Detalhe da pesquisa
1.
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Cell
; 149(2): 307-21, 2012 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500798
2.
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals.
J Proteome Res
; 22(10): 3159-3177, 2023 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634194
3.
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
J Biol Chem
; 297(5): 101335, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688654
4.
Enigmatic MELK: The controversy surrounding its complex role in cancer.
J Biol Chem
; 295(24): 8195-8203, 2020 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350113
5.
Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme.
J Biol Chem
; 295(17): 5654-5668, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32156701
6.
Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells.
J Biol Chem
; 295(8): 2359-2374, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896573
7.
Dasatinib Is Preferentially Active in the Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma.
J Proteome Res
; 18(1): 522-534, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30540191
8.
Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology.
J Am Chem Soc
; 141(39): 15700-15709, 2019 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31497954
9.
p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression.
FASEB J
; 32(7): 3892-3902, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29465311
10.
Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals.
Mol Cell Proteomics
; 16(4 suppl 1): S263-S276, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28237943
11.
Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome.
Am J Respir Crit Care Med
; 198(1): 67-76, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29481290
12.
Probing the global kinome and phosphoproteome in Chlamydomonas reinhardtii via sequential enrichment and quantitative proteomics.
Plant J
; 89(2): 416-426, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671103
13.
Measuring Kinase Activity-A Global Challenge.
J Cell Biochem
; 118(11): 3595-3606, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28464261
14.
Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1.
Biochem Biophys Res Commun
; 491(3): 767-772, 2017 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28735864
15.
Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.
Proc Natl Acad Sci U S A
; 111(23): E2414-22, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24872453
16.
An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation.
Mol Cell Proteomics
; 13(5): 1184-97, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24556848
17.
Assessing adaptation of the cancer kinome in response to targeted therapies.
Biochem Soc Trans
; 42(4): 765-9, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109955
18.
The dynamic nature of the kinome.
Biochem J
; 450(1): 1-8, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23343193
19.
Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer.
Science
; 384(6700): eadk0850, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843329
20.
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Science
; 384(6700): eadk0775, 2024 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843331