Detalhe da pesquisa
1.
Establishment of an In Bacterio Assay for the Assessment of Carbon Storage Regulator A (CsrA) Inhibitors.
Chembiochem
; 24(16): e202300369, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37435861
2.
NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain.
J Am Chem Soc
; 144(29): 13060-13065, 2022 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830336
3.
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages.
Antimicrob Agents Chemother
; 66(12): e0103222, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346232
4.
Modeling the Effect of Hydrophobicity on the Passive Permeation of Solutes across a Bacterial Model Membrane.
J Chem Inf Model
; 62(20): 5023-5033, 2022 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36214845
5.
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
FASEB J
; 34(1): 316-332, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914675
6.
Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P.â aeruginosa Biofilm Infections.
Angew Chem Int Ed Engl
; 59(26): 10292-10296, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243047
7.
Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor.
Biol Chem
; 400(3): 333-342, 2019 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657738
8.
Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum.
Chemistry
; 25(37): 8894-8902, 2019 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31012978
9.
Concepts and Core Principles of Fragment-Based Drug Design.
Molecules
; 24(23)2019 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31779114
10.
The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem
; 19(14): 1531-1544, 2018 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29722462
11.
Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents.
Pharm Res
; 36(1): 22, 2018 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30519925
12.
Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers.
Beilstein J Org Chem
; 14: 2627-2645, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30410625
13.
Single-domain antibodies for biomedical applications.
Immunopharmacol Immunotoxicol
; 38(1): 21-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551147
14.
An Apoptosis-Inducing Peptidic Heptad That Efficiently Clusters Death Receptorâ 5.
Angew Chem Int Ed Engl
; 55(16): 5085-9, 2016 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26991930
15.
Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors.
Chembiochem
; 16(17): 2441-4, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26426719
16.
From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa.
Org Biomol Chem
; 12(32): 6094-104, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24909330
17.
Potent inhibitors of human matriptase-1 based on the scaffold of sunflower trypsin inhibitor.
J Pept Sci
; 20(6): 415-20, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24723440
18.
Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road?
Int J Nanomedicine
; 19: 3861-3890, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38708178
19.
Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target.
Front Biosci (Landmark Ed)
; 29(1): 41, 2024 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38287808
20.
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Nat Commun
; 15(1): 1173, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332002