Pesquisa | BVS Violência e Saúde

1.

RNA promotes the formation of spatial compartments in the nucleus.

Quinodoz, Sofia A; Jachowicz, Joanna W; Bhat, Prashant; Ollikainen, Noah; Banerjee, Abhik K; Goronzy, Isabel N; Blanco, Mario R; Chovanec, Peter; Chow, Amy; Markaki, Yolanda; Thai, Jasmine; Plath, Kathrin; Guttman, Mitchell.

Cell ; 184(23): 5775-5790.e30, 2021 11 11.

Artigo em Inglês | MEDLINE | ID: mdl-34739832

2.

Xist nucleates local protein gradients to propagate silencing across the X chromosome.

Markaki, Yolanda; Gan Chong, Johnny; Wang, Yuying; Jacobson, Elsie C; Luong, Christy; Tan, Shawn Y X; Jachowicz, Joanna W; Strehle, Mackenzie; Maestrini, Davide; Banerjee, Abhik K; Mistry, Bhaven A; Dror, Iris; Dossin, Francois; Schöneberg, Johannes; Heard, Edith; Guttman, Mitchell; Chou, Tom; Plath, Kathrin.

Cell ; 184(25): 6174-6192.e32, 2021 12 09.

Artigo em Inglês | MEDLINE | ID: mdl-34813726

3.

Long non-coding RNAs: definitions, functions, challenges and recommendations.

Mattick, John S; Amaral, Paulo P; Carninci, Piero; Carpenter, Susan; Chang, Howard Y; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E; Fitzgerald, Katherine A; Gingeras, Thomas R; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B; Lee, Jeannie T; Mendell, Joshua T; Mercer, Timothy R; Moore, Kathryn J; Nakagawa, Shinichi; Rinn, John L; Spector, David L; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E; Wu, Mian.

Nat Rev Mol Cell Biol ; 24(6): 430-447, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36596869

4.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.

Banerjee, Abhik K; Blanco, Mario R; Bruce, Emily A; Honson, Drew D; Chen, Linlin M; Chow, Amy; Bhat, Prashant; Ollikainen, Noah; Quinodoz, Sofia A; Loney, Colin; Thai, Jasmine; Miller, Zachary D; Lin, Aaron E; Schmidt, Madaline M; Stewart, Douglas G; Goldfarb, Daniel; De Lorenzo, Giuditta; Rihn, Suzannah J; Voorhees, Rebecca M; Botten, Jason W; Majumdar, Devdoot; Guttman, Mitchell.

Cell ; 183(5): 1325-1339.e21, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33080218

5.

Nuclear compartmentalization as a mechanism of quantitative control of gene expression.

Bhat, Prashant; Honson, Drew; Guttman, Mitchell.

Nat Rev Mol Cell Biol ; 22(10): 653-670, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34341548

6.

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus.

Quinodoz, Sofia A; Ollikainen, Noah; Tabak, Barbara; Palla, Ali; Schmidt, Jan Marten; Detmar, Elizabeth; Lai, Mason M; Shishkin, Alexander A; Bhat, Prashant; Takei, Yodai; Trinh, Vickie; Aznauryan, Erik; Russell, Pamela; Cheng, Christine; Jovanovic, Marko; Chow, Amy; Cai, Long; McDonel, Patrick; Garber, Manuel; Guttman, Mitchell.

Cell ; 174(3): 744-757.e24, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-29887377

7.

Linking Protein and RNA Function within the Same Gene.

Szempruch, Anthony; Guttman, Mitchell.

Cell ; 168(5): 753-755, 2017 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-28235192

8.

Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo.

Guo, Jimmy K; Blanco, Mario R; Walkup, Ward G; Bonesteele, Grant; Urbinati, Carl R; Banerjee, Abhik K; Chow, Amy; Ettlin, Olivia; Strehle, Mackenzie; Peyda, Parham; Amaya, Enrique; Trinh, Vickie; Guttman, Mitchell.

Mol Cell ; 84(7): 1271-1289.e12, 2024 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-38387462

9.

A Guide to Packing Your DNA.

Dekker, Job; Guttman, Mitchell; Lomvardas, Stavros.

Cell ; 165(2): 259-61, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-27058655

10.

Xist nucleates local protein gradients to propagate silencing across the X chromosome.

Markaki, Yolanda; Chong, Johnny Gan; Wang, Yuying; Jacobson, Elsie C; Luong, Christy; Tan, Shawn Y X; Jachowicz, Joanna W; Strehle, Mackenzie; Maestrini, Davide; Banerjee, Abhik K; Mistry, Bhaven A; Dror, Iris; Dossin, Francois; SchÓ§neberg, Johannes; Heard, Edith; Guttman, Mitchell; Chou, Tom; Plath, Kathrin.

Cell ; 184(25): 6212, 2021 Dec 09.

Artigo em Inglês | MEDLINE | ID: mdl-34890555

11.

Genome organization around nuclear speckles drives mRNA splicing efficiency.

Bhat, Prashant; Chow, Amy; Emert, Benjamin; Ettlin, Olivia; Quinodoz, Sofia A; Strehle, Mackenzie; Takei, Yodai; Burr, Alex; Goronzy, Isabel N; Chen, Allen W; Huang, Wesley; Ferrer, Jose Lorenzo M; Soehalim, Elizabeth; Goh, Say-Tar; Chari, Tara; Sullivan, Delaney K; Blanco, Mario R; Guttman, Mitchell.

Nature ; 629(8014): 1165-1173, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38720076

12.

RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.

Engreitz, Jesse M; Sirokman, Klara; McDonel, Patrick; Shishkin, Alexander A; Surka, Christine; Russell, Pamela; Grossman, Sharon R; Chow, Amy Y; Guttman, Mitchell; Lander, Eric S.

Cell ; 159(1): 188-199, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25259926

13.

Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.

Schwartz, Schraga; Bernstein, Douglas A; Mumbach, Maxwell R; Jovanovic, Marko; Herbst, Rebecca H; León-Ricardo, Brian X; Engreitz, Jesse M; Guttman, Mitchell; Satija, Rahul; Lander, Eric S; Fink, Gerald; Regev, Aviv.

Cell ; 159(1): 148-162, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25219674

14.

Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.

Engreitz, Jesse M; Ollikainen, Noah; Guttman, Mitchell.

Nat Rev Mol Cell Biol ; 17(12): 756-770, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27780979

15.

Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins.

Guttman, Mitchell; Russell, Pamela; Ingolia, Nicholas T; Weissman, Jonathan S; Lander, Eric S.

Cell ; 154(1): 240-51, 2013 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-23810193

16.

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.

Gifford, Casey A; Ziller, Michael J; Gu, Hongcang; Trapnell, Cole; Donaghey, Julie; Tsankov, Alexander; Shalek, Alex K; Kelley, David R; Shishkin, Alexander A; Issner, Robbyn; Zhang, Xiaolan; Coyne, Michael; Fostel, Jennifer L; Holmes, Laurie; Meldrim, Jim; Guttman, Mitchell; Epstein, Charles; Park, Hongkun; Kohlbacher, Oliver; Rinn, John; Gnirke, Andreas; Lander, Eric S; Bernstein, Bradley E; Meissner, Alexander.

Cell ; 153(5): 1149-63, 2013 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-23664763

17.

High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection.

Vangala, Pranitha; Murphy, Rachel; Quinodoz, Sofia A; Gellatly, Kyle; McDonel, Patrick; Guttman, Mitchell; Garber, Manuel.

Mol Cell ; 80(2): 359-373.e8, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-32991830

18.

Integrated spatial genomics reveals global architecture of single nuclei.

Takei, Yodai; Yun, Jina; Zheng, Shiwei; Ollikainen, Noah; Pierson, Nico; White, Jonathan; Shah, Sheel; Thomassie, Julian; Suo, Shengbao; Eng, Chee-Huat Linus; Guttman, Mitchell; Yuan, Guo-Cheng; Cai, Long.

Nature ; 590(7845): 344-350, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33505024

19.

Publisher Correction: A protein assembly mediates Xist localization and gene silencing.

Pandya-Jones, Amy; Markaki, Yolanda; Serizay, Jacques; Chitiashvili, Tsotne; Leon, Walter R Mancia; Damianov, Andrey; Chronis, Constantinos; Papp, Bernadett; Chen, Chun-Kan; McKee, Robin; Wang, Xiao-Jun; Chau, Anthony; Sabri, Shan; Leonhardt, Heinrich; Zheng, Sika; Guttman, Mitchell; Black, Douglas L; Plath, Kathrin.

Nature ; 586(7830): E30, 2020 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-33005055

20.

A protein assembly mediates Xist localization and gene silencing.

Pandya-Jones, Amy; Markaki, Yolanda; Serizay, Jacques; Chitiashvili, Tsotne; Mancia Leon, Walter R; Damianov, Andrey; Chronis, Constantinos; Papp, Bernadett; Chen, Chun-Kan; McKee, Robin; Wang, Xiao-Jun; Chau, Anthony; Sabri, Shan; Leonhardt, Heinrich; Zheng, Sika; Guttman, Mitchell; Black, Douglas L; Plath, Kathrin.

Nature ; 587(7832): 145-151, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32908311

BVS Violência e Saúde

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar:

RNA promotes the formation of spatial compartments in the nucleus.

Xist nucleates local protein gradients to propagate silencing across the X chromosome.

Long non-coding RNAs: definitions, functions, challenges and recommendations.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.

Nuclear compartmentalization as a mechanism of quantitative control of gene expression.

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus.

Linking Protein and RNA Function within the Same Gene.

Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo.

A Guide to Packing Your DNA.

Xist nucleates local protein gradients to propagate silencing across the X chromosome.

Genome organization around nuclear speckles drives mRNA splicing efficiency.

RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.

Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.

Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.

Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins.

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.

High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection.

Integrated spatial genomics reveals global architecture of single nuclei.

Publisher Correction: A protein assembly mediates Xist localization and gene silencing.

A protein assembly mediates Xist localization and gene silencing.