell ; 185(26): 5028-5039.e13, 2022 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-36516855

5.

Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral T_reg cell differentiation.

Lin, Liangyu; Hu, Mingyuan; Li, Qing; Du, Liming; Lin, Li; Xue, Yueqing; Zheng, Fanjun; Wang, Fei; Liu, Keli; Wang, Yu; Ye, Jiayin; Jiang, Xu; Wang, Xuefeng; Wang, Jiaqi; Zhai, Jingjie; Liu, Benming; Xie, Hongzhen; You, Yanqin; Wang, Jinyong; Kong, Xiangyin; Feng, Dechun; Green, Douglas R; Shi, Yufang; Wang, Ying.

Nat Immunol ; 25(1): 54-65, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38062135

6.

The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment.

Rodriguez, Henry; Zenklusen, Jean Claude; Staudt, Louis M; Doroshow, James H; Lowy, Douglas R.

Cell ; 184(7): 1661-1670, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33798439

7.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Puleston, Daniel J; Baixauli, Francesc; Sanin, David E; Edwards-Hicks, Joy; Villa, Matteo; Kabat, Agnieszka M; Kaminski, Marcin M; Stanckzak, Michal; Weiss, Hauke J; Grzes, Katarzyna M; Piletic, Klara; Field, Cameron S; Corrado, Mauro; Haessler, Fabian; Wang, Chao; Musa, Yaarub; Schimmelpfennig, Lena; Flachsmann, Lea; Mittler, Gerhard; Yosef, Nir; Kuchroo, Vijay K; Buescher, Joerg M; Balabanov, Stefan; Pearce, Edward J; Green, Douglas R; Pearce, Erika L.

Cell ; 184(16): 4186-4202.e20, 2021 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-34216540

8.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

Zhang, Ting; Yin, Chaoran; Boyd, David F; Quarato, Giovanni; Ingram, Justin P; Shubina, Maria; Ragan, Katherine B; Ishizuka, Takumi; Crawford, Jeremy Chase; Tummers, Bart; Rodriguez, Diego A; Xue, Jia; Peri, Suraj; Kaiser, William J; López, Carolina B; Xu, Yan; Upton, Jason W; Thomas, Paul G; Green, Douglas R; Balachandran, Siddharth.

Cell ; 180(6): 1115-1129.e13, 2020 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-32200799

9.

The Coming Decade of Cell Death Research: Five Riddles.

Green, Douglas R.

Cell ; 177(5): 1094-1107, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-31100266

10.

Autophagy-Independent Functions of the Autophagy Machinery.

Galluzzi, Lorenzo; Green, Douglas R.

Cell ; 177(7): 1682-1699, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31199916

11.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Heckmann, Bradlee L; Teubner, Brett J W; Tummers, Bart; Boada-Romero, Emilio; Harris, Lacie; Yang, Mao; Guy, Clifford S; Zakharenko, Stanislav S; Green, Douglas R.

Cell ; 178(3): 536-551.e14, 2019 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-31257024

12.

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.

Rojas, Federico; Silvester, Eleanor; Young, Julie; Milne, Rachel; Tettey, Mabel; Houston, Douglas R; Walkinshaw, Malcolm D; Pérez-Pi, Irene; Auer, Manfred; Denton, Helen; Smith, Terry K; Thompson, Joanne; Matthews, Keith R.

Cell ; 176(1-2): 306-317.e16, 2019 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-30503212

13.

An Element of Life.

Green, Douglas R.

Cell ; 172(3): 389-390, 2018 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-29373826

14.

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

Cunha, Larissa D; Yang, Mao; Carter, Robert; Guy, Clifford; Harris, Lacie; Crawford, Jeremy C; Quarato, Giovanni; Boada-Romero, Emilio; Kalkavan, Halime; Johnson, Michael D L; Natarajan, Sivaraman; Turnis, Meghan E; Finkelstein, David; Opferman, Joseph T; Gawad, Charles; Green, Douglas R.

Cell ; 175(2): 429-441.e16, 2018 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-30245008

15.

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.

Daigle, Tanya L; Madisen, Linda; Hage, Travis A; Valley, Matthew T; Knoblich, Ulf; Larsen, Rylan S; Takeno, Marc M; Huang, Lawrence; Gu, Hong; Larsen, Rachael; Mills, Maya; Bosma-Moody, Alice; Siverts, La' Akea; Walker, Miranda; Graybuck, Lucas T; Yao, Zizhen; Fong, Olivia; Nguyen, Thuc Nghi; Garren, Emma; Lenz, Garreck H; Chavarha, Mariya; Pendergraft, Julie; Harrington, James; Hirokawa, Karla E; Harris, Julie A; Nicovich, Philip R; McGraw, Medea J; Ollerenshaw, Douglas R; Smith, Kimberly A; Baker, Christopher A; Ting, Jonathan T; Sunkin, Susan M; Lecoq, Jérôme; Lin, Michael Z; Boyden, Edward S; Murphy, Gabe J; da Costa, Nuno M; Waters, Jack; Li, Lu; Tasic, Bosiljka; Zeng, Hongkui.

Cell ; 174(2): 465-480.e22, 2018 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-30007418

16.

Loss of CD4⁺ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

West, Erin E; Merle, Nicolas S; Kaminski, Marcin M; Palacios, Gustavo; Kumar, Dhaneshwar; Wang, Luopin; Bibby, Jack A; Overdahl, Kirsten; Jarmusch, Alan K; Freeley, Simon; Lee, Duck-Yeon; Thompson, J Will; Yu, Zu-Xi; Taylor, Naomi; Sitbon, Marc; Green, Douglas R; Bohrer, Andrea; Mayer-Barber, Katrin D; Afzali, Behdad; Kazemian, Majid; Scholl-Buergi, Sabine; Karall, Daniela; Huemer, Martina; Kemper, Claudia.

Immunity ; 56(9): 2036-2053.e12, 2023 09 12.

Artigo em Inglês | MEDLINE | ID: mdl-37572656

17.

The clearance of dead cells by efferocytosis.

Boada-Romero, Emilio; Martinez, Jennifer; Heckmann, Bradlee L; Green, Douglas R.

Nat Rev Mol Cell Biol ; 21(7): 398-414, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32251387

18.

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences.

Gong, Yi-Nan; Guy, Cliff; Olauson, Hannes; Becker, Jan Ulrich; Yang, Mao; Fitzgerald, Patrick; Linkermann, Andreas; Green, Douglas R.

Cell ; 169(2): 286-300.e16, 2017 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-28388412

19.

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

Moretti, Julien; Roy, Soumit; Bozec, Dominique; Martinez, Jennifer; Chapman, Jessica R; Ueberheide, Beatrix; Lamming, Dudley W; Chen, Zhijian J; Horng, Tiffany; Yeretssian, Garabet; Green, Douglas R; Blander, J Magarian.

Cell ; 171(4): 809-823.e13, 2017 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-29056340

20.

A BH3 Mimetic for Killing Cancer Cells.

Green, Douglas R.

Cell ; 165(7): 1560, 2016 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-27315468

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SnapShot: Cell size control.

Super-enhancers include classical enhancers and facilitators to fully activate gene expression.

Sublethal cytochrome c release generates drug-tolerant persister cells.

Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.

Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral T_reg cell differentiation.

The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

The Coming Decade of Cell Death Research: Five Riddles.

Autophagy-Independent Functions of the Autophagy Machinery.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.

An Element of Life.

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.

Loss of CD4⁺ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

The clearance of dead cells by efferocytosis.

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences.

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

A BH3 Mimetic for Killing Cancer Cells.