Detalhe da pesquisa
1.
Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes.
Bioorg Med Chem
; 65: 116782, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512484
2.
CRISPR-Knockout Screen Identifies Dmap1 as a Regulator of Chemically Induced Reprogramming and Differentiation of Cardiac Progenitors.
Stem Cells
; 37(7): 958-972, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30932271
3.
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.
Proc Natl Acad Sci U S A
; 114(40): E8372-E8381, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916735
4.
High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.
J Mol Cell Cardiol
; 127: 204-214, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30597148
5.
Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.
Physiol Genomics
; 48(11): 771-784, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591124
6.
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity.
Nat Commun
; 15(1): 4529, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38806456
7.
Human skeletal muscle cells with a slow adhesion rate after isolation and an enhanced stress resistance improve function of ischemic hearts.
Mol Ther
; 20(1): 138-45, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22068427
8.
Epigenome editing of the CFTR-locus for treatment of cystic fibrosis.
J Cyst Fibros
; 21(1): 164-171, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049825
9.
Cellular antioxidant levels influence muscle stem cell therapy.
Mol Ther
; 18(10): 1865-73, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664528
10.
Prospective identification of myogenic endothelial cells in human skeletal muscle.
Nat Biotechnol
; 25(9): 1025-34, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17767154
11.
Applications of Functional Genomics for Drug Discovery.
SLAS Discov
; 25(8): 823-842, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32026742
12.
Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cells.
Sci Rep
; 10(1): 13575, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32782331
13.
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach.
Stem Cells Transl Med
; 9(1): 47-60, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31508905
14.
Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFß Inhibitors.
ChemMedChem
; 14(8): 810-822, 2019 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30768867
15.
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.
Cell Stem Cell
; 24(6): 895-907.e6, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930147
16.
Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.
ACS Chem Biol
; 12(1): 132-141, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28103692
17.
Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-ß Type 1 Receptor Kinase Inhibitor Induces Efficient Cardiac Differentiation.
Stem Cells Transl Med
; 5(2): 164-74, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26683871
18.
Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions.
Nat Biomed Eng
; 12016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28462012
19.
Human myogenic endothelial cells exhibit chondrogenic and osteogenic potentials at the clonal level.
J Orthop Res
; 31(7): 1089-95, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23553740
20.
Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history.
Tissue Eng Part A
; 18(11-12): 1101-8, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22280442