Detalhe da pesquisa
1.
ALS iPSC-derived microglia and motor neurons respond to astrocyte-targeted IL-10 and CCL2 modulation.
Hum Mol Genet
; 33(6): 530-542, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38129120
2.
Sickle cell disease iPSC-derived sensory neurons exhibit increased excitability and sensitization to patient plasma.
Blood
; 143(20): 2037-2052, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427938
3.
SRCP1 Conveys Resistance to Polyglutamine Aggregation.
Mol Cell
; 71(2): 216-228.e7, 2018 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30029002
4.
Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy.
Proc Natl Acad Sci U S A
; 120(47): e2300308120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37976261
5.
Assessment of cerebral spinal fluid biomarkers and microRNA-mediated disease mechanisms in spinal muscular atrophy patient samples.
Hum Mol Genet
; 31(11): 1830-1843, 2022 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919695
6.
Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus.
J Virol
; 97(10): e0069623, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37796129
7.
Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS.
Gene Ther
; 30(6): 528-533, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34239068
8.
Diminished motor neuron activity driven by abnormal astrocytic EAAT1 glutamate transporter activity in spinal muscular atrophy is not fully restored after lentiviral SMN delivery.
Glia
; 71(5): 1311-1332, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36655314
9.
Nitric Oxide Attenuates Human Cytomegalovirus Infection yet Disrupts Neural Cell Differentiation and Tissue Organization.
J Virol
; 96(14): e0012622, 2022 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35862705
10.
Viral mediated knockdown of GATA6 in SMA iPSC-derived astrocytes prevents motor neuron loss and microglial activation.
Glia
; 70(5): 989-1004, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35088910
11.
AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/-SMA model mice.
Hum Mol Genet
; 28(19): 3199-3210, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31211843
12.
Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and Organoids.
J Virol
; 93(17)2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217241
13.
Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.
Hum Mol Genet
; 26(17): 3409-3420, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637335
14.
SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons.
Hum Mol Genet
; 25(3): 514-23, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26643950
15.
Astrocytes influence the severity of spinal muscular atrophy.
Hum Mol Genet
; 24(14): 4094-102, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25911676
16.
Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy.
Mol Ther
; 24(9): 1592-601, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401142
17.
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
Am J Hum Genet
; 93(6): 1001-14, 2013 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24239381
18.
Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results.
Mol Pain
; 11: 5, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25888914
19.
COPI transport complexes bind to specific RNAs in neuronal cells.
Hum Mol Genet
; 22(4): 729-36, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23175440
20.
Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease.
Biochem Soc Trans
; 43(3): 390-5, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26009181