Pesquisa | BVS Violência e Saúde

1.

Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis.

Alhaj Hussen, Kutaiba; Vu Manh, Thien-Phong; Guimiot, Fabien; Nelson, Elisabeth; Chabaane, Emna; Delord, Marc; Barbier, Maxime; Berthault, Claire; Dulphy, Nicolas; Alberdi, Antonio José; Burlen-Defranoux, Odile; Socié, Gerard; Bories, Jean Christophe; Larghero, Jerôme; Vanneaux, Valérie; Verhoeyen, Els; Wirth, Thierry; Dalod, Marc; Gluckman, Jean Claude; Cumano, Ana; Canque, Bruno.

Immunity ; 47(4): 680-696.e8, 2017 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-29045900

2.

High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome.

Chretien, Anne-Sophie; Devillier, Raynier; Granjeaud, Samuel; Cordier, Charlotte; Demerle, Clemence; Salem, Nassim; Wlosik, Julia; Orlanducci, Florence; Gorvel, Laurent; Fattori, Stephane; Hospital, Marie-Anne; Pakradouni, Jihane; Gregori, Emilie; Paul, Magali; Rochigneux, Philippe; Pagliardini, Thomas; Morey, Mathieu; Fauriat, Cyril; Dulphy, Nicolas; Toubert, Antoine; Luche, Herve; Malissen, Marie; Blaise, Didier; Nunès, Jacques A; Vey, Norbert; Olive, Daniel.

Proc Natl Acad Sci U S A ; 118(22)2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-34050021

3.

Hematologic disorder-associated Cxcr4 gain-of-function mutation leads to uncontrolled extrafollicular immune response.

Alouche, Nagham; Bonaud, Amélie; Rondeau, Vincent; Hussein-Agha, Rim; Nguyen, Julie; Bisio, Valeria; Khamyath, Mélanie; Crickx, Etienne; Setterblad, Niclas; Dulphy, Nicolas; Mahevas, Matthieu; McDermott, David H; Murphy, Philip M; Balabanian, Karl; Espéli, Marion.

Blood ; 137(22): 3050-3063, 2021 06 03.

Artigo em Inglês | MEDLINE | ID: mdl-33512437

4.

The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).

Berthelet, Jérémy; Michail, Christina; Bui, Linh-Chi; Le Coadou, Louise; Sirri, Valentina; Wang, Li; Dulphy, Nicolas; Dupret, Jean-Marie; Chomienne, Christine; Guidez, Fabien; Rodrigues-Lima, Fernando.

Mol Pharmacol ; 100(3): 283-294, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34266924

5.

Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study.

Rea, Delphine; Henry, Guylaine; Khaznadar, Zena; Etienne, Gabriel; Guilhot, François; Nicolini, Franck; Guilhot, Joelle; Rousselot, Philippe; Huguet, Françoise; Legros, Laurence; Gardembas, Martine; Dubruille, Viviane; Guerci-Bresler, Agnès; Charbonnier, Aude; Maloisel, Frédéric; Ianotto, Jean-Christophe; Villemagne, Bruno; Mahon, François-Xavier; Moins-Teisserenc, Hélène; Dulphy, Nicolas; Toubert, Antoine.

Haematologica ; 102(8): 1368-1377, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28522576

6.

Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion.

Khaznadar, Zena; Boissel, Nicolas; Agaugué, Sophie; Henry, Guylaine; Cheok, Meyling; Vignon, Marguerite; Geromin, Daniela; Cayuela, Jean-Michel; Castaigne, Sylvie; Pautas, Cécile; Raffoux, Emmanuel; Lachuer, Joel; Sigaux, François; Preudhomme, Claude; Dombret, Hervé; Dulphy, Nicolas; Toubert, Antoine.

J Immunol ; 195(6): 2580-90, 2015 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-26246143

7.

Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse.

Khaznadar, Zena; Henry, Guylaine; Setterblad, Niclas; Agaugue, Sophie; Raffoux, Emmanuel; Boissel, Nicolas; Dombret, Hervé; Toubert, Antoine; Dulphy, Nicolas.

Eur J Immunol ; 44(10): 3068-80, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25041786

8.

AHR: leukemic countermeasure against NK cells.

Dulphy, Nicolas.

Blood ; 132(17): 1733-1734, 2018 10 25.

Artigo em Inglês | MEDLINE | ID: mdl-30361461

9.

At diagnosis, diffuse large B-cell lymphoma patients show impaired rituximab-mediated NK-cell cytotoxicity.

Danielou-Lazareth, Anne; Henry, Guylaine; Geromin, Daniela; Khaznadar, Zena; Briere, Josette; Tamouza, Ryad; Cayuela, Jean-Michel; Thieblemont, Catherine; Toubert, Antoine; Dulphy, Nicolas.

Eur J Immunol ; 43(5): 1383-8, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23400905

10.

Favorable impact of natural killer cell reconstitution on chronic graft-versus-host disease and cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation.

Kheav, Vissal David; Busson, Marc; Scieux, Catherine; Peffault de Latour, Régis; Maki, Guitta; Haas, Philippe; Mazeron, Marie-Christine; Carmagnat, Maryvonnick; Masson, Emeline; Xhaard, Aliénor; Robin, Marie; Ribaud, Patricia; Dulphy, Nicolas; Loiseau, Pascale; Charron, Dominique; Socié, Gérard; Toubert, Antoine; Moins-Teisserenc, Hélène.

Haematologica ; 99(12): 1860-7, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25085354

11.

Immune-monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium.

Tentori, Cristina A; Zhao, Lin P; Tinterri, Benedetta; Strange, Kathryn E; Zoldan, Katharina; Dimopoulos, Konstantinos; Feng, Xingmin; Riva, Elena; Lim, Benjamin; Simoni, Yannick; Murthy, Vidhya; Hayes, Madeline J; Poloni, Antonella; Padron, Eric; Cardoso, Bruno A; Cross, Michael; Winter, Susann; Santaolalla, Aida; Patel, Bhavisha A; Groarke, Emma M; Wiseman, Daniel H; Jones, Katy; Jamieson, Lauren; Manogaran, Charles; Daver, Naval; Gallur, Laura; Ingram, Wendy; Ferrell, P Brent; Sockel, Katja; Dulphy, Nicolas; Chapuis, Nicolas; Kubasch, Anne S; Olsnes, Astrid M; Kulasekararaj, Austin; De Lavellade, Hugues; Kern, Wolfgang; Van Hemelrijck, Mieke; Bonnet, Dominique; Westers, Theresia M; Freeman, Sylvie; Oelschlaegel, Uta; Valcarcel, David; Raddi, Marco G; Grønbæk, Kirsten; Fontenay, Michaela; Loghavi, Sanam; Santini, Valeria; Almeida, Antonio M; Irish, Jonathan M; Sallman, David A.

Hemasphere ; 8(5): e64, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38756352

12.

NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation.

Haas, Philippe; Loiseau, Pascale; Tamouza, Ryad; Cayuela, Jean-Michel; Moins-Teisserenc, Hélène; Busson, Marc; Henry, Guylaine; Falk, Christine S; Charron, Dominique; Socié, Gérard; Toubert, Antoine; Dulphy, Nicolas.

Blood ; 117(3): 1021-9, 2011 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-21045194

13.

Modulation of NK cell activation by exogenous calcium from alginate dressings in vitro.

Adib, Yara; Boy, Maxime; Serror, Kevin; Dulphy, Nicolas; des Courtils, Céline; Duciel, Laura; Boccara, David; Mimoun, Maurice; Samardzic, Marina; Bagot, Martine; Bensussan, Armand; Michel, Laurence.

Front Immunol ; 14: 1141047, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37090742

14.

Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation.

Boy, Maxime; Bisio, Valeria; Zhao, Lin-Pierre; Guidez, Fabien; Schell, Bérénice; Lereclus, Emilie; Henry, Guylaine; Villemonteix, Juliette; Rodrigues-Lima, Fernando; Gagne, Katia; Retiere, Christelle; Larcher, Lise; Kim, Rathana; Clappier, Emmanuelle; Sebert, Marie; Mekinian, Arsène; Fain, Olivier; Caignard, Anne; Espeli, Marion; Balabanian, Karl; Toubert, Antoine; Fenaux, Pierre; Ades, Lionel; Dulphy, Nicolas.

Nat Commun ; 14(1): 588, 2023 02 03.

Artigo em Inglês | MEDLINE | ID: mdl-36737440

15.

WHIM Syndrome-linked CXCR4 mutations drive osteoporosis.

Anginot, Adrienne; Nguyen, Julie; Abou Nader, Zeina; Rondeau, Vincent; Bonaud, Amélie; Kalogeraki, Maria; Boutin, Antoine; Lemos, Julia P; Bisio, Valeria; Koenen, Joyce; Hanna Doumit Sakr, Lea; Picart, Amandine; Coudert, Amélie; Provot, Sylvain; Dulphy, Nicolas; Aurrand-Lions, Michel; Mancini, Stéphane J C; Lazennec, Gwendal; McDermott, David H; Guidez, Fabien; Blin-Wakkach, Claudine; Murphy, Philip M; Cohen-Solal, Martine; Espéli, Marion; Rouleau, Matthieu; Balabanian, Karl.

Nat Commun ; 14(1): 2058, 2023 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-37045841

16.

Reduced peripheral blood dendritic cell and monocyte subsets in MDS patients with systemic inflammatory or dysimmune diseases.

Jachiet, Vincent; Ricard, Laure; Hirsch, Pierre; Malard, Florent; Pascal, Laurent; Beyne-Rauzy, Odile; Peterlin, Pierre; Maria, Alexandre Thibault Jacques; Vey, Norbert; D'Aveni, Maud; Gourin, Marie-Pierre; Dimicoli-Salazar, Sophie; Banos, Anne; Wickenhauser, Stefan; Terriou, Louis; De Renzis, Benoit; Durot, Eric; Natarajan-Ame, Shanti; Vekhoff, Anne; Voillat, Laurent; Park, Sophie; Vinit, Julien; Dieval, Céline; Dellal, Azeddine; Grobost, Vincent; Willems, Lise; Rossignol, Julien; Solary, Eric; Kosmider, Olivier; Dulphy, Nicolas; Zhao, Lin Pierre; Adès, Lionel; Fenaux, Pierre; Fain, Olivier; Mohty, Mohamad; Gaugler, Béatrice; Mekinian, Arsène.

Clin Exp Med ; 23(3): 803-813, 2023 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-35953763

17.

Activation of the receptor NKG2D leads to production of Th17 cytokines in CD4+ T cells of patients with Crohn's disease.

Pariente, Benjamin; Mocan, Iulia; Camus, Matthieu; Dutertre, Charles-Antoine; Ettersperger, Julien; Cattan, Pierre; Gornet, Jean-Marc; Dulphy, Nicolas; Charron, Dominique; Lémann, Marc; Toubert, Antoine; Allez, Matthieu.

Gastroenterology ; 141(1): 217-26, 226.e1-2, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21600899

18.

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants.

Roux, Anne-Laure; Ray, Aurélie; Pawlik, Alexandre; Medjahed, Halima; Etienne, Gilles; Rottman, Martin; Catherinot, Emilie; Coppée, Jean-Yves; Chaoui, Karima; Monsarrat, Bernard; Toubert, Antoine; Daffé, Mamadou; Puzo, Germain; Gaillard, Jean-Louis; Brosch, Roland; Dulphy, Nicolas; Nigou, Jérôme; Herrmann, Jean-Louis.

Cell Microbiol ; 13(5): 692-704, 2011 May.

Artigo em Inglês | MEDLINE | ID: mdl-21143571

19.

Innate lymphoid cells: NK and cytotoxic ILC3 subsets infiltrate metastatic breast cancer lymph nodes.

Rethacker, Louise; Boy, Maxime; Bisio, Valeria; Roussin, France; Denizeau, Jordan; Vincent-Salomon, Anne; Borcoman, Edith; Sedlik, Christine; Piaggio, Eliane; Toubert, Antoine; Dulphy, Nicolas; Caignard, Anne.

Oncoimmunology ; 11(1): 2057396, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35371620

20.

MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease.

Boukouaci, Wahid; Busson, Marc; Peffault de Latour, Régis; Rocha, Vanderson; Suberbielle, Caroline; Bengoufa, Djaouida; Dulphy, Nicolas; Haas, Philippe; Scieux, Catherine; Amroun, Habiba; Gluckman, Eliane; Krishnamoorthy, Rajagopal; Toubert, Antoine; Charron, Dominique; Socié, Gérard; Tamouza, Ryad.

Blood ; 114(25): 5216-24, 2009 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-19786616

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