Severe Acute Respiratory Syndrome Coronavirus 2 P.2 Lineage Associated with Reinfection Case, Brazil, June-October 2020.

A 37-year-old healthcare worker from the northeastern region of Brazil experienced 2 clinical episodes of coronavirus disease. Infection with severe acute respiratory syndrome coronavirus 2 was confirmed by reverse transcription PCR in samples collected 116 days apart. Whole-genome sequencing revealed that the 2 infections were caused by the most prevalent lineage in Brazil, B.1.1.33, and the emerging lineage P.2. The first infection occurred in June 2020; Bayesian analysis suggests reinfection at some point during September 14-October 11, 2020, a few days before the second episode of coronavirus disease. Of note, P.2 corresponds to an emergent viral lineage in Brazil that contains the mutation E484K in the spike protein. The P.2 lineage was initially detected in the state of Rio de Janeiro, and since then it has been found throughout the country. Our findings suggest not only a reinfection case but also geographic dissemination of the emerging Brazil clade P.2.

Incidence of pressure injuries and risk factors in a paediatric surgical intensive care unit: a prospective cohort study.

OBJECTIVES: The aim of the study was to evaluate the incidence of, and risk factors for, the occurrence of pressure injuries (PIs) in a paediatric surgical intensive care unit (ICU). METHOD: This is a prospective cohort study of 153 children in the postoperative period. Patients were assessed daily by physical examination and data were collected. All independent variables were included in a logistic regression. RESULTS: The mean age of the cohort was 2 years, and the incidence of PI was 15.7%. According to the Braden Q Scale, 58.2% of patients were at high risk of developing PI; 79.3% of PIs were related to immobility and 69.0% were at stage 1. Risk factors were ICU length of stay and the number of medical devices used. CONCLUSION: The incidence of PI was high because patients were mostly at a considerable risk of developing a PI. PI was associated with several factors, especially length of ICU stay and number of devices, both of which are indirect indicators of the severity of patient condition and healthcare costs.

Screening method of mildronate and over 300 doping agents by reversed-phase liquid chromatography-high resolution mass spectrometry.

Considering the huge amount of substances associated with athletic performance improvement, current doping control analysis requires a comprehensive screening method, which leads to the detection of prohibited substances of different physico-chemical properties. This comprehensiveness associated with instrumental approaches based on high resolution mass spectrometry has allowed the development of extremely sensitive and selective detection methods. Furthermore, it is desirable the method to be simple, fast and straightforward. Mildronate is a highly polar quaternary amine, classified as metabolic modulator by the World Anti-Doping Agency (WADA). The inclusion of mildronate in the screening strategy is a challenge considering its singular physicochemical properties, compared to numerous doping agents of low and medium polarity. For this purpose, a method combining solid-phase extraction (SPE) and dilute-and-shoot approach has been developed and validated, allowing the detection of mildronate and other 332 prohibited substances. In the sample preparation protocol, the enzymatic deconjugation step and SPE conditions were stressed to enable the recovery of mildronate without jeopardizing the detection of other doping agents. The C18/18% SPE cartridge without any type of ionic interaction, associated with the dilute-and-shoot approach proved to be effective for all monitored substances. The instrumental method employed was based on liquid chromatography using a reversed-phase column in a 12-minute gradient coupled to a high-resolution mass spectrometry in full scan with positive and negative switching and fragmentation in the positive mode, for the most critical detection compounds. The performance of the method was evaluated regarding selectivity, precision, recovery, carry-over, limit of detection and stability, following the recommendations of WADA.

Risk factors for common mental disorders in health care workers in the city of Diamantina, state of Minas Gerais.

INTRODUCTION: The increased prevalence of mental health symptoms in primary care workers in recent years is a major cause of concern, and highlights the need to identify modifiable risk factors for mental health disorders in this population. OBJECTIVES: To analyze the prevalence of common mental disorders and associated factors in primary care workers in the city of Diamantina, state of Minas Gerais. METHODS: This was a cross-sectional, exploratory study involving 203 workers in different sectors of primary health care. Participants completed the Self-Report Questionnaire (20 item version), the Job Stress Scale (JSS), and a form with questions regarding sociodemographic factors, occupational characteristics, lifestyle and habits. RESULTS: The prevalence of common mental disorders in the sample was 20.2%. These disorders were significantly associated (p ≤ 0.05) with younger age, poor self-assessed health, poor sleep quality and physically demanding work. CONCLUSIONS: Poor working conditions may directly and indirectly affect the occurrence of mental health disorders by influencing lifestyle and habits. The restructuring of organizational norms, together with worker support policies, may positively contribute to the mental health of workers.

Workplace violence among municipal health care workers in Diamantina, Minas Gerais, Brazil, 2017.

BACKGROUND: Health care workers stand out in recent studies as a function of high rates of workplace violence. OBJECTIVE: To calculate the prevalence of workplace violence involving health care workers and associated factors. METHODS: Cross-sectional study with municipal health care workers in Diamantina, Minas Gerais, Brazil. Data were collected in interviews from December 2016 through March 2017. Variable workplace violence was considered as outcome on univariate and multivariate analysis. Descriptive and analytical statistical techniques were used (Poisson regression). RESULTS: The study population comprised 203 municipal health care workers (79% response rate). The prevalence of workplace violence was 40.4-47.9% for women and 22.0% for men. Occupational factors associated with violence were job satisfaction, support at work and psychological demands. CONCLUSION: The prevalence rates we found and associated factors point to the relevance of health protection policies targeting this category of workers which may contribute to mitigate the negative effects of violence on the health of workers and consequently on the quality of care delivery.

INTRODUÇÃO: Trabalhadores do setor saúde são destaques em estudos recentes pelas proporções significativas de vivência de violência no trabalho. OBJETIVO: Estimar a prevalência e os fatores associados à violência entre trabalhadores da saúde. MÉTODO: Estudo de corte transversal, realizado com trabalhadores municipais de saúde. A coleta de dados ocorreu de dezembro de 2016 a março de 2017, por meio de entrevistas a trabalhadores da saúde de Diamantina (MG). Para a análise, a variável violência no trabalho foi tratada como desfecho em análises bivariada e múltiplas. Foram utilizadas técnicas de estatística descritivas e analíticas (regressão de Poisson). RESULTADOS: Participaram da pesquisa 203 trabalhadores municipais de saúde (taxa de resposta de 79%). A prevalência de violência no trabalho foi de 40,4% no total, sendo de 47,9% entre as mulheres e de 22,0% entre os homens. Os fatores do trabalho associados à violência foram a satisfação com o trabalho, o baixo apoio e a alta demanda psicológica no trabalho. CONCLUSÃO: A prevalência evidenciada e as associações sugeridas direcionam para a necessidade de reformular e criar políticas de proteção à saúde dos trabalhadores da saúde de modo que amenize os possíveis efeitos dessa experiência na saúde do trabalhador e na qualidade do serviço prestado.

Prevalence of negative self-rated health and associated factors among healthcare workers in a Southeast Brazilian city. / Prevalência e fatores associados à autoavaliação negativa de saúde entre trabalhadores da rede municipal de saúde de Diamantina, Minas Gerais.

OBJECTIVE: to investigate the prevalence of negative self-rated health and associated factors among municipal health service workers in Diamantina, MG, Brazil. METHODS: this was a cross-sectional census study using Poisson regression. RESULTS: 203 health workers took part in the study, 70.9% were female, and 57.1% were up to 38 years old; prevalence of negative self-rated health was 28.6% (95%CI22.4;34.8); in the multivariate analysis, the following were associated with the outcome: being 39 years old or more (PR=1.56 - 95%CI1.01;2.40), monthly family income >3 minimum wages (PR=0.63 - 95%CI0.41;0.97), having another paid occupation (PR=0.55 - 95%CI0.34;0.89), poor sleep quality (PR=1.99 - 95%CI1.32;2.99), diagnosis of one disease (PR=2.33 - 95%CI1.13;4.81) or multiple diseases (PR=2.63 - 95%CI1.32;5.24), suffering aggression at work (PR=1.92 - 95%CI1.29;2.85), and frequent participation in domestic activities (PR=0.55 - 95%CI0.38;0.80). CONCLUSION: prevalence of negative self-rated health was high and was associated with sociodemographic, occupational, behavioral and health situation factors.

Literature Evidence and ARRIVE Assessment on Neuroprotective Effects of Flavonols in Neurodegenerative Diseases' Models.

BACKGROUND AND OBJECTIVE: This paper was based on a literature search of PubMed and Scielo databases using the keywords "Flavonoids, Neuroprotection, Quercetin, Rutin, Isoquercitrin, Alzheimer, Parkinson, Huntington" and combinations of all the words. METHOD: We collected relevant publications, during the period of 2000 to 2016, emphasizing in vivo and in vitro studies with neurological assessment of flavonol's potentials, as well as classifying studies according to evidence levels, in order to elucidate evidence-based literature and its application on clinical research. In addition, we highlight the importance of flavonols in modern research fields, indicating their neuroprotective potential and use thereof as preventive and therapeutic treatment of numerous neurodegenerative disease. Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and Huntington's disease, represent worldwide a major health problem with great financial impact. They are multifactorial diseases, hallmarked by similar pathogenesis that covers conditions such as oxidative stress, formation of free radicals, abnormal protein dynamics (degradation and aggregation), mitochondrial dysfunction, lipid peroxidation and cellular death or senescence. Flavonols are polyphenolic compounds, widely distributed in the plant kingdom and found in high concentrations in vegetables, fruits and teas. Their neuroprotective effects are mainly related to their antioxidant, anti-proliferative and anti-inflammatory properties. CONCLUSION: It was this paper's intention to contribute with an evidence analysis of recent studies approaching neuroprotective effects of flavonols and the potential to conduct human clinical studies.

Fatores associados a multimorbidades autorreferidas em trabalhadores da rede de saúde municipal / Factors associated with self-reported multimorbidities in workers from the municipal health network

Resumo Objetivo: estimar a prevalência de doenças crônicas não transmissíveis (DCNT) e investigar fatores associados a multimorbidades crônicas entre trabalhadores da rede de saúde municipal. Métodos: estudo transversal com profissionais da atenção básica à saúde de Diamantina, Minas Gerais, Brasil. Os dados foram coletados por entrevista com aplicação de instrumentos validados. Houve identificação das características individuais, hábitos e estilo de vida, estado de saúde e condições de trabalho da população estudada. Utilizou-se regressão logística para construção de modelos multivariáveis. Resultados: participaram da pesquisa 203 dos 257 trabalhadores elegíveis, 144 do sexo feminino e 59 do masculino. As morbidades mais prevalentes foram: sobrepeso (27,0%), hipertensão (17,2%) e depressão/estresse (16,2%). A presença de multimorbidades (28,6%) foi significativamente associada à idade superior a 48 anos (Odds ratio - OR: 4,28; intervalo de confiança de 95% - IC95%: 1,66;11,04), à presença de transtornos mentais comuns (OR: 3,23; IC95%: 1,50;6,96), enquanto o apoio social adequado no trabalho permaneceu como fator de proteção (OR: 0,25; IC95%: 0,11;0,57). Conclusão: a presença de multimorbidades foi associada a maior idade, presença de transtornos mentais comuns e características organizacionais do trabalho.

Abstract Objective: to estimate the prevalence of non-communicable chronic diseases (NCD) and investigate factors associated with chronic multimorbidities among workers from the municipal health network. Methods: cross-sectional study involving basic health care professionals from Diamantina, Minas Gerais, Brazil. The data were collected by an interview applying validated instruments. The studied population's individual characteristics, habits and lifestyle, health and work conditions were identified. Logistics regression was used to build the multivariate models. Results: 203 of the 257 eligible workers participated in this research, 144 women and 59 men. The most prevalent morbidities were: overweight (27.0%), hypertension (17.2%) and depression/stress (16.2%). The presence of multimorbidities (28.6%) was significantly associated to age over 48 years old (odds ratio - OR: 4,28; confidence interval of 95% - 95%CI: 1.66;11.04), to the presence of common mental disorders (OR: 3.23; 95%CI: 1.50;6.96), whereas the adequate social support at work remained as a protection factor (OR: 0.25; 95%CI: 0.11;0.57). Conclusion: the presence of multimorbidities was associated with older age, presence of common mental disorders, and work organizational characteristics.

Consumo de medicamentos para dormir entre trabalhadores da saúde do município de Diamantina, MG, e os fatores associados / Consumption of sleeping medication among health workers in the municipality of Diamantina/MG and associated factors

O objetivo do estudo foi identificar a prevalência do uso de medicamentos para dormir entre os trabalhadores da saúde da Secretaria Municipal de Saúde de Diamantina/MG e os fatores associados a esse consumo. Foi realizado um estudo transversal com 257 trabalhadores da saúde. A coleta de dados ocorreu entre dezembro de 2016 e março de 2017, por meio de entrevista estruturada. As associações entre as covariáveis e o uso de medicamentos para dormir foram analisadas por meio de regressão de Poisson com variância robusta. A prevalência do uso de medicamentos para dormir (15,3%) foi maior do que a descrita em outras populações, estando significativamente associada à idade mais avançada, maior escolaridade, contrato de trabalho, sono inadequado e relato de diagnóstico médico de depressão. Os resultados do estudo reforçam a importância de intervenções voltadas para a identificação precoce de fatores ambientais e organizacionais relacionados ao surgimento de sintomas mentais e de maior tomada de consciência sobre os efeitos deletérios do consumo inadequado de medicamentos controlados.

The study aimed to identify the prevalence of the use of sleeping medication among health workers of the Municipal Health Department of Diamantina/MG, and the factors associated with this consumption. A cross-sectional study was carried out with 257 health workers. The data collection took place between December 2016 and March 2017, through a structured interview. The associations between the covariates and the use of sleeping medication were analyzed using Poisson regression with robust variance. The prevalence of the use of sleeping medication (15.3%) was higher than that described in other populations, being significantly associated witholder age, higher schooling, work contract, inadequate sleep and reports of medical diagnosis of depression. The results of the study strengthen the importance of interventions aimed at the early identification of environmental and organizational factors related to the emergence of mental symptoms and greater awareness of the deleterious effects of the inappropriate consumption of controlled medicines.

Doping control analysis at the Rio 2016 Olympic and Paralympic Games.

This paper summarises the results obtained from the doping control analyses performed during the Summer XXXI Olympic Games (August 3-21, 2016) and the XV Paralympic Games (September 7-18, 2016). The analyses of all doping control samples were performed at the Brazilian Doping Control Laboratory (LBCD), a World Anti-Doping Agency (WADA)-accredited laboratory located in Rio de Janeiro, Brazil. A new facility at Rio de Janeiro Federal University (UFRJ) was built and fully operated by over 700 professionals, including Brazilian and international scientists, administrative staff, and volunteers. For the Olympic Games, 4913 samples were analysed. In 29 specimens, the presence of a prohibited substance was confirmed, resulting in adverse analytical findings (AAFs). For the Paralympic Games, 1687 samples were analysed, 12 of which were reported as AAFs. For both events, 82.8% of the samples were urine, and 17.2% were blood samples. In total, more than 31 000 analytical procedures were conducted. New WADA technical documents were fully implemented; consequently, state-of-the-art analytical toxicology instrumentation and strategies were applied during the Games, including different types of mass spectrometry (MS) analysers, peptide, and protein detection strategies, endogenous steroid profile measurements, and blood analysis. This enormous investment yielded one of the largest Olympic legacies in Brazil and South America. Copyright © 2017 John Wiley & Sons, Ltd.

Review of anticancer mechanisms of isoquercitin.

This review was based on a literature search of PubMed and Scielo databases using the keywords "quercetin, rutin, isoquercitrin, isoquercitin (IQ), quercetin-3-glucoside, bioavailability, flavonols and favonoids, and cancer" and combinations of all the words. We collected relevant scientific publications from 1990 to 2015 about the absorption, bioavailability, chemoprevention activity, and treatment effects as well as the underlying anticancer mechanisms of isoquercitin. Flavonoids are a group of polyphenolic compounds widely distributed throughout the plant kingdom. The subclass of flavonols receives special attention owing to their health benefits. The main components of this class are quercetin, rutin, and IQ, which is a flavonoid and although mostly found as a glycoside, is an aglycone (lacks a glycoside side chain). This compound presents similar therapeutic profiles to quercetin but with superior bioavailability, resulting in increased efficacy compared to the aglycone form. IQ has therapeutic applications owing to its wide range of pharmacological effects including antioxidant, antiproliferative, anti-inflammatory, anti-hypertensive, and anti-diabetic. The protective effects of IQ in cancer may be due to actions on lipid peroxidation. In addition, the antitumor effect of IQ and its underlying mechanism are related to interactions with Wnt signaling pathway, mixed-lineage protein kinase 3, mitogen-activated protein kinase, apoptotic pathways, as well proinflammatory protein signaling. This review contributed to clarifying the mechanisms of absorption, metabolism, and actions of IQ and isoquercitrin in cancer.

Parasitoses de interesse clínico em sedimento de rio: uma abordagem na Saúde Pública / Parasitoses of clinical interest in sediment of rio: an approach to Public Health

Falta de saneamento básico facilita a disseminação de doenças parasitárias que impactam à saúde humana, sendo o sedimento capaz de albergar esses microrganismos. Objetivo do presente estudo foi avaliar a presença de parasitas patogênicos ao ser humano em sedimentos de borda de rio, abordando os riscos de infecções parasitárias na questão de saúde pública. Avaliaram-se pela técnica de HPJ 80 amostras de sedimentos dos rios Paranhana e Caí. Obtiveram-se 53 amostras positivas (66,2%) com diferentes parasitas, Ancylostoma sp., Strongyloides sp., Endolimax nana, Ascaris lumbricoides, Toxocara canis, Giardia lamblia, Entamoeba coli, Entamoeba histolytica/dispar, Trichiuris trichiura e Taenia sp. Locais com maior urbanização apresentaram 60% de amostras positivas e maior número de espécies. O sedimento de borda de rio indicou ser um meio apropriado para a manutenção das formas infectantes de parasitas. Faz-se necessário um saneamento adequado, a fim de minimizar a contaminação ambiental bem como o risco à saúde da população.

Lack of basic sanitation facilitates the spread of parasitic diseases that impact human health, with the sediment being able to house these microorganisms. The present study aims to evaluate the presence of pathogenic parasites to humans in riverbank sediments, addressing the risks of parasitic infections in public health. Eighty samples of sediments from the Paranhana and Caí rivers were evaluated using the HPJ technique. Fifty-three positive samples (66.2%) were obtained with different parasites, Ancylostoma sp., Strongyloides sp., Endolimax nana, Ascaris lumbricoides, Toxocara canis, Giardia lamblia, Entamoeba coli, Entamoeba histolytica/dispar, Trichiuris trichiura and Taenia sp. Places with greater urbanization presented 60% of positive samples and a greater number of species. Riverbank sediments indicated to be an appropriate means for the maintenance of infectious forms of parasites. Adequate sanitation is necessary in order to minimize environmental contamination as well as the population's health risk.

Validation of a food frequency questionnaire for pregnant women attending primary care facilities / Validação de um questionário de frequência de consumo alimentar para gestantes atendidas em unidades básicas de saúde

INTRODUCTION: The Food Consumption Frequency Questionnaire (FCFQ) is a tool for assessing food consumption. However, to be used in pregnant women, it must be submitted to validation. The food consumption of pregnant women can impact on maternal and child health, becoming a public health issue. The questionnaire applied during pregnancy can create parameters for better prenatal careOBJECTIVE: To validate a FCFQ for pregnant women attended at primary health care unitsMETHODS: The Food Consumption Frequency Questionnaire and two 24-hour recall were applied to 155 pregnant women from the municipality of Montes Claros, Minas Gerais, Brazil. The questionnaire results were contrasted with the average of the two 24- hour recall using the chi-square test. The mean of the differences were estimated by limits of agreement. Pearson's correlation test and Intraclass Correlation Coefficient as well were used. Food consumption medians and quartiles were calculatedRESULTS: The value of estimate energy consumption and most nutrients was higher by the questionnaire. The concordance between the methods in the classification in quartiles of consumption was variable, being similar for 26.11% and opposite for 12.1%. After adjusting for energy, the correlation coefficient ranged from -0.144 (carbohydrate) to 0.337 (potassium). The questionnaire estimated values were approximately 1.94 higher than the 24 hour recall, corresponding to 20% higher for almost all nutrientsCONCLUSION: The FCFQ showed to be a good instrument to be considered clinically as well as for research purposes in Brazilian pregnant women, this tool measures appropriately food intake which is fundamental for establishing health conditions during pregnancy, helping to assess the association between diet, nutrition and health

INTRODUÇÃO: O Questionário de Frequência de Consumo Alimentar (QFCA) é uma ferramenta para avaliação do consumo alimentar. No entanto, para ser empregado em gestantes, deve ser submetido a validação. O consumo alimentar de gestantes pode impactar na saúde materno-infantil, se tornando uma questão de saúde pública. O QFCA aplicado na gestação pode criar parâmetros para melhor assistência pré-natalOBJETIVO: Validar um Questionário de Frequência de Consumo Alimentar para gestantes atendidas em unidades básicas de saúdeMÉTODO: O QFCA e dois recordatório 24 horas (R24h) foram aplicados a 155 gestantes de Montes Claros, MG. Foram contrastados os resultados do QFCA com a média dos dois R24h usando o teste de qui-quadrado. A média das diferenças foram estimadas pelos métodos por limites de concordância. Utilizou-se o teste de Correlação de Pearson e Coeficiente de Correlação Intraclasse (CCI). Foram calculados medianas e quartis do consumo alimentarRESULTADOS: A estimativa do consumo de energia e da maioria dos nutrientes foi maior pelo QFCA. A concordância entre os métodos na classificação em quartis de consumo foi variável, sendo semelhante para 26,11% e oposta em 12,1%. Após o ajuste de energia, o coeficiente de correlação variou de -0,144 (carboidrato) a 0,337 (potássio). As estimativas do QFCA foram aproximadamente 1,94 maiores que as do R24h, correspondendo a valores 20% superiores para quase todos os nutrientesCONCLUSÃO: O estudo mostrou evidências de validação do QFCA, sugerindo que é instrumento potencial para ser usado na avaliação do consumo alimentar em gestantes

Prevalência e fatores associados à autoavaliação negativa de saúde entre trabalhadores da rede municipal de saúde de Diamantina, Minas Gerais / Prevalencia y factores asociados a la autoevaluación negativa de salud entre trabajadores de la red municipal de salud de Diamantina, Minas Gerais, Brasil / Prevalence of negative self-rated health and associated factors among healthcare workers in a Southeast Brazilian city

Resumo Objetivo investigar a prevalência e os fatores associados à autoavaliação negativa de saúde entre trabalhadores da rede municipal de saúde de Diamantina, MG, Brasil. Métodos estudo transversal censitário, com emprego da regressão de Poisson. Resultados participaram 203 trabalhadores, 70,9% do sexo feminino e 57,1% com até 38 anos de idade; a prevalência de autoavaliação negativa de saúde foi de 28,6% (IC 95% 22,4%;34,8%); na análise múltipla, associaram-se ao desfecho a idade ≥39 anos (RP=1,56 - IC 95% 1,01;2,40), renda familiar mensal >3 salários mínimos (RP=0,63 - IC 95% 0,41;0,97), exercer outra atividade remunerada (RP=0,55 - IC 95% 0,34;0,89), baixa qualidade do sono (RP=1,99 - IC 95% 1,32;2,99), diagnóstico de morbidade (RP=2,33 - IC 95% 1,13;4,81) ou multimorbidades (RP=2,63 - IC 95% 1,32;5,24), ter sofrido agressão no trabalho (RP=1,92 - IC 95% 1,29;2,85) e participação frequente nas atividades domésticas (RP=0,55 - IC 95% 0,38;0,80). Conclusão a autoavaliação negativa da saúde teve prevalência elevada e associou-se a fatores sociodemográficos, ocupacionais, comportamentais e de situação de saúde.

Resumen Objetivo investigar la prevalencia de autoevaluación negativa de salud y factores asociados entre trabajadores del sistema municipal de salud de Diamantina, MG. Métodos estudio transversal censal por medio de la regresión de Poisson. Resultados entre 203 participantes, el 70,9% era de mujeres y el 57,1% tenía hasta 38 años de edad; la prevalencia de autoevaluación negativa de salud fue del 28,6% (IC 95% 22,4;34,8); a partir del análisis múltiple, se asoció el resultado a la edad de 39 años o superior (RP=1,56 - IC 95% 1,01;2,40), renta familiar mensual >3 salários mínimos (RP=0,63 - IC 95% 0,41;0,97), ejercer otras actividades remuneradas (RP=0,55 - IC 95% 0,34;0,89), mala calidad de sueño (RP=1,99 - IC 95% 1,32;2,99), diagnósticos de morbilidad (RP=2,33 - IC 95% 1,13;4,81) o multimorbilidades (RP=2,63 - IC 95% 1,32;5,24), agresión sufrida en el trabajo (RP=1,92 - IC 95% 1,29;2,85) y actividades domésticas frecuentes (RP=0,55 - IC 95% 0,38;0,80). Conclusión la prevalencia de la autoevaluación negativa de salud fue elevada y fue asociada a factores sociodemográficos, ocupacionales, conductuales y de salud.

Abstract Objective to investigate the prevalence of negative self-rated health and associated factors among municipal health service workers in Diamantina, MG, Brazil. Methods this was a cross-sectional census study using Poisson regression. Results 203 health workers took part in the study, 70.9% were female, and 57.1% were up to 38 years old; prevalence of negative self-rated health was 28.6% (95%CI22.4;34.8); in the multivariate analysis, the following were associated with the outcome: being 39 years old or more (PR=1.56 - 95%CI1.01;2.40), monthly family income >3 minimum wages (PR=0.63 - 95%CI0.41;0.97), having another paid occupation (PR=0.55 - 95%CI0.34;0.89), poor sleep quality (PR=1.99 - 95%CI1.32;2.99), diagnosis of one disease (PR=2.33 - 95%CI1.13;4.81) or multiple diseases (PR=2.63 - 95%CI1.32;5.24), suffering aggression at work (PR=1.92 - 95%CI1.29;2.85), and frequent participation in domestic activities (PR=0.55 - 95%CI0.38;0.80). Conclusion prevalence of negative self-rated health was high and was associated with sociodemographic, occupational, behavioral and health situation factors.

Violência no trabalho entre trabalhadores municipais do setor saúde de Diamantina, MG, 2017 / Workplace violence among municipal health care workers in Diamantina, Minas Gerais, Brazil, 2017

Introdução: Trabalhadores do setor saúde são destaques em estudos recentes pelas proporções significativas de vivência de violência no trabalho. Objetivo: Estimar a prevalência e os fatores associados à violência entre trabalhadores da saúde. Método: Estudo de corte transversal, realizado com trabalhadores municipais de saúde. A coleta de dados ocorreu de dezembro de 2016 a março de 2017, por meio de entrevistas a trabalhadores da saúde de Diamantina (MG). Para a análise, a variável violência no trabalho foi tratada como desfecho em análises bivariada e múltiplas. Foram utilizadas técnicas de estatística descritivas e analíticas (regressão de Poisson). Resultados: Participaram da pesquisa 203 trabalhadores municipais de saúde (taxa de resposta de 79%). A prevalência de violência no trabalho foi de 40,4% no total, sendo de 47,9% entre as mulheres e de 22,0% entre os homens. Os fatores do trabalho associados à violência foram a satisfação com o trabalho, o baixo apoio e a alta demanda psicológica no trabalho. Conclusão: A prevalência evidenciada e as associações sugeridas direcionam para a necessidade de reformular e criar políticas de proteção à saúde dos trabalhadores da saúde de modo que amenize os possíveis efeitos dessa experiência na saúde do trabalhador e na qualidade do serviço prestado

Background: Health care workers stand out in recent studies as a function of high rates of workplace violence. Objective: To calculate the prevalence of workplace violence involving health care workers and associated factors. Methods: Cross-sectional study with municipal health care workers in Diamantina, Minas Gerais, Brazil. Data were collected in interviews from December 2016 through March 2017. Variable workplace violence was considered as outcome on univariate and multivariate analysis. Descriptive and analytical statistical techniques were used (Poisson regression). Results: The study population comprised 203 municipal health care workers (79% response rate). The prevalence of workplace violence was 40.4­47.9% for women and 22.0% for men. Occupational factors associated with violence were job satisfaction, support at work and psychological demands. Conclusion: The prevalence rates we found and associated factors point to the relevance of health protection policies targeting this category of workers which may contribute to mitigate the negative effects of violence on the health of workers and consequently on the quality of care delivery

Lanthanum content and effects on growth, gas exchanges, and chlorophyll index in maize plants / Teor de lantânio e efeitos no crescimento, trocas gasosas e teor de clorofila em plantas de milho

Rare earth elements, such as lanthanum (La), have been applied to agriculture via fertilizers, aiming to increase the productivity and crop quality, such results observed mainly in China. However, the knowledge about the effect of La on maize growth, as well as for other species, despite the growing interest it is still limited. The aim of this study was to evaluate the effects of La on maize growth, La content,photosynthetic rate and chlorophyll content in maize plants in response to La treatment (0, 25, 50, 100, 150, 300 and 600 μM) in nutrient solution for three weeks. The plants were placed in geminated pots using a split-root technique. One of the pots in the geminated set was filled with a complete nutrient solution without La, while another was filled with a nutrient solution without phosphorus but containing different concentrations of La. It was verified that roots of maize plants can accumulate approximately sixty percent more La than shoots. Moreover, low La concentrations stimulated an increase in chlorophyll index,resulting in a slight increase in shoot biomass. At higher levels, La didn’t reduce growth but caused adecrease in both photosynthetic rate and chlorophyll index.

Elementos terra rara, como lantânio (La), são aplicados à agricultura via fertilizantes, com oobjetivo de aumentar a produtividade e a qualidade das culturas agrícolas, fato observado principalmente naChina. Entretanto, o conhecimento sobre o efeito de La no crescimento do milho, bem como para outrasculturas agrícolas, ainda é limitado apesar do interesse crescente. O presente estudo objetivou avaliar oefeito da aplicação de La sobre o crescimento, teor de La, fotossíntese e teor de clorofila em plantas demilho, expostas a concentrações crescentes de La (0, 25, 50, 100, 150, 300 e 600 μM) em solução nutritivapor três semanas. As plantas foram colocadas em vasos geminados usando uma técnica de raiz divisória.Um dos potes no conjunto geminado foi preenchido com solução nutritiva completa que não continha La,enquanto outra foi preenchida com solução nutritiva sem fósforo, mas contendo diferentes concentraçõesde La. Foi verificado que as raízes das plantas de milho podem acumular sessenta por cento mais La quandocomparado à parte aérea. Além disso, as baixas concentrações de La estimularam o aumento do teor declorofila, resultando em um aumento na biomassa da parte aérea. Em concentrações mais elevadas, aaplicação de La não reduziu o crescimento das plantas de milho, mas causou diminuição na taxafotossintética e no índice de clorofila.

Fatores de risco para absenteísmo de curta duração em um hospital de médio porte / Risk factors for short-term absenteeism in medium-sized hospital

Resumo Introdução Existem evidências sobre absenteísmo-doença no contexto hospitalar, mas são necessários estudos não só com profissionais do setor de assistência, mas também com outros de diferentes setores. Objetivos Investigar a associação entre a prevalência de absenteísmo-doença e as características individuais, os hábitos e o estilo de vida, o estado de saúde e as condições de trabalho entre trabalhadores de um hospital filantrópico de médio porte. Método Estudo transversal com amostra probabilística de 123 profissionais dos setores de assistência, de apoio e administrativo. Foram obtidas informações autodeclaradas sobre ausência do trabalho, características sociodemográficas, estilo de vida, estado de saúde e condições de trabalho. Razões de prevalência de absenteísmo e seus respectivos intervalos de confiança de 95% foram ajustados pela técnica de regressão multivariada de Poisson. Resultados A prevalência de absenteísmo nos últimos 12 meses foi de 28,5%, independentemente do setor de trabalho. A presença de doença ocupacional, a alta demanda física e psicológica e o tempo de trabalho no hospital permaneceram associados ao absenteísmo após o ajuste multivariado dos dados. Conclusão Condições precárias de trabalho estão associadas ao absenteísmo-doença entre os profissionais investigados. Esse achado deve ser levado em consideração na formulação de intervenções que envolvem a promoção da saúde desses trabalhadores.

Abstract Introduction Even though there are evidences of absenteeism in the hospital context, more studies are needed beyond the care sector. Objectives to investigate the associations between the prevalence of absenteeism of three sectors employees of a philanthropic medium-sized hospital and individual characteristics, life habits, health status and working conditions. Method Cross-sectional study with random sample of 123 professionals from care, administrative and support sectors. The data was collected through a self-administered questionnaire that included information on absence from work, socio-demographic, habits and lifestyle characteristics, health status and working conditions. Prevalence ratios of absenteeism and their respective 95% confidence intervals were adjusted by Poisson multivariate regression. Results The prevalence of absenteeism due to sickness in last 12 months was 28.5% and it was associated with high physical and psychological demands, working time at the hospital and presence of occupational diseases. Conclusion Precarious working conditions are associated sickness absenteeism among professionals investigated. This finding must be considered in the formulation of interventions involving the health promotion of these workers.

Deslocamento de Artibeus lituratus (Olfers, 1818) (Mammalia, Chiroptera) entre ilha e continente no Estado do Rio de Janeiro, Brasil / Movement of Artibeus lituratus (Olfers, 1818) (Mammalia, Chiroptera) between island and continent on State of Rio de Janeiro, Brazil

Em 18 de julho de 2007, um indivíduo de Artibeus lituratus marcado com coleira plástica numerada foi recapturado no Parque Natural Municipal da Serra do Mendanha, município do Rio de Janeiro, 96 dias após ter sido capturado e marcado na Ilha de Itacuruça, no sul do Estado do Rio de Janeiro. A distância linear entre os pontos de marcação e recaptura sugere um deslocamento de no mínimo 35 km, sendo 500 m sobre o mar.

One individual of Artibeus lituratus, marked with a colored and numbered plastic color necklace was recaptured on July 18th, 2007 at the Parque Natural Municipal da Serra do Mendanha, Rio de Janeiro, Brazil, 96 days after being captured and marked at Itacuruça Island, located on southern Rio de Janeiro State. The linear distance between the plots of marking and recapture suggests a minimum movement of 35 km, being 500 m oversea.