Pesquisa | BVS Violência e Saúde

1.

Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs.

Padilla, Cristina M; Valenzi, Eleanor; Tabib, Tracy; Nazari, Banafsheh; Sembrat, John; Rojas, Mauricio; Fuschiotti, Patrizia; Lafyatis, Robert.

Rheumatology (Oxford) ; 63(3): 837-845, 2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-37310903

2.

Genome-wide transcriptome analysis of the STAT6-regulated genes in advanced-stage cutaneous T-cell lymphoma.

Gaydosik, Alyxzandria M; Queen, Dawn S; Trager, Megan H; Akilov, Oleg E; Geskin, Larisa J; Fuschiotti, Patrizia.

Blood ; 136(15): 1748-1759, 2020 10 08.

Artigo em Inglês | MEDLINE | ID: mdl-32438399

3.

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis.

Gaydosik, Alyxzandria M; Tabib, Tracy; Domsic, Robyn; Khanna, Dinesh; Lafyatis, Robert; Fuschiotti, Patrizia.

Ann Rheum Dis ; 80(11): 1453-1460, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34031030

4.

14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in T_C2 and CD8⁺ lymphocytes from patients with scleroderma.

Cascio, Sandra; Medsger, Thomas A; Hawse, William F; Watkins, Simon C; Milcarek, Christine; Moreland, Larry W; Lafyatis, Robert A; Fuschiotti, Patrizia.

J Allergy Clin Immunol ; 142(1): 109-119.e6, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29155097

5.

T cells and cytokines in systemic sclerosis.

Fuschiotti, Patrizia.

Curr Opin Rheumatol ; 30(6): 594-599, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30234723

6.

Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation.

Geskin, Larisa J; Viragova, Sara; Stolz, Donna B; Fuschiotti, Patrizia.

Blood ; 125(18): 2798-805, 2015 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-25628470

7.

Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis.

Fuschiotti, Patrizia; Larregina, Adriana T; Ho, Johnan; Feghali-Bostwick, Carol; Medsger, Thomas A.

Arthritis Rheum ; 65(1): 236-46, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23001877

8.

The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesis.

Gaydosik, Alyxzandria M; Stonesifer, Connor J; Tabib, Tracy; Lafyatis, Robert; Geskin, Larisa J; Fuschiotti, Patrizia.

JCI Insight ; 8(19)2023 10 09.

Artigo em Inglês | MEDLINE | ID: mdl-37669110

9.

Cell Type-Specific Biomarkers of Systemic Sclerosis Disease Severity Capture Cell-Intrinsic and Cell-Extrinsic Circuits.

Berkowitz, Jacob S; Tabib, Tracy; Xiao, Hanxi; Sadej, Gabrielle M; Khanna, Dinesh; Fuschiotti, Patrizia; Lafyatis, Robert A; Das, Jishnu.

Arthritis Rheumatol ; 75(10): 1819-1830, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37096444

10.

GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production.

Medsger, Thomas A; Ivanco, Dana E; Kardava, Lela; Morel, Penelope A; Lucas, Mary R; Fuschiotti, Patrizia.

Arthritis Rheum ; 63(6): 1738-47, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21638273

11.

Single-Cell RNA Sequencing Unveils the Clonal and Transcriptional Landscape of Cutaneous T-Cell Lymphomas.

Gaydosik, Alyxzandria M; Stonesifer, Connor J; Khaleel, Alexandra E; Geskin, Larisa J; Fuschiotti, Patrizia.

Clin Cancer Res ; 28(12): 2610-2622, 2022 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-35421230

12.

Role of IL-13 in systemic sclerosis.

Fuschiotti, Patrizia.

Cytokine ; 56(3): 544-9, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-21920770

13.

Dynamic aspects of TCRalpha gene recombination: qualitative and quantitative assessments of the TCRalpha chain repertoire in man and mouse.

Jouvin-Marche, Evelyne; Fuschiotti, Patrizia; Marche, Patrice Noël.

Adv Exp Med Biol ; 650: 82-92, 2009.

Artigo em Inglês | MEDLINE | ID: mdl-19731803

14.

Editorial: The underlying pathophysiology and therapeutic approaches for cutaneous T-cell lymphoma.

Fuschiotti, Patrizia.

Front Immunol ; 15: 1383024, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38469302

15.

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors.

Gaydosik, Alyxzandria M; Tabib, Tracy; Geskin, Larisa J; Bayan, Claire-Audrey; Conway, James F; Lafyatis, Robert; Fuschiotti, Patrizia.

Clin Cancer Res ; 25(14): 4443-4454, 2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31010835

16.

Analysis of the TCR alpha-chain rearrangement profile in human T lymphocytes.

Fuschiotti, Patrizia; Pasqual, Nicolas; Hierle, Vivien; Borel, Eve; London, Jacqueline; Marche, Patrice Noël; Jouvin-Marche, Evelyne.

Mol Immunol ; 44(13): 3380-8, 2007 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-17391765

17.

Current perspectives on the role of CD8+ T cells in systemic sclerosis.

Fuschiotti, Patrizia.

Immunol Lett ; 195: 55-60, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-28987475

18.

Skin-Resident Effector Memory CD8⁺CD28^- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.

Li, Gang; Larregina, Adriana T; Domsic, Robyn T; Stolz, Donna B; Medsger, Thomas A; Lafyatis, Robert; Fuschiotti, Patrizia.

J Invest Dermatol ; 137(5): 1042-1050, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28012718

19.

Current perspectives on the immunopathogenesis of systemic sclerosis.

Fuschiotti, Patrizia.

Immunotargets Ther ; 5: 21-35, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27529059

20.

T cells in SSc skin lesions: knowing your enemy.

Fuschiotti, Patrizia.

Nat Rev Rheumatol ; 16(5): 253-254, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-32152550

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Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs.

Genome-wide transcriptome analysis of the STAT6-regulated genes in advanced-stage cutaneous T-cell lymphoma.

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis.

14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in T_C2 and CD8⁺ lymphocytes from patients with scleroderma.

T cells and cytokines in systemic sclerosis.

Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation.

Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis.

The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesis.

Cell Type-Specific Biomarkers of Systemic Sclerosis Disease Severity Capture Cell-Intrinsic and Cell-Extrinsic Circuits.

GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production.

Single-Cell RNA Sequencing Unveils the Clonal and Transcriptional Landscape of Cutaneous T-Cell Lymphomas.

Role of IL-13 in systemic sclerosis.

Dynamic aspects of TCRalpha gene recombination: qualitative and quantitative assessments of the TCRalpha chain repertoire in man and mouse.

Editorial: The underlying pathophysiology and therapeutic approaches for cutaneous T-cell lymphoma.

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors.

Analysis of the TCR alpha-chain rearrangement profile in human T lymphocytes.

Current perspectives on the role of CD8+ T cells in systemic sclerosis.

Skin-Resident Effector Memory CD8⁺CD28^- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.

Current perspectives on the immunopathogenesis of systemic sclerosis.

T cells in SSc skin lesions: knowing your enemy.