The Anxiety Depression Distress Inventory-27 (ADDI-27): New Evidence of Factor Structure, Item-Level Measurement Invariance, and Validity.

Three studies examining the factor structure and psychometric properties of the Anxiety Depression Distress Inventory-27 (ADDI-27) extended the initial instrument development studies for this recently introduced inventory. The ADDI-27 is an empirically derived short form of the Mood and Anxiety Questionaire-90 (MASQ-90) comprising three scales: Positive Affect, Somatic Anxiety, and General Distress. The main objectives of Study 1 (N = 700) were to examine the factor structure of the ADDI-27 and its measurement invariance across gender at the item level. The objective of Study 2 (N = 538) was to examine evidence for the convergent and discriminant validity of scores on the ADDI-27. The objective of Study 3 (N = 240) was to assess further evidence for the nomological network and convergent and discriminant validity of the ADDI-27 scores. Results of exploratory structural equation modeling yielded strong support for a 3-factor model, with approximate fit indexes meeting or exceeding the conventional cutoffs. With p ≤ .001 as the criterion for detecting noninvariance, results of measurement invariance analysis suggested that all of the ADDI-27 items were invariant across gender. Results of multivariate validity analyses across 2 studies provided support for the convergent and discriminant validity of scores on the ADDI-27 scales.

The Cortisol Awakening Response Mediates the Relationship Between Acculturative Stress and Self-Reported Health in Mexican Americans.

BACKGROUND: The assessment of acculturative stress as synonymous with acculturation level overlooks the dynamic, interactive, and developmental nature of the acculturation process. An individual's unique perception and response to a range of stressors at each stage of the dynamic process of acculturation may be associated with stress-induced alterations in important biological response systems that mediate health outcomes. Evidence suggests the cortisol awakening response (CAR) is a promising pre-clinical biomarker of stress exposure that may link acculturative stress to self-reported health in Mexican Americans. PURPOSE: The aim of the current study was to examine whether alterations in the CAR mediate the relationship between acculturative stress and self-reported health in Mexican Americans. METHODS: Salivary cortisol samples were collected at awakening, 30, 45, and 60 min thereafter, on two consecutive weekdays from a sample of adult Mexican Americans. Acculturative stress and self-reported health were assessed. Data were aggregated and analyzed (n = 89) using a mixed effects regression model and path analysis. RESULTS: Poorer self-reported health was associated with attenuated CAR profiles (primarily due to a diminished post-awakening rise in cortisol) predicted by both moderate and high levels of exposure to acculturative stress. Stress-induced alterations in the CAR mediated the relationship between exposure to acculturative stressors and self-reported health. CONCLUSIONS: Findings demonstrate that different levels of acculturative stress are associated with distinct CAR profiles and suggest the CAR is one possible biological pathway through which exposure to culturally unique stressors may be linked to health disparities.

Factor structure, factorial invariance, and validity of the Multidimensional Shame-Related Response Inventory-21 (MSRI-21).

We describe 2 studies designed to evaluate scores on the Multidimensional Shame-related Response Inventory-21 (MSRI-21), a recently developed instrument that measures affective and behavioral responses to shame. The inventory assesses shame-related responses in 3 categories: negative self-evaluation, fear of social consequences, and maladaptive behavior tendency. For Study 1, (N = 743) undergraduates completed the MSRI-21. Confirmatory factor analysis supported the validity of the MSRI-21 3-factor structure. Latent variable modeling of coefficient-α provided strong evidence for the internal consistency of scores on each scale. In Study 2, (N = 540) undergraduates completed the instrument along with 5 concurrent measures chosen for clinical significance. Achievement of factorial invariance supported the use of MSRI-21 scale scores to make valid mean comparisons across gender. In addition, MSRI-21 scale scores were associated as expected with scores on measures of self-harm, suicide, and other risk factors. Taken together, results of 2 studies support the internal consistency reliability, factorial validity, factorial invariance, and convergent validity of scores on the MSRI-21. Further work is needed to assess the temporal stability of the MSRI-21 scale scores, invariance across clinical status and other groupings, item-level measurement properties, and viability in highly symptomatic samples. (PsycINFO Database Record

The Social Anxiety and Depression Life Interference-24 Inventory: Classical and modern psychometric evaluations.

Two instrument validation studies broadened the research literature exploring the factor structure, internal consistency reliability, and concurrent validity of scores on the Social Anxiety and Depression Life Interference-24 Inventory (SADLI-24; Osman, Bagge, Freedenthal, Guiterrez, & Emmerich, 2011). Study 1 (N = 1065) was undertaken to concurrently appraise three competing factor models for the instrument: a unidimensional model, a two-factor oblique model and a bifactor model. The bifactor model provided the best fit to the study sample data. Study 2 (N = 220) extended the results from Study 1 with an investigation of the convergent and discriminant validity for the bifactor model of the SADLI-24 with multiple regression analyses and scale-level exploratory structural equation modeling. This project yields data that augments the initial instrument development investigations for the target measure.

Experimental demonstration of weak-light laser ranging and data communication for LISA.

Interferometric gravitational wave detectors with an unequal and time-varying arm length configuration like the Laser Interferometer Space Antenna rely on time-delay interferometry (TDI) for laser frequency noise subtraction. However, the TDI algorithm requires a laser ranging scheme with meter accuracy over a five million kilometer arm length. At the end of each arm only about 100 pW of light power will be detected for gravitational wave measurements and only 1% of this power can be used for laser ranging in order to avoid degradation in the phase stability of the science measurements. Here, we present the first experimental demonstration of such a ranging scheme at 1 pW power levels using a Direct Sequence Spread Spectrum (DS/SS) modulation. This type of modulation also enables optical communication by encoding data with ranging signals and provides significant noise reduction against spurious interfering signals for bidirectional ranging. Experimental results show ranging measurements of 42 cm at 3 Hz and the viability of highly reliable data transfer at several kilobits per second.

Using a Recently Developed Self-Report Instrument to Assess Social Anxiety Life Interference in Individuals with Co-occurring Depression: A Known-Groups Analysis.

Social anxiety is a common condition that often entails substantial adverse impacts on social, educational, and occupational functioning. Moreover, social anxiety often co-occurs with depression, making it difficult to distinguish the unique effects of each condition, which can pose a challenge to effective treatment planning and intervention. Until recently, clinicians have not had access to a validated psychometric instrument that measures the degree of life interference stemming from social anxiety, and that distinguishes life interference associated with social anxiety from that associated with depression. Fortunately, recent work has yielded a novel instrument that combines a measure of social anxiety life interference with a measure of depression life interference, providing a measure that can identify functional disruptions uniquely associated with social anxiety, and that may occur in the presence of comorbid depression. The present article reviews two studies describing the development and psychometric properties of the Social Anxiety and Depression Life Interference Inventory (SADLI-24) and adds to the existing literature by demonstrating the discriminative accuracy of the inventory using a "known-groups" methodology. The article concludes by providing recommendations for the practical application of the SADLI-24 and suggesting future directions for research with the instrument.

Interaction of tocopherols and phenolic compounds with membrane lipid components: evaluation of their antioxidant activity in a liposomal model system.

This paper describes the use of complex liposomes as real membrane models to evaluate the potential benefits of several antioxidants in relation to lipid peroxidation. The xanthine oxidase/Fe(3+)-ADP-EDTA and the Fe(2+)/H2O2 systems have been used to generate hydroxyl radicals and the water soluble azo-compound 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) to generate carbon centered radicals (A*) by thermal decomposition. The antioxidant behavior of the rosemary and citrus plant extracts and vitamin-E and vitamin-E acetate alpha-tocopherols have been analyzed. The order of effectiveness in avoiding radical chain reactions has been established by using the colorimetric thiobarbituric acid reaction and the fluorescent probe DPH-PA. ESR spectroscopy has been used to carry out the pursuit of the oxidation processes on the basis of the identification of the radical species resulting from the oxidant system and the ability of the antioxidants to act as scavengers for hydroxyl and AAPH-derived radicals. The modification of the main transition temperature for the lipid mixture and the splitting of the calorimetric peak in the presence of the antioxidants were demonstrated by differential scanning calorimetry. The results obtained showed that the phenols-containing plant extracts and alpha-tocopherols perturb the phase behavior of the BBE lipid bilayer and have a fluidifying effect that could favor the known antioxidant capability and scavenging characteristics of these compounds. 31P-NMR results could be interpreted as, after the incorporation of these antioxidants, those lipid molecules interacting with antioxidants give rise to lamellar phase spectral components with resonance position at lower fields or to isotropic signals in accordance with a higher motion of their phosphate groups.