Detalhe da pesquisa
1.
Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures.
Biotechnol Bioeng
; 112(1): 141-55, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25042542
2.
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.
Proc Natl Acad Sci U S A
; 109(14): 5364-9, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22434908
3.
Cellular responses to individual amino-acid depletion in antibody-expressing and parental CHO cell lines.
Biotechnol Bioeng
; 111(5): 965-79, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24254056
4.
Small-molecule inducers of insulin expression in pancreatic alpha-cells.
Proc Natl Acad Sci U S A
; 107(34): 15099-104, 2010 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20696901
5.
Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression.
J Biotechnol
; 212: 106-15, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26325199
6.
Gene expression measurements normalized to cell number reveal large scale differences due to cell size changes, transcriptional amplification and transcriptional repression in CHO cells.
J Biotechnol
; 189: 58-69, 2014 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25194670
7.
Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming.
PLoS One
; 9(4): e95194, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24759943
8.
Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses.
J Biomol Screen
; 19(5): 771-81, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464433
9.
GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.
PLoS One
; 7(1): e28808, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22242153
10.
A human islet cell culture system for high-throughput screening.
J Biomol Screen
; 17(4): 509-18, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22156222