Detalhe da pesquisa
1.
Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study.
Epilepsia
; 64(1): 139-151, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36196777
2.
Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial.
Epilepsia
; 64(10): 2653-2666, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543865
3.
Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment.
Epilepsy Behav
; 138: 108994, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463826
4.
Fenfluramine significantly reduces day-to-day seizure burden by increasing number of seizure-free days and time between seizures in patients with Dravet syndrome: A time-to-event analysis.
Epilepsia
; 63(1): 130-138, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34676542
5.
Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome.
Epilepsy Behav
; 121(Pt A): 108024, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34023810
6.
Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth.
Epilepsy Behav
; 122: 108212, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34352670
7.
An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies.
Int J Mol Sci
; 22(16)2021 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445144
8.
Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial.
Lancet
; 394(10216): 2243-2254, 2019 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31862249
9.
Cardiovascular safety of fenfluramine in the treatment of Dravet syndrome: Analysis of an ongoing long-term open-label safety extension study.
Epilepsia
; 61(11): 2386-2395, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32809271
10.
Psychosocial impact on siblings of patients with developmental and epileptic encephalopathies.
Epilepsy Behav
; 112: 107377, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32846306
11.
Development and validation of the University of Washington caregiver stress and benefit scales for caregivers of children with or without serious health conditions.
Qual Life Res
; 29(5): 1361-1371, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31902052
12.
A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjectsâ©.
Int J Clin Pharmacol Ther
; 57(1): 11-19, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30336805
13.
A pilot, open-label study of the effectiveness and tolerability of low-dose ZX008 (fenfluramine HCl) in Lennox-Gastaut syndrome.
Epilepsia
; 59(10): 1881-1888, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30146701
14.
Life impact of caregiving for severe childhood epilepsy: Results of expert panels and caregiver focus groups.
Epilepsy Behav
; 74: 135-143, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28734197
15.
The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research.
Epilepsy Behav
; 70(Pt A): 104-109, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28431364
16.
An Analysis of Rescue Medication Utilization from a 3-Month, Randomized, Double-Blind, Placebo-Controlled Study in Patients with Chronic Low Back Pain Treated with Single-Entity, Twice-Daily, Extended-Release Hydrocodone.
Pain Med
; 16(12): 2338-43, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26301791
17.
Predicting Response to Subacromial Injections and Lidocaine/Tetracaine Patch from Pretreatment Pain Quality in Patients with Shoulder Impingement Syndrome.
Pain Med
; 16(7): 1333-40, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25917860
18.
Predicting response to pregabalin from pretreatment pain quality: clinical applications of the pain quality assessment scale.
Pain Med
; 14(4): 526-32, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22759088
19.
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life.
Mitochondrion
; 68: 1-9, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36374792
20.
Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective.
Epilepsy Res
; 185: 106976, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35843016