Detalhe da pesquisa
1.
Nature as blueprint: Global phenotype engineering of CHO production cells based on a multi-omics comparison with plasma cells.
Metab Eng
; 83: 110-122, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38561148
2.
Multi-lipase gene knockdown in Chinese hamster ovary cells using artificial microRNAs to reduce host cell protein mediated polysorbate degradation.
Biotechnol Bioeng
; 121(1): 329-340, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37743807
3.
Tailoring polishing steps for effective removal of polysorbate-degrading host cell proteins in antibody purification.
Biotechnol Bioeng
; 2024 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38853584
4.
Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell-Derived Cells.
Mol Cell Proteomics
; 21(10): 100278, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35934186
5.
Low-energy electron microscopy intensity-voltage data - Factorization, sparse sampling and classification.
J Microsc
; 289(2): 91-106, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36288376
6.
Reflection Machines: Supporting Effective Human Oversight Over Medical Decision Support Systems.
Camb Q Healthc Ethics
; : 1-10, 2023 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36624620
7.
Loss of a newly discovered microRNA in Chinese hamster ovary cells leads to upregulation of N-glycolylneuraminic acid sialylation on monoclonal antibodies.
Biotechnol Bioeng
; 119(3): 832-844, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935124
8.
Decline in Atlantic wolffish Anarhichas lupus in the North Sea: Impacts of fishing pressure and climate change.
J Fish Biol
; 100(1): 253-267, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34751448
9.
Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERAD.
Biotechnol Bioeng
; 117(1): 5-16, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31631329
10.
Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5.
Cell Mol Life Sci
; 76(3): 539-559, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30392041
11.
Pre-stage perfusion and ultra-high seeding cell density in CHO fed-batch culture: a case study for process intensification guided by systems biotechnology.
Bioprocess Biosyst Eng
; 43(8): 1431-1443, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32266469
12.
Stable miRNA overexpression in human CAP cells: Engineering alternative production systems for advanced manufacturing of biologics using miR-136 and miR-3074.
Biotechnol Bioeng
; 115(8): 2027-2038, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29665036
13.
The Impact of Prehospital Tranexamic Acid on Blood Coagulation in Trauma Patients.
Anesth Analg
; 126(2): 522-529, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29239953
14.
RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish.
J Cell Sci
; 128(16): 3030-40, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26116573
15.
miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
Biotechnol Bioeng
; 114(7): 1495-1510, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28262952
16.
Reverse U-to-C editing exceeds C-to-U RNA editing in some ferns - a monilophyte-wide comparison of chloroplast and mitochondrial RNA editing suggests independent evolution of the two processes in both organelles.
BMC Evol Biol
; 16(1): 134, 2016 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27329857
17.
Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells.
Biotechnol Bioeng
; 113(4): 830-41, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26461143
18.
Atlas of the clinical genetics of human dilated cardiomyopathy.
Eur Heart J
; 36(18): 1123-35a, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25163546
19.
Horsetails are the sister group to all other monilophytes and Marattiales are sister to leptosporangiate ferns.
Mol Phylogenet Evol
; 90: 140-9, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25999055
20.
miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality.
Biotechnol Bioeng
; 112(10): 2142-53, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25997799