Detalhe da pesquisa
1.
Mitochondrial DNA heteroplasmy distinguishes disease manifestation in PINK1/PRKN-linked Parkinson's disease.
Brain
; 146(7): 2753-2765, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36478228
2.
Comparison of two protocols for the generation of iPSC-derived human astrocytes.
Biol Proced Online
; 25(1): 26, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37730545
3.
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Brain
; 145(3): 964-978, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919646
4.
Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation.
Mov Disord
; 37(7): 1405-1415, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460111
5.
Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism.
Brain
; 143(10): 3041-3051, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33029617
6.
Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression.
J Biol Chem
; 291(8): 3932-46, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26679997
7.
The mouse brain metabolome: region-specific signatures and response to excitotoxic neuronal injury.
Am J Pathol
; 185(6): 1699-712, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934215
8.
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Proc Natl Acad Sci U S A
; 110(19): 7820-5, 2013 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23610393
9.
Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers.
Ann Neurol
; 86(2): 324-326, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31148195
10.
Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells.
Biomedicines
; 11(10)2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37893215
11.
Mitochondrial Mechanisms of LRRK2 G2019S Penetrance.
Front Neurol
; 11: 881, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32982917
12.
Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy.
Sci Rep
; 10(1): 16736, 2020 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33028849
13.
Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease.
Antioxid Redox Signal
; 31(16): 1213-1234, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31303019
14.
5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.
Neoplasia
; 16(6): 511-28, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24970385
15.
Simultaneous extraction of proteins and metabolites from cells in culture.
MethodsX
; 1: 74-80, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-26150938
16.
Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines.
Biochem Pharmacol
; 81(11): 1329-42, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21453686
17.
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy.
Biochem Pharmacol
; 81(3): 364-78, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044612
18.
COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells.
Biochem Pharmacol
; 82(10): 1277-90, 2011 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21745461
19.
UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells.
Biochem Pharmacol
; 81(1): 13-23, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20849830