Pesquisa | BVS Violência e Saúde

1.

Structural Insights into Yeast Telomerase Recruitment to Telomeres.

Chen, Hongwen; Xue, Jing; Churikov, Dmitri; Hass, Evan P; Shi, Shaohua; Lemon, Laramie D; Luciano, Pierre; Bertuch, Alison A; Zappulla, David C; Géli, Vincent; Wu, Jian; Lei, Ming.

Cell ; 172(1-2): 331-343.e13, 2018 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-29290466

2.

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading.

Delamarre, Axel; Barthe, Antoine; de la Roche Saint-André, Christophe; Luciano, Pierre; Forey, Romain; Padioleau, Ismaël; Skrzypczak, Magdalena; Ginalski, Krzysztof; Géli, Vincent; Pasero, Philippe; Lengronne, Armelle.

Mol Cell ; 77(2): 395-410.e3, 2020 01 16.

Artigo em Inglês | MEDLINE | ID: mdl-31759824

3.

Telomeric C-circles localize at nuclear pore complexes in Saccharomyces cerevisiae.

Aguilera, Paula; Dubarry, Marion; Hardy, Julien; Lisby, Michael; Simon, Marie-Noëlle; Géli, Vincent.

EMBO J ; 41(6): e108736, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35147992

4.

mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.

Lipskaia, Larissa; Breau, Marielle; Cayrou, Christelle; Churikov, Dmitri; Braud, Laura; Jacquet, Juliette; Born, Emmanuelle; Fouillade, Charles; Curras-Alonso, Sandra; Bauwens, Serge; Jourquin, Frederic; Fiore, Frederic; Castellano, Rémy; Josselin, Emmanuelle; Sánchez-Ferrer, Carlota; Giovinazzo, Giovanna; Lachaud, Christophe; Gilson, Eric; Flores, Ignacio; Londono-Vallejo, Arturo; Adnot, Serge; Géli, Vincent.

EMBO Rep ; 25(3): 1650-1684, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38424230

5.

Yra1-bound RNA-DNA hybrids cause orientation-independent transcription-replication collisions and telomere instability.

García-Rubio, María; Aguilera, Paula; Lafuente-Barquero, Juan; Ruiz, José F; Simon, Marie-Noelle; Geli, Vincent; Rondón, Ana G; Aguilera, Andrés.

Genes Dev ; 32(13-14): 965-977, 2018 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-29954833

6.

Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability.

Bonnet, Amandine; Grosso, Ana R; Elkaoutari, Abdessamad; Coleno, Emeline; Presle, Adrien; Sridhara, Sreerama C; Janbon, Guilhem; Géli, Vincent; de Almeida, Sérgio F; Palancade, Benoit.

Mol Cell ; 67(4): 608-621.e6, 2017 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-28757210

7.

Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.

Kermasson, Laëtitia; Churikov, Dmitri; Awad, Aya; Smoom, Riham; Lainey, Elodie; Touzot, Fabien; Audebert-Bellanger, Séverine; Haro, Sophie; Roger, Lauréline; Costa, Emilia; Mouf, Maload; Bottero, Adriana; Oleastro, Matias; Abdo, Chrystelle; de Villartay, Jean-Pierre; Géli, Vincent; Tzfati, Yehuda; Callebaut, Isabelle; Danielian, Silvia; Soares, Gabriela; Kannengiesser, Caroline; Revy, Patrick.

Blood ; 139(16): 2427-2440, 2022 04 21.

Artigo em Inglês | MEDLINE | ID: mdl-35007328

8.

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue.

Sharma, Richa; Sahoo, Sushree S; Honda, Masayoshi; Granger, Sophie L; Goodings, Charnise; Sanchez, Louis; Künstner, Axel; Busch, Hauke; Beier, Fabian; Pruett-Miller, Shondra M; Valentine, Marcus B; Fernandez, Alfonso G; Chang, Ti-Cheng; Géli, Vincent; Churikov, Dmitri; Hirschi, Sandrine; Pastor, Victor B; Boerries, Melanie; Lauten, Melchior; Kelaidi, Charikleia; Cooper, Megan A; Nicholas, Sarah; Rosenfeld, Jill A; Polychronopoulou, Sophia; Kannengiesser, Caroline; Saintomé, Carole; Niemeyer, Charlotte M; Revy, Patrick; Wold, Marc S; Spies, Maria; Erlacher, Miriam; Coulon, Stéphane; Wlodarski, Marcin W.

Blood ; 139(7): 1039-1051, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-34767620

9.

A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells.

Vaurs, Mélina; Audry, Julien; Runge, Kurt W; Géli, Vincent; Coulon, Stéphane.

Nucleic Acids Res ; 50(20): 11682-11695, 2022 11 11.

Artigo em Inglês | MEDLINE | ID: mdl-36330920

10.

Nuclear envelope attachment of telomeres limits TERRA and telomeric rearrangements in quiescent fission yeast cells.

Maestroni, Laetitia; Reyes, Céline; Vaurs, Mélina; Gachet, Yannick; Tournier, Sylvie; Géli, Vincent; Coulon, Stéphane.

Nucleic Acids Res ; 48(6): 3029-3041, 2020 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-31980821

11.

RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends.

Audry, Julien; Maestroni, Laetitia; Delagoutte, Emmanuelle; Gauthier, Tiphaine; Nakamura, Toru M; Gachet, Yannick; Saintomé, Carole; Géli, Vincent; Coulon, Stéphane.

EMBO J ; 34(14): 1942-58, 2015 Jul 14.

Artigo em Inglês | MEDLINE | ID: mdl-26041456

12.

Histone stress: an unexplored source of chromosomal instability in cancer?

Miles, Douglas Maya; Desdouets, Chantal; Géli, Vincent.

Curr Genet ; 65(5): 1081-1088, 2019 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-30976832

13.

How telomeres are replicated.

Gilson, Eric; Géli, Vincent.

Nat Rev Mol Cell Biol ; 8(10): 825-38, 2007 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-17885666

14.

STEEx, a boundary between the world of quiescence and the vegetative cycle.

Maestroni, Laetitia; Géli, Vincent; Coulon, Stéphane.

Curr Genet ; 64(4): 901-905, 2018 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-29392410

15.

CST meets shelterin to keep telomeres in check.

Giraud-Panis, Marie-Josèphe; Teixeira, M Teresa; Géli, Vincent; Gilson, Eric.

Mol Cell ; 39(5): 665-76, 2010 Sep 10.

Artigo em Inglês | MEDLINE | ID: mdl-20832719

16.

Cdc13 and telomerase bind through different mechanisms at the lagging- and leading-strand telomeres.

Faure, Virginie; Coulon, Stéphane; Hardy, Julien; Géli, Vincent.

Mol Cell ; 38(6): 842-52, 2010 Jun 25.

Artigo em Inglês | MEDLINE | ID: mdl-20620955

17.

Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex.

Géli, Vincent; Lisby, Michael.

Bioessays ; 37(12): 1287-92, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26422820

18.

Rad59-facilitated acquisition of Y' elements by short telomeres delays the onset of senescence.

Churikov, Dmitri; Charifi, Ferose; Simon, Marie-Noëlle; Géli, Vincent.

PLoS Genet ; 10(11): e1004736, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25375789

19.

RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts.

Luciano, Pierre; Coulon, Stéphane; Faure, Virginie; Corda, Yves; Bos, Julia; Brill, Steven J; Gilson, Eric; Simon, Marie-Noelle; Géli, Vincent.

EMBO J ; 31(8): 2034-46, 2012 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-22354040

20.

A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells.

Medves, Sandrine; Auchter, Morgan; Chambeau, Laetitia; Gazzo, Sophie; Poncet, Delphine; Grangier, Blandine; Verney, Aurélie; Moussay, Etienne; Ammerlaan, Wim; Brisou, Gabriel; Morjani, Hamid; Géli, Vincent; Palissot, Valérie; Berchem, Guy; Salles, Gilles; Wenner, Thomas.

Br J Haematol ; 174(1): 57-70, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-26970083

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