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1.
Dokl Biochem Biophys ; 485(1): 129-131, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31201632

RESUMO

This is the first study to isolate the taxoid taxuyunnanin C (group of 14-hydroxylated taxoids) from the biomass of suspension cell culture of the Canadian yew (Taxus canadensis). According to available data, this is the first report of the presence of nonpolar (polyacylated) forms of 14-hydroxylated taxoids, including taxuyunnanin C, in T. canadensis.


Assuntos
Células Vegetais/metabolismo , Taxoides/metabolismo , Taxus/metabolismo , Taxoides/análise , Taxus/citologia
2.
Dokl Biochem Biophys ; 476(1): 337-339, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29101752

RESUMO

This is the first study to show that the formation of 14ß-hydroxylated derivatives of taxa-4(20),11-diene is a specific feature of in vitro cultured dedifferentiated yew cells that distinguishes them from intact plant cells. This may be due to a lower toxicity of the 14-OH taxoids for proliferating plant cells compared to the 13-OH derivatives.


Assuntos
Taxoides/metabolismo , Taxus/metabolismo , Células Cultivadas , Hidroxilação , Taxus/citologia
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