[A family history of vitiligo with autosomal dominant inheritance].

A family history of vitiligo was reported in this paper,and the reason causing disease was discussed. We think that the vitiligo in the family history is caused by autosomal dominant inheritance.

[Detection of Y chromosome in human and Microtus mandarinus with FISH].

The purpose of the investigation was to detect the Y chromosome of human and Microtus mandarinus with the satellite DNA probe in human's Yq by fluorescence in situ hybridization(FISH). We hybridizied the probe with the metaphase chromosome and interphase nucleus specimens of humanbeing and Microtus mandarinus respectively. The results showed that there was hybridization signal on metaphase chromosome and interphase nucleus of human, but no signal on metaphase chromosome and interphase nucleus of Microtus mandarinus. According to the results,we discussed the homologue between pY3.4 in Y chromosome of humanbeing and DNA of Microtus mandarinus and FISH result of Microtus mandarinus.

Misdiagnosis of left supraclavicular lymph node metastasis of hepatocellular carcinoma: a case report.

Left supraclavicular lymph node metastasis is a rare presentation of hepatocellular carcinoma (HCC). This phenomenon is easily neglected in the clinic. A 56-year-old man presented with HCC. On examination, a 1cm long left supraclavicular lymph node was palpated. Auxiliary examination indicated a lesion located in the right lobe of the liver. Fine needle aspiration cytology (FNAC) of the enlarged lymph node was performed; however, only necrosis was found. Hepatectomy was performed and HCC was confirmed by Hematoxylin-Eosin staining. However, 14 d after surgery, significantly enlarged left supraclavicular lymph nodes, a new intrahepatic lesion, and pulmonary and mediastinal metastasis appeared. An excisional biopsy of the left supraclavicular lymph node was performed, and its findings confirmed metastatic HCC. The patient's HCC rapidly progressed and he died one month later. It is possible for HCC to metastasize to the left supraclavicular lymph node. Surgeons should always consider an overall physical examination. When left supraclavicular lymphadenopathy of unknown origin is encountered, FNAC should be performed initially. If the results are negative, an excisional biopsy and subsequent Positron emission tomography - computed tomography scanning should be performed. These are very important for making the correct diagnosis and for selecting reasonable therapies.