RESUMO
Diabetic foot ulcers occur as a common complication of diabetes. The concomitant infection significantly delays the healing of the ulcers. Antibiotic treatment of infected ulcers is complicated by the formation of microbial biofilms, which are often heterogeneous and resistant to antibiotics. Bacteriophage therapy is considered an additional approach to the treatment of infected wounds. Here, we describe the basic method of application of bacteriophages for the treatment of infected diabetic foot ulcers, including very large ones.
Assuntos
Bacteriófagos , Diabetes Mellitus , Pé Diabético , Infecção dos Ferimentos , Humanos , Pé Diabético/terapia , Pé Diabético/complicações , Antibacterianos/uso terapêutico , Infecção dos Ferimentos/terapia , Cicatrização , Diabetes Mellitus/tratamento farmacológicoRESUMO
Diabetic foot ulcers occur as a common complication of diabetes. Healing of the ulcers is largely delayed by the concomitant infection. Antibiotic treatment of infected ulcers is complicated by formation of microbial biofilms , which are often heterogeneous and resistant to antibiotics. Bacteriophage therapy is considered as an additional approach to the treatment of infected wounds. Here, we describe the basic method of application of bacteriophages for treatment of infected diabetic foot ulcers, including ones that are very large.