Pesquisa | BVS Violência e Saúde

1.

Elliott Dan Kieff, MD, PhD (1943-2024).

Raab-Traub, Nancy; Gewurz, Benjamin E.

Cell ; 187(8): 1819-1821, 2024 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-38608648

2.

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.

Yiu, Stephanie Pei Tung; Zerbe, Cassie; Vanderwall, David; Huttlin, Edward L; Weekes, Michael P; Gewurz, Benjamin E.

Mol Cell ; 83(13): 2367-2386.e15, 2023 Jul 06.

Artigo em Inglês | MEDLINE | ID: mdl-37311461

3.

MYC Controls the Epstein-Barr Virus Lytic Switch.

Guo, Rui; Jiang, Chang; Zhang, Yuchen; Govande, Apurva; Trudeau, Stephen J; Chen, Fang; Fry, Christopher J; Puri, Rishi; Wolinsky, Emma; Schineller, Molly; Frost, Thomas C; Gebre, Makda; Zhao, Bo; Giulino-Roth, Lisa; Doench, John G; Teng, Mingxiang; Gewurz, Benjamin E.

Mol Cell ; 78(4): 653-669.e8, 2020 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-32315601

4.

Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression.

Liao, Yifei; Yan, Jinjie; Beri, Nina R; Giulino-Roth, Lisa; Cesarman, Ethel; Gewurz, Benjamin E.

PLoS Pathog ; 20(4): e1011939, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38683861

5.

Epstein-Barr virus latency programs dynamically sensitize B cells to ferroptosis.

Burton, Eric M; Voyer, Jewel; Gewurz, Benjamin E.

Proc Natl Acad Sci U S A ; 119(11): e2118300119, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35275790

6.

Correction: Epstein-Barr virus oncoprotein-driven B cell metabolism remodeling.

Burton, Eric M; Gewurz, Benjamin E.

PLoS Pathog ; 18(10): e1010920, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-36264852

7.

The nuclear lamina binds the EBV genome during latency and regulates viral gene expression.

Caruso, Lisa Beatrice; Guo, Rui; Keith, Kelsey; Madzo, Jozef; Maestri, Davide; Boyle, Sarah; Wasserman, Jason; Kossenkov, Andrew; Gewurz, Benjamin E; Tempera, Italo.

PLoS Pathog ; 18(4): e1010400, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35421198

8.

CYB561A3 is the key lysosomal iron reductase required for Burkitt B-cell growth and survival.

Wang, Zhonghao; Guo, Rui; Trudeau, Stephen J; Wolinsky, Emma; Ast, Tslil; Liang, Jin Hua; Jiang, Chang; Ma, Yijie; Teng, Mingxiang; Mootha, Vamsi K; Gewurz, Benjamin E.

Blood ; 138(22): 2216-2230, 2021 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-34232987

9.

N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay.

Xia, Tian-Liang; Li, Xingyang; Wang, Xueping; Zhu, Yun-Jia; Zhang, Hua; Cheng, Weisheng; Chen, Mei-Ling; Ye, Ying; Li, Yan; Zhang, Ao; Dai, Dan-Ling; Zhu, Qian-Ying; Yuan, Li; Zheng, Jian; Huang, Huilin; Chen, Si-Qi; Xiao, Zhi-Wen; Wang, Hong-Bo; Roy, Gaurab; Zhong, Qian; Lin, Dongxin; Zeng, Yi-Xin; Wang, Jinkai; Zhao, Bo; Gewurz, Benjamin E; Chen, Jianjun; Zuo, Zhixiang; Zeng, Mu-Sheng.

EMBO Rep ; 22(4): e50128, 2021 04 07.

Artigo em Inglês | MEDLINE | ID: mdl-33605073

10.

Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.

Dalton, Tanner; Doubrovina, Ekaterina; Pankov, Dmitry; Reynolds, Raymond; Scholze, Hanna; Selvakumar, Annamalai; Vizconde, Teresa; Savalia, Bhumesh; Dyomin, Vadim; Weigel, Christoph; Oakes, Christopher C; Alonso, Alicia; Elemento, Olivier; Pan, Heng; Phillip, Jude M; O'Reilly, Richard J; Gewurz, Benjamin E; Cesarman, Ethel; Giulino-Roth, Lisa.

Blood ; 135(21): 1870-1881, 2020 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-32157281

11.

CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells.

Smith, Nicholas A; Coleman, Carrie B; Gewurz, Benjamin E; Rochford, Rosemary.

J Virol ; 94(11)2020 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-32238579

12.

Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival.

Wang, Liang Wei; Wang, Zhonghao; Ersing, Ina; Nobre, Luis; Guo, Rui; Jiang, Sizun; Trudeau, Stephen; Zhao, Bo; Weekes, Michael P; Gewurz, Benjamin E.

PLoS Pathog ; 15(9): e1008030, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31518366

13.

EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein-Barr virus-associated gastric cancer.

Soldan, Samantha S; Anderson, Emma M; Frase, Drew M; Zhang, Yue; Caruso, Lisa B; Wang, Yin; Deakyne, Julianna S; Gewurz, Benjamin E; Tempera, Italo; Lieberman, Paul M; Messick, Troy E.

Gastric Cancer ; 24(5): 1076-1088, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-33929613

14.

Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma.

Wang, Chong; Jiang, Sizun; Ke, Liangru; Zhang, Luyao; Li, Difei; Liang, Jun; Narita, Yohei; Hou, Isabella; Chen, Chen-Hao; Wang, Liangwei; Zhong, Qian; Ling, Yihong; Lv, Xing; Xiang, Yanqun; Guo, Xiang; Teng, Mingxiang; Tsao, Sai-Wah; Gewurz, Benjamin E; Zeng, Mu-Sheng; Zhao, Bo.

J Biol Chem ; 294(25): 9734-9745, 2019 06 21.

Artigo em Inglês | MEDLINE | ID: mdl-31073033

15.

RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B Lymphocytes.

Wang, Chong; Li, Difei; Zhang, Luyao; Jiang, Sizun; Liang, Jun; Narita, Yohei; Hou, Isabella; Zhong, Qian; Zheng, Zeguang; Xiao, Haipeng; Gewurz, Benjamin E; Teng, Mingxiang; Zhao, Bo.

J Virol ; 93(13)2019 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-31019051

16.

TAF Family Proteins and MEF2C Are Essential for Epstein-Barr Virus Super-Enhancer Activity.

Wang, Chong; Jiang, Sizun; Zhang, Luyao; Li, Difei; Liang, Jun; Narita, Yohei; Hou, Isabella; Zhong, Qian; Gewurz, Benjamin E; Teng, Mingxiang; Zhao, Bo.

J Virol ; 93(16)2019 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-31167905

17.

Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.

Minamitani, Takeharu; Ma, Yijie; Zhou, Hufeng; Kida, Hiroshi; Tsai, Chao-Yuan; Obana, Masanori; Okuzaki, Daisuke; Fujio, Yasushi; Kumanogoh, Atsushi; Zhao, Bo; Kikutani, Hitoshi; Kieff, Elliott; Gewurz, Benjamin E; Yasui, Teruhito.

Proc Natl Acad Sci U S A ; 114(18): 4751-4756, 2017 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-28351978

18.

Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300.

Wang, Chong; Zhou, Hufeng; Xue, Yong; Liang, Jun; Narita, Yohei; Gerdt, Catherine; Zheng, Amy Y; Jiang, Runsheng; Trudeau, Stephen; Peng, Chih-Wen; Gewurz, Benjamin E; Zhao, Bo.

J Virol ; 92(9)2018 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-29467311

19.

Epstein-Barr virus oncoprotein-driven B cell metabolism remodeling.

Burton, Eric M; Gewurz, Benjamin E.

PLoS Pathog ; 18(2): e1010254, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35108325

20.

Epstein-Barr Virus LMP1-Mediated Oncogenicity.

Wang, Liang Wei; Jiang, Sizun; Gewurz, Benjamin E.

J Virol ; 91(21)2017 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-28835489

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