Detalhe da pesquisa
1.
ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.
Mol Cell
; 82(13): 2443-2457.e7, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35613620
2.
Japanese Society of Medical Oncology clinical guidelines: Molecular testing for colorectal cancer treatment, 5th edition.
Cancer Sci
; 115(3): 1014-1021, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38263580
3.
Effects of ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of abemaciclib.
Eur J Clin Pharmacol
; 78(8): 1239-1247, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35527301
4.
CIRCULATE-Japan: Circulating tumor DNA-guided adaptive platform trials to refine adjuvant therapy for colorectal cancer.
Cancer Sci
; 112(7): 2915-2920, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33931919
5.
FMS-like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer.
Cancer Sci
; 112(1): 314-322, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33075166
6.
Serum concentration of the CKD4/6 inhibitor abemaciclib, but not of creatinine, strongly predicts hematological adverse events in patients with breast cancer: a preliminary report.
Invest New Drugs
; 39(1): 272-277, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856274
7.
The ADAM17 protease promotes tobacco smoke carcinogen-induced lung tumorigenesis.
Carcinogenesis
; 41(4): 527-538, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31257400
8.
Japanese Society of Medical Oncology Clinical Guidelines: Molecular Testing for Colorectal Cancer Treatment, 4th edition.
Cancer Sci
; 111(10): 3962-3969, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667108
9.
Anaplastic lymphoma kinase expression in small-cell lung cancer.
Histopathology
; 75(1): 20-28, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30790327
10.
Japanese Society of Medical Oncology Clinical Guidelines: Molecular Testing for Colorectal Cancer Treatment, Third Edition.
Cancer Sci
; 109(6): 2074-2079, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29873882
11.
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Nature
; 483(7391): 613-7, 2012 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22425996
12.
Pulmonary carcinosarcoma showing an obvious response to pazopanib: a case report.
BMC Pulm Med
; 18(1): 193, 2018 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30541518
13.
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.
Proc Natl Acad Sci U S A
; 112(11): E1288-96, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737542
14.
[Successful Long-Term Treatment with Intermittent Oxaliplatin Administration for Recurrent Sigmoid Colon Cancer without Developing Neuropathy].
Gan To Kagaku Ryoho
; 45(7): 1113-1116, 2018 Jul.
Artigo
em Japonês
| MEDLINE | ID: mdl-30042284
15.
Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.
Carcinogenesis
; 38(11): 1063-1072, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28968756
16.
PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1.
Proc Natl Acad Sci U S A
; 110(52): 21124-9, 2013 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24327733
17.
Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients.
Cancer Sci
; 106(3): 324-7, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25800101
18.
Not just gRASping at flaws: finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers.
Cancer Sci
; 105(5): 499-505, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24612015
19.
Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK.
Proc Natl Acad Sci U S A
; 108(18): 7535-40, 2011 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21502504
20.
Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS.
Nat Cancer
; 4(6): 829-843, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277529