Pesquisa | BVS Violência e Saúde

1.

TCR-mimic bispecific antibodies to target the HIV-1 reservoir.

Sengupta, Srona; Board, Nathan L; Wu, Fengting; Moskovljevic, Milica; Douglass, Jacqueline; Zhang, Josephine; Reinhold, Bruce R; Duke-Cohan, Jonathan; Yu, Jeanna; Reed, Madison C; Tabdili, Yasmine; Azurmendi, Aitana; Fray, Emily J; Zhang, Hao; Hsiue, Emily Han-Chung; Jenike, Katharine; Ho, Ya-Chi; Gabelli, Sandra B; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin; Siliciano, Janet D; Sadegh-Nasseri, Scheherazade; Reinherz, Ellis L; Siliciano, Robert F.

Proc Natl Acad Sci U S A ; 119(15): e2123406119, 2022 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-35394875

2.

Targeting loss of heterozygosity for cancer-specific immunotherapy.

Hwang, Michael S; Mog, Brian J; Douglass, Jacqueline; Pearlman, Alexander H; Hsiue, Emily Han-Chung; Paul, Suman; DiNapoli, Sarah R; Konig, Maximilian F; Pardoll, Drew M; Gabelli, Sandra B; Bettegowda, Chetan; Papadopoulos, Nickolas; Vogelstein, Bert; Zhou, Shibin; Kinzler, Kenneth W.

Proc Natl Acad Sci U S A ; 118(12)2021 03 23.

Artigo em Inglês | MEDLINE | ID: mdl-33731480

3.

An engineered antibody fragment targeting mutant ß-catenin via major histocompatibility complex I neoantigen presentation.

Miller, Michelle S; Douglass, Jacqueline; Hwang, Michael S; Skora, Andrew D; Murphy, Michael; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.

J Biol Chem ; 294(50): 19322-19334, 2019 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-31690625

4.

The microbiome and breast cancer: a review.

Chen, Jennifer; Douglass, Jacqueline; Prasath, Vishnu; Neace, Meghan; Atrchian, Siavash; Manjili, Masoud H; Shokouhi, Shervin; Habibi, Mehran.

Breast Cancer Res Treat ; 178(3): 493-496, 2019 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-31456069

5.

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes.

Skora, Andrew D; Douglass, Jacqueline; Hwang, Michael S; Tam, Ada J; Blosser, Richard L; Gabelli, Sandra B; Cao, Jianhong; Diaz, Luis A; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin.

Proc Natl Acad Sci U S A ; 112(32): 9967-72, 2015 Aug 11.

Artigo em Inglês | MEDLINE | ID: mdl-26216968

6.

Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.

Wright, Katharine M; DiNapoli, Sarah R; Miller, Michelle S; Aitana Azurmendi, P; Zhao, Xiaowei; Yu, Zhiheng; Chakrabarti, Mayukh; Shi, WuXian; Douglass, Jacqueline; Hwang, Michael S; Hsiue, Emily Han-Chung; Mog, Brian J; Pearlman, Alexander H; Paul, Suman; Konig, Maximilian F; Pardoll, Drew M; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.

Nat Commun ; 14(1): 5063, 2023 08 21.

Artigo em Inglês | MEDLINE | ID: mdl-37604828

7.

Identifying protein kinase target preferences using mass spectrometry.

Douglass, Jacqueline; Gunaratne, Ruwan; Bradford, Davis; Saeed, Fahad; Hoffert, Jason D; Steinbach, Peter J; Knepper, Mark A; Pisitkun, Trairak.

Am J Physiol Cell Physiol ; 303(7): C715-27, 2012 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-22723110

8.

Mutation-guided therapeutics.

Douglass, Jacqueline.

Science ; 376(6589): 147, 2022 04 08.

Artigo em Inglês | MEDLINE | ID: mdl-35389812

9.

Valid-NEO: A Multi-Omics Platform for Neoantigen Detection and Quantification from Limited Clinical Samples.

Terai, Yuri Laguna; Huang, Chun; Wang, Baoli; Kang, Xiaonan; Han, Jing; Douglass, Jacqueline; Hsiue, Emily Han-Chung; Zhang, Ming; Purohit, Raj; deSilva, Taylor; Wang, Qing.

Cancers (Basel) ; 14(5)2022 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-35267551

10.

Targeting public neoantigens for cancer immunotherapy.

Pearlman, Alexander H; Hwang, Michael S; Konig, Maximilian F; Hsiue, Emily Han-Chung; Douglass, Jacqueline; DiNapoli, Sarah R; Mog, Brian J; Bettegowda, Chetan; Pardoll, Drew M; Gabelli, Sandra B; Papadopoulos, Nicholas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin.

Nat Cancer ; 2(5): 487-497, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34676374

11.

Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.

Hwang, Michael S; Miller, Michelle S; Thirawatananond, Puchong; Douglass, Jacqueline; Wright, Katharine M; Hsiue, Emily Han-Chung; Mog, Brian J; Aytenfisu, Tihitina Y; Murphy, Michael B; Aitana Azurmendi, P; Skora, Andrew D; Pearlman, Alexander H; Paul, Suman; DiNapoli, Sarah R; Konig, Maximilian F; Bettegowda, Chetan; Pardoll, Drew M; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin; Gabelli, Sandra B.

Nat Commun ; 12(1): 5271, 2021 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-34489470

12.

TCR ß chain-directed bispecific antibodies for the treatment of T cell cancers.

Paul, Suman; Pearlman, Alexander H; Douglass, Jacqueline; Mog, Brian J; Hsiue, Emily Han-Chung; Hwang, Michael S; DiNapoli, Sarah R; Konig, Maximilian F; Brown, Patrick A; Wright, Katharine M; Sur, Surojit; Gabelli, Sandra B; Li, Yana; Ghiaur, Gabriel; Pardoll, Drew M; Papadopoulos, Nickolas; Bettegowda, Chetan; Kinzler, Kenneth W; Zhou, Shibin; Vogelstein, Bert.

Sci Transl Med ; 13(584)2021 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-33649188

13.

Bispecific antibodies targeting mutant RAS neoantigens.

Douglass, Jacqueline; Hsiue, Emily Han-Chung; Mog, Brian J; Hwang, Michael S; DiNapoli, Sarah R; Pearlman, Alexander H; Miller, Michelle S; Wright, Katharine M; Azurmendi, P Aitana; Wang, Qing; Paul, Suman; Schaefer, Annika; Skora, Andrew D; Molin, Marco Dal; Konig, Maximilian F; Liu, Qiang; Watson, Evangeline; Li, Yana; Murphy, Michael B; Pardoll, Drew M; Bettegowda, Chetan; Papadopoulos, Nickolas; Gabelli, Sandra B; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin.

Sci Immunol ; 6(57)2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-33649101

14.

Targeting a neoantigen derived from a common TP53 mutation.

Hsiue, Emily Han-Chung; Wright, Katharine M; Douglass, Jacqueline; Hwang, Michael S; Mog, Brian J; Pearlman, Alexander H; Paul, Suman; DiNapoli, Sarah R; Konig, Maximilian F; Wang, Qing; Schaefer, Annika; Miller, Michelle S; Skora, Andrew D; Azurmendi, P Aitana; Murphy, Michael B; Liu, Qiang; Watson, Evangeline; Li, Yana; Pardoll, Drew M; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Gabelli, Sandra B; Zhou, Shibin.

Science ; 371(6533)2021 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-33649166

15.

Direct Detection and Quantification of Neoantigens.

Wang, Qing; Douglass, Jacqueline; Hwang, Michael S; Hsiue, Emily Han-Chung; Mog, Brian J; Zhang, Ming; Papadopoulos, Nickolas; Kinzler, Kenneth W; Zhou, Shibin; Vogelstein, Bert.

Cancer Immunol Res ; 7(11): 1748-1754, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31527070

16.

Concurrent Immune Checkpoint Inhibitors and Stereotactic Radiosurgery for Brain Metastases in Non-Small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma.

Chen, Linda; Douglass, Jacqueline; Kleinberg, Lawrence; Ye, Xiaobu; Marciscano, Ariel E; Forde, Patrick M; Brahmer, Julie; Lipson, Evan; Sharfman, William; Hammers, Hans; Naidoo, Jarushka; Bettegowda, Chetan; Lim, Michael; Redmond, Kristin J.

Int J Radiat Oncol Biol Phys ; 100(4): 916-925, 2018 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-29485071

17.

Author Correction: Targeting public neoantigens for cancer immunotherapy.

Pearlman, Alexander H; Hwang, Michael S; Konig, Maximilian F; Hsiue, Emily Han-Chung; Douglass, Jacqueline; DiNapoli, Sarah R; Mog, Brian J; Bettegowda, Chetan; Pardoll, Drew M; Gabelli, Sandra B; Papadopoulos, Nicholas; Kinzler, Kenneth W; Vogelstein, Bert; Zhou, Shibin.

Nat Cancer ; 2(8): 865-867, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-35122030

18.

Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy.

Perica, Karlo; Bieler, Joan Glick; Schütz, Christian; Varela, Juan Carlos; Douglass, Jacqueline; Skora, Andrew; Chiu, Yen Ling; Oelke, Mathias; Kinzler, Kenneth; Zhou, Shibin; Vogelstein, Bert; Schneck, Jonathan P.

ACS Nano ; 9(7): 6861-71, 2015 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-26171764

19.

Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites.

Lo, Justin H; von Maltzahn, Geoffrey; Douglass, Jacqueline; Park, Ji-Ho; Sailor, Michael J; Ruoslahti, Erkki; Bhatia, Sangeeta N.

J Mater Chem B ; 1(39): 5235-5240, 2013 Oct 21.

Artigo em Inglês | MEDLINE | ID: mdl-24177171

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