Pesquisa | BVS Violência e Saúde

1.

The complexity of transferring genetic information.

Strader, Lucia C; Staller, Max V; Willis, Anne E; Faulkner, Geoffrey J; Beggs, Jean D; Cech, Thomas R.

Mol Cell ; 83(3): 320-323, 2023 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-36736305

2.

Ubiquitous L1 mosaicism in hippocampal neurons.

Upton, Kyle R; Gerhardt, Daniel J; Jesuadian, J Samuel; Richardson, Sandra R; Sánchez-Luque, Francisco J; Bodea, Gabriela O; Ewing, Adam D; Salvador-Palomeque, Carmen; van der Knaap, Marjo S; Brennan, Paul M; Vanderver, Adeline; Faulkner, Geoffrey J.

Cell ; 161(2): 228-39, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25860606

3.

HUSH, retrotransposon RNA, you're NEXT to decay.

Faulkner, Geoffrey J.

Mol Cell ; 82(9): 1610-1612, 2022 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-35523126

4.

Transient naive reprogramming corrects hiPS cells functionally and epigenetically.

Buckberry, Sam; Liu, Xiaodong; Poppe, Daniel; Tan, Jia Ping; Sun, Guizhi; Chen, Joseph; Nguyen, Trung Viet; de Mendoza, Alex; Pflueger, Jahnvi; Frazer, Thomas; Vargas-Landín, Dulce B; Paynter, Jacob M; Smits, Nathan; Liu, Ning; Ouyang, John F; Rossello, Fernando J; Chy, Hun S; Rackham, Owen J L; Laslett, Andrew L; Breen, James; Faulkner, Geoffrey J; Nefzger, Christian M; Polo, Jose M; Lister, Ryan.

Nature ; 620(7975): 863-872, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37587336

5.

Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.

Shukla, Ruchi; Upton, Kyle R; Muñoz-Lopez, Martin; Gerhardt, Daniel J; Fisher, Malcolm E; Nguyen, Thu; Brennan, Paul M; Baillie, J Kenneth; Collino, Agnese; Ghisletti, Serena; Sinha, Shruti; Iannelli, Fabio; Radaelli, Enrico; Dos Santos, Alexandre; Rapoud, Delphine; Guettier, Catherine; Samuel, Didier; Natoli, Gioacchino; Carninci, Piero; Ciccarelli, Francesca D; Garcia-Perez, Jose Luis; Faivre, Jamila; Faulkner, Geoffrey J.

Cell ; 153(1): 101-11, 2013 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-23540693

6.

Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling.

Ewing, Adam D; Smits, Nathan; Sanchez-Luque, Francisco J; Faivre, Jamila; Brennan, Paul M; Richardson, Sandra R; Cheetham, Seth W; Faulkner, Geoffrey J.

Mol Cell ; 80(5): 915-928.e5, 2020 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-33186547

7.

Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis.

Madrid, Lidia I; Hafey, Katelyn; Bandhavkar, Saurabh; Bodea, Gabriela O; Jimenez-Martin, Javier; Milne, Michael; Walker, Tara L; Faulkner, Geoffrey J; Coulson, Elizabeth J; Jhaveri, Dhanisha J.

Development ; 151(1)2024 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-38063486

8.

LINE-1 Evasion of Epigenetic Repression in Humans.

Sanchez-Luque, Francisco J; Kempen, Marie-Jeanne H C; Gerdes, Patricia; Vargas-Landin, Dulce B; Richardson, Sandra R; Troskie, Robin-Lee; Jesuadian, J Samuel; Cheetham, Seth W; Carreira, Patricia E; Salvador-Palomeque, Carmen; García-Cañadas, Marta; Muñoz-Lopez, Martin; Sanchez, Laura; Lundberg, Mischa; Macia, Angela; Heras, Sara R; Brennan, Paul M; Lister, Ryan; Garcia-Perez, Jose L; Ewing, Adam D; Faulkner, Geoffrey J.

Mol Cell ; 75(3): 590-604.e12, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31230816

9.

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development.

Gerdes, Patricia; Chan, Dorothy; Lundberg, Mischa; Sanchez-Luque, Francisco J; Bodea, Gabriela O; Ewing, Adam D; Faulkner, Geoffrey J; Richardson, Sandra R.

Genome Res ; 33(9): 1465-1481, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37798118

10.

Overcoming challenges and dogmas to understand the functions of pseudogenes.

Cheetham, Seth W; Faulkner, Geoffrey J; Dinger, Marcel E.

Nat Rev Genet ; 21(3): 191-201, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31848477

11.

Somatic retrotransposition in the developing rhesus macaque brain.

Billon, Victor; Sanchez-Luque, Francisco J; Rasmussen, Jay; Bodea, Gabriela O; Gerhardt, Daniel J; Gerdes, Patricia; Cheetham, Seth W; Schauer, Stephanie N; Ajjikuttira, Prabha; Meyer, Thomas J; Layman, Cora E; Nevonen, Kimberly A; Jansz, Natasha; Garcia-Perez, Jose L; Richardson, Sandra R; Ewing, Adam D; Carbone, Lucia; Faulkner, Geoffrey J.

Genome Res ; 32(7): 1298-1314, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35728967

12.

Viral genome sequencing methods: benefits and pitfalls of current approaches.

Jansz, Natasha; Faulkner, Geoffrey J.

Biochem Soc Trans ; 2024 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-38747720

13.

Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation.

Zadran, Bassier; Sudhindar, Praveen Dhondurao; Wainwright, Daniel; Bury, Yvonne; Luli, Saimir; Howarth, Rachel; McCain, Misti Vanette; Watson, Robyn; Huet, Hannah; Palinkas, Fanni; Berlinguer-Palmini, Rolando; Casement, John; Mann, Derek A; Oakley, Fiona; Lunec, John; Reeves, Helen; Faulkner, Geoffrey J; Shukla, Ruchi.

Br J Cancer ; 128(7): 1236-1248, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36707636

14.

Retrotransposons: still mobile in humans.

Faulkner, Geoffrey J.

Nat Rev Genet ; 23(8): 458-459, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35361925

15.

Processed pseudogenes: A substrate for evolutionary innovation: Retrotransposition contributes to genome evolution by propagating pseudogene sequences with rich regulatory potential throughout the genome.

Troskie, Robin-Lee; Faulkner, Geoffrey J; Cheetham, Seth W.

Bioessays ; 43(11): e2100186, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34569081

16.

L1 retrotransposons and somatic mosaicism in the brain.

Richardson, Sandra R; Morell, Santiago; Faulkner, Geoffrey J.

Annu Rev Genet ; 48: 1-27, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25036377

17.

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis.

Schauer, Stephanie N; Carreira, Patricia E; Shukla, Ruchi; Gerhardt, Daniel J; Gerdes, Patricia; Sanchez-Luque, Francisco J; Nicoli, Paola; Kindlova, Michaela; Ghisletti, Serena; Santos, Alexandre Dos; Rapoud, Delphine; Samuel, Didier; Faivre, Jamila; Ewing, Adam D; Richardson, Sandra R; Faulkner, Geoffrey J.

Genome Res ; 28(5): 639-653, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29643204

18.

Visualization and analysis of RNA-Seq assembly graphs.

Nazarie, Fahmi W; Shih, Barbara; Angus, Tim; Barnett, Mark W; Chen, Sz-Hau; Summers, Kim M; Klein, Karsten; Faulkner, Geoffrey J; Saini, Harpreet K; Watson, Mick; Dongen, Stijn van; Enright, Anton J; Freeman, Tom C.

Nucleic Acids Res ; 47(14): 7262-7275, 2019 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-31305886

19.

L1 Mosaicism in Mammals: Extent, Effects, and Evolution.

Faulkner, Geoffrey J; Garcia-Perez, Jose L.

Trends Genet ; 33(11): 802-816, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-28797643

20.

Heritable L1 retrotransposition in the mouse primordial germline and early embryo.

Richardson, Sandra R; Gerdes, Patricia; Gerhardt, Daniel J; Sanchez-Luque, Francisco J; Bodea, Gabriela-Oana; Muñoz-Lopez, Martin; Jesuadian, J Samuel; Kempen, Marie-Jeanne H C; Carreira, Patricia E; Jeddeloh, Jeffrey A; Garcia-Perez, Jose L; Kazazian, Haig H; Ewing, Adam D; Faulkner, Geoffrey J.

Genome Res ; 27(8): 1395-1405, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28483779

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