Detalhe da pesquisa
1.
Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer.
Cancer Immunol Immunother
; 73(3): 57, 2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367056
2.
Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity.
Biochem J
; 480(17): 1411-1427, 2023 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37622331
3.
Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4).
Clin Exp Immunol
; 211(3): 239-247, 2023 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36655514
4.
Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET.
Bioorg Med Chem Lett
; 89: 129310, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37137430
5.
Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury.
Brain
; 144(12): 3788-3807, 2021 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34972207
6.
Mode of action and toxicological effects of the sesquiterpenoid, nootkatone, in insects.
Pestic Biochem Physiol
; 183: 105085, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35430075
7.
The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase.
Molecules
; 27(23)2022 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500407
8.
Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG.
Am J Physiol Cell Physiol
; 320(4): C577-C590, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33439777
9.
A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2).
J Biol Chem
; 295(11): 3563-3575, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024694
10.
The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke.
Pharm Res
; 38(5): 803-817, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33982226
11.
Development of an a priori computational approach for brain uptake of compounds in an insect model system.
Bioorg Med Chem Lett
; 40: 127930, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33711441
12.
Dual monoamine oxidase B and acetylcholine esterase inhibitors for treating movement and cognition deficits in a C. elegans model of Parkinson's disease.
Med Chem Res
; 30(5): 1166-1174, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34744409
13.
Synthesis of Illudinine from Dimedone and Identification of Activity as a Monoamine Oxidase Inhibitor.
J Org Chem
; 85(21): 13429-13437, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32830978
14.
Pyrvinium Pamoate Use in a B cell Acute Lymphoblastic Leukemia Model of the Bone Tumor Microenvironment.
Pharm Res
; 37(3): 43, 2020 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31989336
15.
Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.
J Biol Chem
; 293(11): 4134-4148, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378847
16.
The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia.
J Pharmacol Exp Ther
; 370(1): 25-34, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010844
17.
4-Hydroxynonenal and 4-Oxononenal Differentially Bind to the Redox Sensor MitoNEET.
Chem Res Toxicol
; 32(6): 977-981, 2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117349
18.
Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1.
Bioorg Med Chem Lett
; 29(7): 901-904, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770154
19.
Inhibition of the FAD containing ER oxidoreductin 1 (Ero1) protein by EN-460 as a strategy for treatment of multiple myeloma.
Bioorg Med Chem
; 27(8): 1479-1488, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850265
20.
Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia.
Bioorg Med Chem Lett
; 28(10): 1937-1942, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650292