Detalhe da pesquisa
1.
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Cell
; 155(2): 397-409, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24120138
2.
Lack of Evidence for PKM2 Protein Kinase Activity.
Mol Cell
; 59(5): 850-7, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26300261
3.
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells.
Mol Cell
; 55(2): 253-63, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882210
4.
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Nature
; 520(7547): 363-7, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855294
5.
Increased PHGDH expression promotes aberrant melanin accumulation.
BMC Cancer
; 19(1): 723, 2019 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331318
6.
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Nat Chem Biol
; 12(6): 452-8, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27110680
7.
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat Chem Biol
; 8(10): 839-47, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922757
8.
MYTX-011: a pH-dependent anti-cMET antibody-drug conjugate designed for enhanced payload delivery to cMET expressing tumor cells.
Mol Cancer Ther
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38684230
9.
MYTX-011: A pH-Dependent Anti-c-MET Antibody-Drug Conjugate Designed for Enhanced Payload Delivery to c-MET-Expressing Tumor Cells.
Mol Cancer Ther
; : OF1-OF12, 2024 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38853438
10.
Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Nat Chem Biol
; 12(8): 656, 2016 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27434767
11.
Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation.
Nat Metab
; 1(9): 861-867, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31598584
12.
An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.
Cancer Metab
; 3: 5, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25926973
13.
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Nat Med
; 20(10): 1193-1198, 2014 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25261994
14.
Seeing the Warburg effect in the developing retina.
Nat Cell Biol
; 14(8): 790-1, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22854814