Detalhe da pesquisa
1.
PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly.
Mol Cell
; 83(22): 4123-4140.e12, 2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37848033
2.
A Fluorescence-Based Assay for N5 -Carboxyaminoimidazole Ribonucleotide Mutase.
Chembiochem
; 24(18): e202300347, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474455
3.
An Aniline-Substituted Bile Salt Analog Protects both Mice and Hamsters from Multiple Clostridioides difficile Strains.
Antimicrob Agents Chemother
; 66(1): e0143521, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780262
4.
Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5ß-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile.
Bioorg Med Chem
; 52: 116503, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837818
5.
Isatins Inhibit N5-CAIR Synthetase by a Substrate Depletion Mechanism.
Biochemistry
; 58(17): 2260-2268, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30964980
6.
Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles.
AAPS PharmSciTech
; 19(8): 3561-3570, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30255472
7.
Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase.
Biochemistry
; 52(37): 6559-67, 2013 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23899325
8.
The design, synthesis, and inhibition of Clostridioides difficile spore germination by acyclic and bicyclic tertiary amide analogs of cholate.
Eur J Med Chem
; 261: 115788, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703709
9.
Cyclam-based polymeric copper chelators for gene delivery and potential PET imaging.
Biomacromolecules
; 13(10): 3220-7, 2012 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23004346
10.
Examination of a synthetic benzophenone membrane-targeted antibiotic.
Org Biomol Chem
; 9(18): 6367-72, 2011 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21792399
11.
The ATP-grasp enzymes.
Bioorg Chem
; 39(5-6): 185-91, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21920581
12.
Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase .
Biochemistry
; 49(4): 752-60, 2010 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20050602
13.
Solution-phase parallel synthesis of novel membrane-targeted antibiotics.
J Comb Chem
; 12(1): 151-60, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19928911
14.
Benzo(h)quinoline derivatives as G-quadruplex binding agents.
Bioorg Med Chem Lett
; 19(6): 1584-7, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19243943
15.
Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase.
Bioorg Med Chem
; 17(2): 794-803, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19095456
16.
Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening.
Bioorg Med Chem
; 17(9): 3317-23, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19362848
17.
Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.
Cells
; 8(11)2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31683936
18.
Structural analysis of the active site geometry of N5-carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry
; 47(50): 13346-53, 2008 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19053251
19.
The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile.
J Med Chem
; 61(15): 6759-6778, 2018 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30004695
20.
Gene delivery to dendritic cells facilitated by a tumor necrosis factor alpha-competing peptide.
Mol Immunol
; 41(8): 741-9, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15234553