Pesquisa | BVS Violência e Saúde

1.

The structural basis for HIV-1 Vif antagonism of human APOBEC3G.

Li, Yen-Li; Langley, Caroline A; Azumaya, Caleigh M; Echeverria, Ignacia; Chesarino, Nicholas M; Emerman, Michael; Cheng, Yifan; Gross, John D.

Nature ; 615(7953): 728-733, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36754086

2.

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.

Walter, Marius; Chen, Irene P; Vallejo-Gracia, Albert; Kim, Ik-Jung; Bielska, Olga; Lam, Victor L; Hayashi, Jennifer M; Cruz, Andrew; Shah, Samah; Soveg, Frank W; Gross, John D; Krogan, Nevan J; Jerome, Keith R; Schilling, Birgit; Ott, Melanie; Verdin, Eric.

PLoS Pathog ; 18(9): e1010811, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36095012

3.

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation.

Tibble, Ryan W; Depaix, Anaïs; Kowalska, Joanna; Jemielity, Jacek; Gross, John D.

Nat Chem Biol ; 17(5): 615-623, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33767388

4.

CRL4^AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

Chen, Si-Han; Jang, Gwendolyn M; Hüttenhain, Ruth; Gordon, David E; Du, Dan; Newton, Billy W; Johnson, Jeffrey R; Hiatt, Joseph; Hultquist, Judd F; Johnson, Tasha L; Liu, Yi-Liang; Burton, Lily A; Ye, Jordan; Reichermeier, Kurt M; Stroud, Robert M; Marson, Alexander; Debnath, Jayanta; Gross, John D; Krogan, Nevan J.

EMBO J ; 37(18)2018 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-30166453

5.

Pdc2/Pat1 increases the range of decay factors and RNA bound by the Lsm1-7 complex.

Lobel, Joseph H; Gross, John D.

RNA ; 26(10): 1380-1388, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32513655

6.

Pat1 activates late steps in mRNA decay by multiple mechanisms.

Lobel, Joseph H; Tibble, Ryan W; Gross, John D.

Proc Natl Acad Sci U S A ; 116(47): 23512-23517, 2019 11 19.

Artigo em Inglês | MEDLINE | ID: mdl-31690658

7.

Judge, jury, and executioner: DXO functions as a decapping enzyme and exoribonuclease in pre-mRNA quality control.

Mugridge, Jeffrey S; Gross, John D.

Mol Cell ; 50(1): 2-4, 2013 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-23582258

8.

From systems to structure: bridging networks and mechanism.

Fraser, James S; Gross, John D; Krogan, Nevan J.

Mol Cell ; 49(2): 222-31, 2013 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-23352243

9.

CBFß stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

Kim, Dong Young; Kwon, Eunju; Hartley, Paul D; Crosby, David C; Mann, Sumanjit; Krogan, Nevan J; Gross, John D.

Mol Cell ; 49(4): 632-44, 2013 Feb 21.

Artigo em Inglês | MEDLINE | ID: mdl-23333304

10.

Application of a Schizosaccharomyces pombe Edc1-fused Dcp1-Dcp2 decapping enzyme for transcription start site mapping.

Paquette, David R; Mugridge, Jeffrey S; Weinberg, David E; Gross, John D.

RNA ; 24(2): 251-257, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-29101277

11.

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.

Binning, Jennifer M; Smith, Amber M; Hultquist, Judd F; Craik, Charles S; Caretta Cartozo, Nathalie; Campbell, Melody G; Burton, Lily; La Greca, Florencia; McGregor, Michael J; Ta, Hai M; Bartholomeeusen, Koen; Peterlin, B Matija; Krogan, Nevan J; Sevillano, Natalia; Cheng, Yifan; Gross, John D.

PLoS Pathog ; 14(1): e1006830, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29304101

12.

Control of mRNA decapping by autoinhibition.

Paquette, David R; Tibble, Ryan W; Daifuku, Tristan S; Gross, John D.

Nucleic Acids Res ; 46(12): 6318-6329, 2018 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-29618050

13.

Conformational Dynamics of the HIV-Vif Protein Complex.

Ball, K Aurelia; Chan, Lieza M; Stanley, David J; Tierney, Elise; Thapa, Sampriti; Ta, Hai M; Burton, Lily; Binning, Jennifer M; Jacobson, Matthew P; Gross, John D.

Biophys J ; 116(8): 1432-1445, 2019 04 23.

Artigo em Inglês | MEDLINE | ID: mdl-30961890

14.

Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.

Ziemniak, Marcin; Mugridge, Jeffrey S; Kowalska, Joanna; Rhoads, Robert E; Gross, John D; Jemielity, Jacek.

RNA ; 22(4): 518-29, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26826132

15.

Molecular biology: Messenger RNAs marked for longer life.

Weinberg, David E; Gross, John D.

Nature ; 541(7637): 293-294, 2017 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-28002405

16.

Decapping enzymes STOP "cancer" ribosomes in their tracks.

Mugridge, Jeffrey S; Gross, John D.

EMBO J ; 37(23)2018 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-30455174

17.

Vif hijacks CBF-ß to degrade APOBEC3G and promote HIV-1 infection.

Jäger, Stefanie; Kim, Dong Young; Hultquist, Judd F; Shindo, Keisuke; LaRue, Rebecca S; Kwon, Eunju; Li, Ming; Anderson, Brett D; Yen, Linda; Stanley, David; Mahon, Cathal; Kane, Joshua; Franks-Skiba, Kathy; Cimermancic, Peter; Burlingame, Alma; Sali, Andrej; Craik, Charles S; Harris, Reuben S; Gross, John D; Krogan, Nevan J.

Nature ; 481(7381): 371-5, 2011 Dec 21.

Artigo em Inglês | MEDLINE | ID: mdl-22190037

18.

CBFß and HIV Infection.

Kim, Dong Young; Gross, John D.

Adv Exp Med Biol ; 962: 415-431, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28299671

19.

Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.

Jayaraman, Bhargavi; Mavor, David; Gross, John D; Frankel, Alan D.

Biochemistry ; 54(42): 6545-54, 2015 Oct 27.

Artigo em Inglês | MEDLINE | ID: mdl-26422686

20.

Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.

Floor, Stephen N; Borja, Mark S; Gross, John D.

Proc Natl Acad Sci U S A ; 109(8): 2872-7, 2012 Feb 21.

Artigo em Inglês | MEDLINE | ID: mdl-22323607

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