Pesquisa | BVS Violência e Saúde

1.

Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.

Devalaraja, Samir; To, Tsun Ki Jerrick; Folkert, Ian W; Natesan, Ramakrishnan; Alam, Md Zahidul; Li, Minghong; Tada, Yuma; Budagyan, Konstantin; Dang, Mai T; Zhai, Li; Lobel, Graham P; Ciotti, Gabrielle E; Eisinger-Mathason, T S Karin; Asangani, Irfan A; Weber, Kristy; Simon, M Celeste; Haldar, Malay.

Cell ; 180(6): 1098-1114.e16, 2020 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-32169218

2.

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy.

Li, Jinyang; Byrne, Katelyn T; Yan, Fangxue; Yamazoe, Taiji; Chen, Zeyu; Baslan, Timour; Richman, Lee P; Lin, Jeffrey H; Sun, Yu H; Rech, Andrew J; Balli, David; Hay, Ceire A; Sela, Yogev; Merrell, Allyson J; Liudahl, Shannon M; Gordon, Naomi; Norgard, Robert J; Yuan, Salina; Yu, Sixiang; Chao, Timothy; Ye, Shuai; Eisinger-Mathason, T S Karin; Faryabi, Robert B; Tobias, John W; Lowe, Scott W; Coussens, Lisa M; Wherry, E John; Vonderheide, Robert H; Stanger, Ben Z.

Immunity ; 49(1): 178-193.e7, 2018 07 17.

Artigo em Inglês | MEDLINE | ID: mdl-29958801

3.

Cancer research needs better databases.

Eisinger-Mathason, T S Karin.

Nature ; 610(7933): 607, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36284188

4.

Hypoxia and the Tumor Secretome.

Liu, Ying; Ciotti, Gabrielle E; Eisinger-Mathason, T S Karin.

Adv Exp Med Biol ; 1136: 57-69, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31201716

5.

Intratumoral oxygen gradients mediate sarcoma cell invasion.

Lewis, Daniel M; Park, Kyung Min; Tang, Vitor; Xu, Yu; Pak, Koreana; Eisinger-Mathason, T S Karin; Simon, M Celeste; Gerecht, Sharon.

Proc Natl Acad Sci U S A ; 113(33): 9292-7, 2016 08 16.

Artigo em Inglês | MEDLINE | ID: mdl-27486245

6.

Sustained activation of the HER1-ERK1/2-RSK signaling pathway controls myoepithelial cell fate in human mammary tissue.

Pasic, Lejla; Eisinger-Mathason, T S Karin; Velayudhan, Bisi T; Moskaluk, Christopher A; Brenin, David R; Macara, Ian G; Lannigan, Deborah A.

Genes Dev ; 25(15): 1641-53, 2011 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-21828273

7.

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis.

Eisinger-Mathason, T S Karin; Mucaj, Vera; Biju, Kevin M; Nakazawa, Michael S; Gohil, Mercy; Cash, Timothy P; Yoon, Sam S; Skuli, Nicolas; Park, Kyung Min; Gerecht, Sharon; Simon, M Celeste.

Proc Natl Acad Sci U S A ; 112(26): E3402-11, 2015 Jun 30.

Artigo em Inglês | MEDLINE | ID: mdl-26080399

8.

Targeting the Hippo pathway: Clinical implications and therapeutics.

Ye, Shuai; Eisinger-Mathason, T S Karin.

Pharmacol Res ; 103: 270-8, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26678601

9.

Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival.

Eisinger-Mathason, T S Karin; Andrade, Josefa; Groehler, Angela L; Clark, David E; Muratore-Schroeder, Tara L; Pasic, Lejla; Smith, Jeffrey A; Shabanowitz, Jeffrey; Hunt, Donald F; Macara, Ian G; Lannigan, Deborah A.

Mol Cell ; 31(5): 722-36, 2008 Sep 05.

Artigo em Inglês | MEDLINE | ID: mdl-18775331

10.

Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer.

Shay, Jessica E S; Imtiyaz, Hongxia Z; Sivanand, Sharanya; Durham, Amy C; Skuli, Nicolas; Hsu, Sarah; Mucaj, Vera; Eisinger-Mathason, T S Karin; Krock, Bryan L; Giannoukos, Dionysios N; Simon, M Celeste.

Carcinogenesis ; 35(5): 1067-77, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24408928

11.

Age-dependent loss of HAPLN1 erodes vascular integrity via indirect upregulation of endothelial ICAM1 in melanoma.

Marino-Bravante, Gloria E; Carey, Alexis E; Hüser, Laura; Dixit, Agrani; Wang, Vania; Kaur, Amanpreet; Liu, Ying; Ding, Supeng; Schnellmann, Rahel; Gerecht, Sharon; Gu, Luo; Eisinger-Mathason, T S Karin; Chhabra, Yash; Weeraratna, Ashani T.

Nat Aging ; 4(3): 350-363, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38472454

12.

Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.

Liu, Ying; Murazzi, Ileana; Fuller, Ashley M; Pan, Hehai; Irizarry-Negron, Valerie M; Devine, Ann; Katti, Rohan; Skuli, Nicolas; Ciotti, Gabrielle E; Pak, Koreana; Pack, Michael A; Simon, M Celeste; Weber, Kristy; Cooper, Kumarasen; Eisinger-Mathason, T S Karin.

Cancer Res ; 84(7): 977-993, 2024 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-38335278

13.

Small extracellular vesicles promote stiffness-mediated metastasis.

Sneider, Alexandra; Liu, Ying; Starich, Bartholomew; Du, Wenxuan; Marar, Carolyn; Faqih, Najwa; Ciotti, Gabrielle E; Kim, Joo Ho; Krishnan, Sejal; Ibrahim, Salma; Igboko, Muna; Locke, Alexus; Lewis, Daniel M; Hong, Hanna; Karl, Michelle; Vij, Raghav; Russo, Gabriella C; Nair, Praful; Gómez-de-Mariscal, Estibaliz; Habibi, Mehran; Muñoz-Barrutia, Arrate; Gu, Luo; Eisinger-Mathason, T S Karin; Wirtz, Denis.

bioRxiv ; 2024 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-37425743

14.

Small Extracellular Vesicles Promote Stiffness-mediated Metastasis.

Sneider, Alexandra; Liu, Ying; Starich, Bartholomew; Du, Wenxuan; Nair, Praful R; Marar, Carolyn; Faqih, Najwa; Ciotti, Gabrielle E; Kim, Joo Ho; Krishnan, Sejal; Ibrahim, Salma; Igboko, Muna; Locke, Alexus; Lewis, Daniel M; Hong, Hanna; Karl, Michelle N; Vij, Raghav; Russo, Gabriella C; Gómez-de-Mariscal, Estibaliz; Habibi, Mehran; Muñoz-Barrutia, Arrate; Gu, Luo; Eisinger-Mathason, T S Karin; Wirtz, Denis.

Cancer Res Commun ; 4(5): 1240-1252, 2024 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-38630893

15.

Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment.

Fuller, Ashley M; Pruitt, Hawley C; Liu, Ying; Irizarry-Negron, Valerie M; Pan, Hehai; Song, Hoogeun; DeVine, Ann; Katti, Rohan S; Devalaraja, Samir; Ciotti, Gabrielle E; Gonzalez, Michael V; Williams, Erik F; Murazzi, Ileana; Ntekoumes, Dimitris; Skuli, Nicolas; Hakonarson, Hakon; Zabransky, Daniel J; Trevino, Jose G; Weeraratna, Ashani; Weber, Kristy; Haldar, Malay; Fraietta, Joseph A; Gerecht, Sharon; Eisinger-Mathason, T S Karin.

J Clin Invest ; 2024 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-38652549

16.

Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1α.

Kim, Yeo-Jung; Lee, Hae-June; Kim, Tae-Min; Eisinger-Mathason, T S Karin; Zhang, Alexia Y; Schmidt, Benjamin; Karl, Daniel L; Nakazawa, Michael S; Park, Peter J; Simon, M Celeste; Yoon, Sam S.

Int J Cancer ; 132(1): 29-41, 2013 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-22684860

17.

Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma.

Fuller, Ashley M; DeVine, Ann; Murazzi, Ileana; Mason, Nicola J; Weber, Kristy; Eisinger-Mathason, T S Karin.

Cell Oncol (Dordr) ; 45(6): 1277-1295, 2022 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-36181640

18.

Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1.

Deng, Qu; Natesan, Ramakrishnan; Cidre-Aranaz, Florencia; Arif, Shehbeel; Liu, Ying; Rasool, Reyaz Ur; Wang, Pei; Mitchell-Velasquez, Erick; Das, Chandan Kanta; Vinca, Endrit; Cramer, Zvi; Grohar, Patrick J; Chou, Margaret; Kumar-Sinha, Chandan; Weber, Kristy; Eisinger-Mathason, T S Karin; Grillet, Nicolas; Grünewald, Thomas G. P.; Asangani, Irfan A.

Cell Rep ; 39(11): 110971, 2022 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-35705030

19.

Virtual screening for small-molecule pathway regulators by image-profile matching.

Rohban, Mohammad H; Fuller, Ashley M; Tan, Ceryl; Goldstein, Jonathan T; Syangtan, Deepsing; Gutnick, Amos; DeVine, Ann; Nijsure, Madhura P; Rigby, Megan; Sacher, Joshua R; Corsello, Steven M; Peppler, Grace B; Bogaczynska, Marta; Boghossian, Andrew; Ciotti, Gabrielle E; Hands, Allison T; Mekareeya, Aroonroj; Doan, Minh; Gale, Jennifer P; Derynck, Rik; Turbyville, Thomas; Boerckel, Joel D; Singh, Shantanu; Kiessling, Laura L; Schwarz, Thomas L; Varelas, Xaralabos; Wagner, Florence F; Kafri, Ran; Eisinger-Mathason, T S Karin; Carpenter, Anne E.

Cell Syst ; 13(9): 724-736.e9, 2022 09 21.

Artigo em Inglês | MEDLINE | ID: mdl-36057257

20.

TGFß and Hippo Pathways Cooperate to Enhance Sarcomagenesis and Metastasis through the Hyaluronan-Mediated Motility Receptor (HMMR).

Ye, Shuai; Liu, Ying; Fuller, Ashley M; Katti, Rohan; Ciotti, Gabrielle E; Chor, Susan; Alam, Md Zahidul; Devalaraja, Samir; Lorent, Kristin; Weber, Kristy; Haldar, Malay; Pack, Michael A; Eisinger-Mathason, T S Karin.

Mol Cancer Res ; 18(4): 560-573, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31988250

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