Pesquisa | BVS Violência e Saúde

1.

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.

Zhang, Lei; Li, Ziyi; Skrzypczynska, Katarzyna M; Fang, Qiao; Zhang, Wei; O'Brien, Sarah A; He, Yao; Wang, Lynn; Zhang, Qiming; Kim, Aeryon; Gao, Ranran; Orf, Jessica; Wang, Tao; Sawant, Deepali; Kang, Jiajinlong; Bhatt, Dev; Lu, Daniel; Li, Chi-Ming; Rapaport, Aaron S; Perez, Kristy; Ye, Yingjiang; Wang, Shan; Hu, Xueda; Ren, Xianwen; Ouyang, Wenjun; Shen, Zhanlong; Egen, Jackson G; Zhang, Zemin; Yu, Xin.

Cell ; 181(2): 442-459.e29, 2020 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-32302573

2.

Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials.

Egen, Jackson G; Ouyang, Wenjun; Wu, Lawren C.

Immunity ; 52(1): 36-54, 2020 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-31940272

3.

C3/CD11b-Mediated Leishmania major Internalization by Neutrophils Induces Intraphagosomal NOX2-Mediated Respiratory Burst but Fails to Eliminate Parasites and Induces a State of Stalled Apoptosis.

Ranson, Adam J; Carneiro, Matheus B; Perks, Benjamin; Penner, Robert; Melo, Leon; Canton, Johnathan; Egen, Jackson; Peters, Nathan C.

J Immunol ; 211(1): 103-117, 2023 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-37195185

4.

IgEâº memory B cells and plasma cells generated through a germinal-center pathway.

Talay, Oezcan; Yan, Donghong; Brightbill, Hans D; Straney, Elizabeth E M; Zhou, Meijuan; Ladi, Ena; Lee, Wyne P; Egen, Jackson G; Austin, Cary D; Xu, Min; Wu, Lawren C.

Nat Immunol ; 13(4): 396-404, 2012 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-22366892

5.

Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity.

Kim, Jennie C; Liu, Xian; Fitzgerald, Karen; Eng, Jason S; Orf, Jessica; O'Brien, Sarah A; Belmontes, Brian; Casbon, Amy-Jo; Novitskiy, Sergey V; Tarbell, Kristin V; DeVoss, Jason; Egen, Jackson G.

Cancer Immunol Immunother ; 72(5): 1327-1335, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-36394642

6.

Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues.

Honda, Tetsuya; Egen, Jackson G; Lämmermann, Tim; Kastenmüller, Wolfgang; Torabi-Parizi, Parizad; Germain, Ronald N.

Immunity ; 40(2): 235-247, 2014 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-24440150

7.

Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node.

Kastenmüller, Wolfgang; Brandes, Marlene; Wang, Ze; Herz, Jasmin; Egen, Jackson G; Germain, Ronald N.

Immunity ; 38(3): 502-13, 2013 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-23352234

8.

Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment.

O'Brien, Sarah A; Orf, Jessica; Skrzypczynska, Katarzyna M; Tan, Hong; Kim, Jennie; DeVoss, Jason; Belmontes, Brian; Egen, Jackson G.

Cancer Immunol Immunother ; 70(8): 2401-2410, 2021 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-33511454

9.

LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8⁺ T Cells.

Kim, Aeryon; Han, Chia-Jung; Driver, Ian; Olow, Aleksandra; Sewell, Andrew K; Zhang, Zemin; Ouyang, Wenjun; Egen, Jackson G; Yu, Xin.

J Immunol ; 203(4): 1076-1087, 2019 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-31253728

10.

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.

Lafkas, Daniel; Shelton, Amy; Chiu, Cecilia; de Leon Boenig, Gladys; Chen, Yongmei; Stawicki, Scott S; Siltanen, Christian; Reichelt, Mike; Zhou, Meijuan; Wu, Xiumin; Eastham-Anderson, Jeffrey; Moore, Heather; Roose-Girma, Meron; Chinn, Yvonne; Hang, Julie Q; Warming, Søren; Egen, Jackson; Lee, Wyne P; Austin, Cary; Wu, Yan; Payandeh, Jian; Lowe, John B; Siebel, Christian W.

Nature ; 528(7580): 127-31, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26580007

11.

Addendum: IgE+ memory B cells and plasma cells generated through a germinal-center pathway.

Talay, Oezcan; Yan, Donghong; Brightbill, Hans D; Straney, Elizabeth E M; Zhou, Meijuan; Ladi, Ena; Lee, Wyne P; Egen, Jackson G; Austin, Cary D; Xu, Min; Wu, Lawren C.

Nat Immunol ; 14(12): 1302-4, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24240161

12.

Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.

Egen, Jackson G; Rothfuchs, Antonio Gigliotti; Feng, Carl G; Horwitz, Marcus A; Sher, Alan; Germain, Ronald N.

Immunity ; 34(5): 807-19, 2011 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-21596592

13.

Even neurons are excited by Th17 cells.

Egen, Jackson G; Ouyang, Wenjun.

Immunity ; 33(3): 298-300, 2010 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-20870172

14.

Use of two-photon microscopy to study Leishmania major infection of the skin.

Carneiro, Matheus Batista; Hohman, Leah Shan; Egen, Jackson G; Peters, Nathan C.

Methods ; 127: 45-52, 2017 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-28434998

15.

CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis.

Jia, Guiquan; Chandriani, Sanjay; Abbas, Alexander R; DePianto, Daryle J; N'Diaye, Elsa N; Yaylaoglu, Murat B; Moore, Heather M; Peng, Ivan; DeVoss, Jason; Collard, Harold R; Wolters, Paul J; Egen, Jackson G; Arron, Joseph R.

Thorax ; 72(9): 780-787, 2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28250200

16.

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.

Tew, Gaik W; Hackney, Jason A; Gibbons, Deena; Lamb, Christopher A; Luca, Diana; Egen, Jackson G; Diehl, Lauri; Eastham Anderson, Jeff; Vermeire, Severine; Mansfield, John C; Feagan, Brian G; Panes, Julian; Baumgart, Daniel C; Schreiber, Stefan; Dotan, Iris; Sandborn, William J; Kirby, John A; Irving, Peter M; De Hertogh, Gert; Van Assche, Gert A; Rutgeerts, Paul; O'Byrne, Sharon; Hayday, Adrian; Keir, Mary E.

Gastroenterology ; 150(2): 477-87.e9, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26522261

17.

Pathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.

Torabi-Parizi, Parizad; Vrisekoop, Nienke; Kastenmuller, Wolfgang; Gerner, Michael Y; Egen, Jackson G; Germain, Ronald N.

J Immunol ; 192(4): 1651-1660, 2014 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-24431231

18.

Correction: LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8⁺ T Cells.

Kim, Aeryon; Han, Chia-Jung; Driver, Ian; Olow, Aleksandra; Sewell, Andrew K; Zhang, Zemin; Ouyang, Wenjun; Egen, Jackson G; Yu, Xin.

J Immunol ; 203(7): 2023-2024, 2019 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-31471523

19.

Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts.

Chandriani, Sanjay; DePianto, Daryle J; N'Diaye, Elsa N; Abbas, Alexander R; Jackman, Janet; Bevers, Jack; Ramirez-Carrozzi, Vladimir; Pappu, Rajita; Kauder, Steven E; Toy, Karen; Ha, Connie; Modrusan, Zora; Wu, Lawren C; Collard, Harold R; Wolters, Paul J; Egen, Jackson G; Arron, Joseph R.

J Immunol ; 193(1): 111-9, 2014 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-24879793

20.

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial.

Vermeire, Séverine; O'Byrne, Sharon; Keir, Mary; Williams, Marna; Lu, Timothy T; Mansfield, John C; Lamb, Christopher A; Feagan, Brian G; Panes, Julian; Salas, Azucena; Baumgart, Daniel C; Schreiber, Stefan; Dotan, Iris; Sandborn, William J; Tew, Gaik W; Luca, Diana; Tang, Meina T; Diehl, Lauri; Eastham-Anderson, Jeffrey; De Hertogh, Gert; Perrier, Clementine; Egen, Jackson G; Kirby, John A; van Assche, Gert; Rutgeerts, Paul.

Lancet ; 384(9940): 309-18, 2014 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-24814090

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