Detalhe da pesquisa
1.
A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli.
Proc Natl Acad Sci U S A
; 117(17): 9508-9518, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32291345
2.
Distinct Autocatalytic α- N-Methylating Precursors Expand the Borosin RiPP Family of Peptide Natural Products.
J Am Chem Soc
; 141(24): 9637-9644, 2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117659
3.
Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products.
Nat Chem Biol
; 13(8): 833-835, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28581484
4.
Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis.
J Ind Microbiol Biotechnol
; 46(3-4): 551-563, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30627933
5.
An Orthogonal D2 O-Based Induction System that Provides Insights into d-Amino Acid Pattern Formation by Radical S-Adenosylmethionine Peptide Epimerases.
Angew Chem Int Ed Engl
; 56(3): 762-766, 2017 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27958669
6.
Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement.
Proc Natl Acad Sci U S A
; 109(7): 2308-13, 2012 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22308359
7.
Exploring the role of conformational heterogeneity in cis-autoproteolytic activation of ThnT.
Biochemistry
; 53(26): 4273-81, 2014 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24933323
8.
Radical S-adenosyl methionine epimerases: regioselective introduction of diverse D-amino acid patterns into peptide natural products.
Angew Chem Int Ed Engl
; 53(32): 8503-7, 2014 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24943072
9.
Discovery of Borosin Catalytic Strategies and Function through Bioinformatic Profiling.
ACS Chem Biol
; 19(5): 1116-1124, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38695893
10.
Computationally guided exploration of borosin biosynthetic strategies.
bioRxiv
; 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260703
11.
Diverse Protein Architectures and α-N-Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters.
ACS Chem Biol
; 17(4): 908-917, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35297605
12.
TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes.
mSystems
; 7(6): e0092522, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36378489
13.
Definition of the common and divergent steps in carbapenem ß-lactam antibiotic biosynthesis.
Chembiochem
; 12(14): 2159-65, 2011 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913298
14.
The Catalytic Diversity of Multimodular Polyketide Synthases: Natural Product Biosynthesis Beyond Textbook Assembly Rules.
Top Curr Chem
; 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360321
15.
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
Proc Natl Acad Sci U S A
; 105(32): 11128-33, 2008 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18678912
16.
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis.
Nat Commun
; 12(1): 5355, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34504067
17.
Enzyme-mediated backbone N-methylation in ribosomally encoded peptides.
Methods Enzymol
; 656: 429-458, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34325794
18.
Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics.
J Am Chem Soc
; 132(1): 12-3, 2010 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20017478
19.
Genome mining- and synthetic biology-enabled production of hypermodified peptides.
Nat Chem
; 11(10): 931-939, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501509
20.
Cobalamin-Dependent C-Methyltransferases From Marine Microbes: Accessibility via Rhizobia Expression.
Methods Enzymol
; 604: 259-286, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779655