Detalhe da pesquisa
1.
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists.
Molecules
; 28(6)2023 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36985811
2.
Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116.
Phytochem Anal
; 30(5): 524-534, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31168900
3.
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
Molecules
; 24(6)2019 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30884797
4.
Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside.
Molecules
; 24(9)2019 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31052163
5.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Biochem Pharmacol
; 223: 116134, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38494064
6.
Correction to "Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders".
ACS Omega
; 8(47): 45163, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38046314
7.
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders.
ACS Omega
; 8(6): 5983-5994, 2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36816679
8.
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches.
Plants (Basel)
; 11(13)2022 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35807623
9.
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests.
Biomolecules
; 11(10)2021 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34680124
10.
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain.
Front Chem
; 8: 572885, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33195060
11.
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis.
ACS Med Chem Lett
; 11(5): 818-824, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435390
12.
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.
Sci Rep
; 9(1): 2504, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792450
13.
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.
ACS Med Chem Lett
; 10(4): 504-510, 2019 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30996787
14.
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.
ACS Med Chem Lett
; 10(4): 407-412, 2019 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30996771
15.
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.
Sci Rep
; 7: 43290, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233865
16.
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.
Steroids
; 105: 59-67, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607331
17.
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.
Sci Rep
; 6: 29320, 2016 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381677
18.
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.
Sci Rep
; 6: 19008, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740187
19.
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.
J Med Chem
; 57(20): 8477-95, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25247751