Pesquisa | BVS Violência e Saúde

1.

Integrative spatial analysis reveals a multi-layered organization of glioblastoma.

Greenwald, Alissa C; Darnell, Noam Galili; Hoefflin, Rouven; Simkin, Dor; Mount, Christopher W; Gonzalez Castro, L Nicolas; Harnik, Yotam; Dumont, Sydney; Hirsch, Dana; Nomura, Masashi; Talpir, Tom; Kedmi, Merav; Goliand, Inna; Medici, Gioele; Laffy, Julie; Li, Baoguo; Mangena, Vamsi; Keren-Shaul, Hadas; Weller, Michael; Addadi, Yoseph; Neidert, Marian C; Suvà, Mario L; Tirosh, Itay.

Cell ; 187(10): 2485-2501.e26, 2024 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-38653236

2.

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.

Mathewson, Nathan D; Ashenberg, Orr; Tirosh, Itay; Gritsch, Simon; Perez, Elizabeth M; Marx, Sascha; Jerby-Arnon, Livnat; Chanoch-Myers, Rony; Hara, Toshiro; Richman, Alyssa R; Ito, Yoshinaga; Pyrdol, Jason; Friedrich, Mirco; Schumann, Kathrin; Poitras, Michael J; Gokhale, Prafulla C; Gonzalez Castro, L Nicolas; Shore, Marni E; Hebert, Christine M; Shaw, Brian; Cahill, Heather L; Drummond, Matthew; Zhang, Wubing; Olawoyin, Olamide; Wakimoto, Hiroaki; Rozenblatt-Rosen, Orit; Brastianos, Priscilla K; Liu, X Shirley; Jones, Pamela S; Cahill, Daniel P; Frosch, Matthew P; Louis, David N; Freeman, Gordon J; Ligon, Keith L; Marson, Alexander; Chiocca, E Antonio; Reardon, David A; Regev, Aviv; Suvà, Mario L; Wucherpfennig, Kai W.

Cell ; 184(5): 1281-1298.e26, 2021 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-33592174

3.

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Neftel, Cyril; Laffy, Julie; Filbin, Mariella G; Hara, Toshiro; Shore, Marni E; Rahme, Gilbert J; Richman, Alyssa R; Silverbush, Dana; Shaw, McKenzie L; Hebert, Christine M; Dewitt, John; Gritsch, Simon; Perez, Elizabeth M; Gonzalez Castro, L Nicolas; Lan, Xiaoyang; Druck, Nicholas; Rodman, Christopher; Dionne, Danielle; Kaplan, Alexander; Bertalan, Mia S; Small, Julia; Pelton, Kristine; Becker, Sarah; Bonal, Dennis; Nguyen, Quang-De; Servis, Rachel L; Fung, Jeremy M; Mylvaganam, Ravindra; Mayr, Lisa; Gojo, Johannes; Haberler, Christine; Geyeregger, Rene; Czech, Thomas; Slavc, Irene; Nahed, Brian V; Curry, William T; Carter, Bob S; Wakimoto, Hiroaki; Brastianos, Priscilla K; Batchelor, Tracy T; Stemmer-Rachamimov, Anat; Martinez-Lage, Maria; Frosch, Matthew P; Stamenkovic, Ivan; Riggi, Nicolo; Rheinbay, Esther; Monje, Michelle; Rozenblatt-Rosen, Orit; Cahill, Daniel P; Patel, Anoop P.

Cell ; 178(4): 835-849.e21, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31327527

4.

Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours.

Gavish, Avishai; Tyler, Michael; Greenwald, Alissa C; Hoefflin, Rouven; Simkin, Dor; Tschernichovsky, Roi; Galili Darnell, Noam; Somech, Einav; Barbolin, Chaya; Antman, Tomer; Kovarsky, Daniel; Barrett, Thomas; Gonzalez Castro, L Nicolas; Halder, Debdatta; Chanoch-Myers, Rony; Laffy, Julie; Mints, Michael; Wider, Adi; Tal, Rotem; Spitzer, Avishay; Hara, Toshiro; Raitses-Gurevich, Maria; Stossel, Chani; Golan, Talia; Tirosh, Amit; Suvà, Mario L; Puram, Sidharth V; Tirosh, Itay.

Nature ; 618(7965): 598-606, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37258682

5.

Clinical trial links oncolytic immunoactivation to survival in glioblastoma.

Ling, Alexander L; Solomon, Isaac H; Landivar, Ana Montalvo; Nakashima, Hiroshi; Woods, Jared K; Santos, Andres; Masud, Nafisa; Fell, Geoffrey; Mo, Xiaokui; Yilmaz, Ayse S; Grant, James; Zhang, Abigail; Bernstock, Joshua D; Torio, Erickson; Ito, Hirotaka; Liu, Junfeng; Shono, Naoyuki; Nowicki, Michal O; Triggs, Daniel; Halloran, Patrick; Piranlioglu, Raziye; Soni, Himanshu; Stopa, Brittany; Bi, Wenya Linda; Peruzzi, Pierpaolo; Chen, Ethan; Malinowski, Seth W; Prabhu, Michael C; Zeng, Yu; Carlisle, Anne; Rodig, Scott J; Wen, Patrick Y; Lee, Eudocia Quant; Nayak, Lakshmi; Chukwueke, Ugonma; Gonzalez Castro, L Nicolas; Dumont, Sydney D; Batchelor, Tracy; Kittelberger, Kara; Tikhonova, Ekaterina; Miheecheva, Natalia; Tabakov, Dmitry; Shin, Nara; Gorbacheva, Alisa; Shumskiy, Artemy; Frenkel, Felix; Aguilar-Cordova, Estuardo; Aguilar, Laura K; Krisky, David; Wechuck, James.

Nature ; 623(7985): 157-166, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37853118

6.

Diagnostic, therapeutic, and prognostic implications of the 2021 World Health Organization classification of tumors of the central nervous system.

Gritsch, Simon; Batchelor, Tracy T; Gonzalez Castro, L Nicolas.

Cancer ; 128(1): 47-58, 2022 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-34633681

7.

Relevant pharmacologic interactions in the concurrent management of brain tumor-related epilepsy and venous thromboembolism: a systematic review.

Gritsch, David; Gonzalez Castro, L Nicolas.

J Neurooncol ; 157(2): 285-296, 2022 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-35312937

8.

A practical guide to neuro-oncology fellowship.

Gonzalez Castro, L Nicolas; Forst, Deborah A; Plotkin, Scott R; Lee, Eudocia Q.

J Neurooncol ; 156(1): 73-79, 2022 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-34855097

9.

Clinical presentation, management, and biomarkers of neurotoxicity after adoptive immunotherapy with CAR T cells.

Karschnia, Philipp; Jordan, Justin T; Forst, Deborah A; Arrillaga-Romany, Isabel C; Batchelor, Tracy T; Baehring, Joachim M; Clement, Nathan F; Gonzalez Castro, L Nicolas; Herlopian, Aline; Maus, Marcela V; Schwaiblmair, Michaela H; Soumerai, Jacob D; Takvorian, Ronald W; Hochberg, Ephraim P; Barnes, Jeffrey A; Abramson, Jeremy S; Frigault, Matthew J; Dietrich, Jorg.

Blood ; 133(20): 2212-2221, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-30808634

10.

Seizures in patients with cancer.

Gonzalez Castro, L Nicolas; Milligan, Tracey A.

Cancer ; 126(7): 1379-1389, 2020 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-31967671

11.

Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma.

Spitzer, Avishay; Gritsch, Simon; Nomura, Masashi; Jucht, Alexander; Fortin, Jerome; Raviram, Ramya; Weisman, Hannah R; Gonzalez Castro, L Nicolas; Druck, Nicholas; Chanoch-Myers, Rony; Lee, John J Y; Mylvaganam, Ravindra; Lee Servis, Rachel; Fung, Jeremy Man; Lee, Christine K; Nagashima, Hiroaki; Miller, Julie J; Arrillaga-Romany, Isabel; Louis, David N; Wakimoto, Hiroaki; Pisano, Will; Wen, Patrick Y; Mak, Tak W; Sanson, Marc; Touat, Mehdi; Landau, Dan A; Ligon, Keith L; Cahill, Daniel P; Suvà, Mario L; Tirosh, Itay.

Cancer Cell ; 42(5): 904-914.e9, 2024 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-38579724

12.

The Current Landscape of Immune Checkpoint Inhibitor Immunotherapy for Primary and Metastatic Brain Tumors.

Alimonti, Paolo; Gonzalez Castro, L Nicolas.

Antibodies (Basel) ; 12(2)2023 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-37092448

13.

Artificial intelligence in neuro-oncology.

Nakhate, Vihang; Gonzalez Castro, L Nicolas.

Front Neurosci ; 17: 1217629, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-38161802

14.

Diagnosis and Treatment of Paraneoplastic Neurologic Syndromes.

Chiu, Daniel; Rhee, John; Gonzalez Castro, L Nicolas.

Antibodies (Basel) ; 12(3)2023 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-37606434

15.

Characterizing the biology of primary brain tumors and their microenvironment via single-cell profiling methods.

Gonzalez Castro, L Nicolas; Liu, Ilon; Filbin, Mariella.

Neuro Oncol ; 25(2): 234-247, 2023 02 14.

Artigo em Inglês | MEDLINE | ID: mdl-36197833

16.

Evaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma.

Youssef, Gilbert; Rahman, Rifaquat; Bay, Camden; Wang, Wei; Lim-Fat, Mary Jane; Arnaout, Omar; Bi, Wenya Linda; Cagney, Daniel N; Chang, Yuh-Shin; Cloughesy, Timothy F; DeSalvo, Matthew; Ellingson, Benjamin M; Flood, Thomas F; Gerstner, Elizabeth R; Gonzalez Castro, L Nicolas; Guenette, Jeffrey P; Kim, Albert E; Lee, Eudocia Q; McFaline-Figueroa, Jose R; Potter, Christopher A; Reardon, David A; Huang, Raymond Y; Wen, Patrick Y.

J Clin Oncol ; 41(17): 3160-3171, 2023 06 10.

Artigo em Inglês | MEDLINE | ID: mdl-37027809

17.

Isocitrate dehydrogenase (IDH) mutant gliomas: A Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions.

Miller, Julie J; Gonzalez Castro, L Nicolas; McBrayer, Samuel; Weller, Michael; Cloughesy, Timothy; Portnow, Jana; Andronesi, Ovidiu; Barnholtz-Sloan, Jill S; Baumert, Brigitta G; Berger, Mitchell S; Bi, Wenya Linda; Bindra, Ranjit; Cahill, Daniel P; Chang, Susan M; Costello, Joseph F; Horbinski, Craig; Huang, Raymond Y; Jenkins, Robert B; Ligon, Keith L; Mellinghoff, Ingo K; Nabors, L Burt; Platten, Michael; Reardon, David A; Shi, Diana D; Schiff, David; Wick, Wolfgang; Yan, Hai; von Deimling, Andreas; van den Bent, Martin; Kaelin, William G; Wen, Patrick Y.

Neuro Oncol ; 25(1): 4-25, 2023 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-36239925

18.

Glioblastoma in Patients With Multiple Sclerosis.

Berkman, Jillian M; Nakhate, Vihang; Gonzalez Castro, L Nicolas.

Neurohospitalist ; 12(4): 607-616, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-36147751

19.

Clinical Problem Solving: A 56-Year-Old Woman With Right Facial Weakness, Numbness, and Diplopia.

Song, Kun-Wei; Budhu, Joshua; Isroff, Catherine; Siegmund, Stephanie; Gonzalez Castro, L Nicolas.

Neurohospitalist ; 12(3): 512-515, 2022 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-35755233

20.

The cIMPACT-NOW updates and their significance to current neuro-oncology practice.

Gonzalez Castro, L Nicolas; Wesseling, Pieter.

Neurooncol Pract ; 8(1): 4-10, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33664964

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