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1.
J Am Acad Dermatol ; 83(6): 1717-1723, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32112995

RESUMO

Lichen planus is a benign inflammatory disorder of unknown etiology that may affect the skin, mucosae, scalp, and nails. When the nails are affected, it may lead to permanent destruction with severe functional and psychosocial consequences. Therefore, prompt diagnosis and early treatment are essential, even in mild cases. There are currently no guidelines for the management of nail lichen planus and the published literature on treatment is limited. The aim of this review is to provide practical management recommendations for the classical form of nail lichen planus, especially when restricted to the nails. Topical treatment has poor short-term efficacy and may cause long-term side effects. Instead, intralesional and intramuscular triamcinolone acetonide should be considered first-line therapies. Oral retinoids are second-line choices, and immunosuppressive agents may also be considered.


Assuntos
Consenso , Líquen Plano/tratamento farmacológico , Doenças da Unha/tratamento farmacológico , Guias de Prática Clínica como Assunto , Triancinolona Acetonida/administração & dosagem , Administração Oral , Dermatologia/métodos , Dermatologia/normas , Glucocorticoides/administração & dosagem , Humanos , Imunossupressores/administração & dosagem , Injeções Intralesionais , Injeções Intramusculares , Líquen Plano/diagnóstico , Líquen Plano/imunologia , Líquen Plano/psicologia , Doenças da Unha/diagnóstico , Doenças da Unha/imunologia , Doenças da Unha/psicologia , Unhas/efeitos dos fármacos , Unhas/imunologia , Unhas/patologia , Retinoides/administração & dosagem , Resultado do Tratamento
4.
Skin Appendage Disord ; 6(5): 287-295, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33088814

RESUMO

BACKGROUND: Blue nevus of the nail apparatus is a rare entity and only isolated cases are reported in the literature. OBJECTIVE: The aim of this study was to better characterize blue nevus at the nail unit. METHODS: Retrospective analysis of all nail unit blue nevi from the Nail Group of the French Society of Dermatology was compared to the literature. RESULTS: Eleven cases were retrieved from 2002 to 2019 with an average age of 45 years. The majority were women (9/11) and acquired (10/11). Hands were more frequently involved (9/11) with a predilection for the thumb and 2 cases were located on the hallux. Nail unit blue nevus mostly presented as a well-delimited blue spot of the lunula (9/11) and histologically was of the common type (10/11). There was no malignancy. CONCLUSION: Nail unit blue nevus is a rare asymptomatic benign entity, mostly acquired on the thumb or the hallux of women. The most frequent presentation is a painless blue spot on the lunula. Congenital blue nevi seem to only affect the paronychium. Main differential diagnosis is melanoma and histopathological examination is mandatory.

6.
Presse Med ; 43(11): 1267-78, 2014 Nov.
Artigo em Francês | MEDLINE | ID: mdl-25451634

RESUMO

Nail diseases are varied, and their diagnosis is often difficult. Misdiagnosis can result in failure to recognize a severe disease in urgent need of treatment and in the prescription of treatments that are inappropriate, long, ineffective, and expensive. Acute paronychia must be managed rapidly, treated with antiseptics several times a day, and closely monitored. Nail lichen must be recognized early and treated rapidly and appropriately to prevent permanent scarring. All chronic pain (to shocks or cold) of the tip of a finger or toe should suggest a glomus tumor. Any unexplained persistent single-finger onychopathy should in principle cause the physician to suspect a tumor, carcinoma, or melanoma and to order a histologic examination. An onychopathy must not be treated as an onychomycosis without diagnostic certainty. Repeated microtraumas of the toenails cause injuries that absolutely must be differentiated from onychomycosis. In growth of the big toenail can often be avoided by appropriate cutting of the nails, leaving in place the lateral parts of the nail plate.


Assuntos
Doenças da Unha/diagnóstico , Doenças da Unha/etiologia , Unhas/patologia , Diagnóstico Diferencial , Diagnóstico por Imagem , Dissecação , Humanos , Doenças da Unha/terapia , Unhas/cirurgia , Neoplasias Cutâneas/diagnóstico
8.
Radiology ; 223(1): 143-51, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11930059

RESUMO

PURPOSE: To determine the magnetic resonance (MR) imaging findings in recurrent glomus tumors of the fingertips. MATERIALS AND METHODS: Twenty-four consecutive patients with recurrent pain after previous excision of a glomus tumor of the fingertip underwent MR imaging studies and surgery. T1-weighted spin-echo MR images were obtained in each patient before and after intravenous injection of contrast material; T2-weighted spin-echo and three-dimensional gradient-recalled echo images were also obtained. MR angiography was performed in four patients. Postsurgical histopathologic analysis revealed recurrent glomus tumors in 22 patients. Signal intensity, enhancement, and margins of the scar tissue and the recurrent tumors at MR were assessed. RESULTS: The postsurgical scars were depicted in 21 (88%) of 24 patients with all sequences but were best demonstrated on gradient-recalled echo MR images. Seven patients had undergone multiple surgical procedures and had extensive scar tissue and, in one case, a neuroma. In all patients, MR imaging revealed a nodule compatible with the diagnosis of a recurrent glomus tumor. In 13 (54%) of 24 patients, the nodule had typical features of a glomus tumor. In eight (33%) of 24 patients, the tumors had low signal intensity or isointensity compared with the nail bed on T2-weighted images. In six (25%) of 24 patients, the tumors had faint enhancement after intravenous gadolinium chelate administration. The margins of the tumors were blurred by scar tissue in nine of 24 cases. CONCLUSION: MR imaging can aid in the evaluation of recurrent glomus tumors.


Assuntos
Dedos/patologia , Tumor Glômico/patologia , Imageamento por Ressonância Magnética , Recidiva Local de Neoplasia/patologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
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