Detalhe da pesquisa
1.
A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.
Blood
; 141(25): 3109-3121, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947859
2.
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell
; 132(3): 397-409, 2008 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18267072
3.
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.
PLoS Pathog
; 16(8): e1008230, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32797076
4.
NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition.
Blood
; 134(8): 699-708, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133602
5.
Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood-brain barrier damage, and inflammation.
Brain Behav Immun
; 93: 288-298, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33401017
6.
Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis.
PLoS Pathog
; 10(9): e1004338, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211214
7.
Hairy cell leukemia coexistent with chronic lymphocytic leukemia.
Blood
; 133(11): 1264, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30872271
8.
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Blood
; 122(25): 4094-106, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24159172
9.
A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera).
J Med Entomol
; 52(3): 351-8, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334808
10.
Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P.
Proc Natl Acad Sci U S A
; 109(14): 5429-34, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22431641
11.
Salivary antigen-5/CAP family members are Cu2+-dependent antioxidant enzymes that scavenge O2â. and inhibit collagen-induced platelet aggregation and neutrophil oxidative burst.
J Biol Chem
; 288(20): 14341-14361, 2013 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23564450
12.
Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate.
Arterioscler Thromb Vasc Biol
; 33(12): 2759-70, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24092749
13.
Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J Biol Chem
; 287(14): 10967-76, 2012 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22311975
14.
Aegyptin inhibits collagen-induced coagulation activation in vitro and thromboembolism in vivo.
Biochem Biophys Res Commun
; 436(2): 235-9, 2013 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23726920
15.
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.
Blood
; 117(2): 736-44, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940421
16.
The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
PLoS Biol
; 8(11): e1000547, 2010 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21152418
17.
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Arterioscler Thromb Vasc Biol
; 32(9): 2185-98, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22796577
18.
Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria.
Arterioscler Thromb Vasc Biol
; 32(3): 786-98, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22116094
19.
SARS-CoV-2 infection results in upregulation of Plasminogen Activator Inhibitor-1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated with disease severity.
EJHaem
; 4(2): 324-338, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37206290
20.
Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
J Biol Chem
; 286(32): 27998-8010, 2011 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21673107